pyrazinamide has been researched along with Seizures in 5 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levofloxacin is an effective bactericidal category III antitubercular drug." | 2.82 | Safety and efficacy of additional levofloxacin in tuberculous meningitis: A randomized controlled pilot study. ( Betai, S; Bhoi, SK; Kalita, J; Misra, UK, 2016) |
| "Antituberculous drugs are generally safe but can occasionally be associated with life-threatening complications." | 1.32 | Antituberculous therapy-induced toxicity. ( Abraham, OC; Bharat, A; Mathai, D; Subhash, HS; Vedkumar, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalita, J | 2 |
| Misra, UK | 2 |
| Singh, VK | 1 |
| Pandey, PC | 1 |
| Thomas, J | 1 |
| Bhoi, SK | 1 |
| Betai, S | 1 |
| Bharat, A | 1 |
| Vedkumar, M | 1 |
| Subhash, HS | 1 |
| Abraham, OC | 1 |
| Mathai, D | 1 |
| Jimonet, P | 1 |
| Bohme, GA | 1 |
| Bouquerel, J | 1 |
| Boireau, A | 1 |
| Damour, D | 1 |
| Debono, MW | 1 |
| Genevois-Borella, A | 1 |
| Hardy, JC | 1 |
| Hubert, P | 1 |
| Manfré, F | 1 |
| Nemecek, P | 1 |
| Pratt, J | 1 |
| Randle, JC | 1 |
| Ribeill, Y | 1 |
| Stutzmann, JM | 1 |
| Vuilhorgne, M | 1 |
| Mignani, S | 1 |
| Herlevsen, P | 1 |
| Nielsen, C | 1 |
| Pedersen, JT | 1 |
1 trial available for pyrazinamide and Seizures
| Article | Year |
|---|---|
Safety and efficacy of additional levofloxacin in tuberculous meningitis: A randomized controlled pilot study.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Disability Evaluation; Drug Therapy, Combination; Et | 2016 |
4 other studies available for pyrazinamide and Seizures
| Article | Year |
|---|---|
Inclusion of Mechanical Ventilation in Severity Staging of Tuberculous Meningitis Improves Outcome Prediction.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Antitubercular Agents; Child; Child, Preschool; Consciousn | 2020 |
Antituberculous therapy-induced toxicity.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Fever; Humans; Isoniazid; Male; Pyrazinamid | 2003 |
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Combinatorial Ch | 2001 |
Convulsions after treatment with pyrazinamide.
Topics: Humans; Infant; Male; Pyrazinamide; Seizures; Tuberculosis, Pulmonary | 1987 |