4-carboxy-3-hydroxyphenylglycine has been researched along with Seizures in 3 studies
4-carboxy-3-hydroxyphenylglycine: weak agonist at metabotropic glutamate receptors; occludes the action of 1-aminocyclopentyl-1,3-dicarboxylate in hippocampus
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Generalised clonic--tonic seizures were completely suppressed and the metabolic changes were markedly ameliorated, there being only a 1." | 5.31 | Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists. ( Folbergrová, J; Haugvicová, R; Mares, P, 2001) |
| "Generalised clonic--tonic seizures were completely suppressed and the metabolic changes were markedly ameliorated, there being only a 1." | 1.31 | Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists. ( Folbergrová, J; Haugvicová, R; Mares, P, 2001) |
| "A modest increase in electrical seizure threshold was observed in mice injected with (S)-4C3HPG." | 1.29 | Modulation of seizure activity in mice by metabotropic glutamate receptor ligands. ( Dalby, NO; Thomsen, C, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomsen, C | 2 |
| Klitgaard, H | 1 |
| Sheardown, M | 1 |
| Jackson, HC | 1 |
| Eskesen, K | 1 |
| Jacobsen, P | 1 |
| Treppendahl, S | 1 |
| Suzdak, PD | 1 |
| Dalby, NO | 1 |
| Folbergrová, J | 1 |
| Haugvicová, R | 1 |
| Mares, P | 1 |
3 other studies available for 4-carboxy-3-hydroxyphenylglycine and Seizures
| Article | Year |
|---|---|
(S)-4-carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Cricetinae; Dose-Response Relationship, Drug; Glycin | 1994 |
Modulation of seizure activity in mice by metabotropic glutamate receptor ligands.
Topics: Animals; Anticonvulsants; Benzoates; Glycine; Male; Mice; Mice, Inbred DBA; Receptors, Metabotropic | 1996 |
Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Cyclobutanes; Cyclopropanes; Dose-Response Relati | 2001 |