clioquinol has been researched along with Seizures in 5 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Several studies have shown that epileptic seizures increase hippocampal neurogenesis in the adult." | 1.38 | Zinc chelation reduces hippocampal neurogenesis after pilocarpine-induced seizure. ( Choi, BY; Jang, BG; Kim, JH; Kwon, LM; Sohn, M; Song, HK; Suh, SW, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lukovits, I | 1 |
| Lopata, A | 1 |
| Kim, JH | 1 |
| Jang, BG | 1 |
| Choi, BY | 1 |
| Kwon, LM | 1 |
| Sohn, M | 1 |
| Song, HK | 1 |
| Suh, SW | 1 |
| Buchanan, DS | 1 |
| Tateishi, J | 1 |
| Kuroda, S | 1 |
| Saito, A | 1 |
| Otsuki, S | 1 |
| Zeiller, P | 1 |
| Sensch, KH | 1 |
| Dahme, E | 1 |
5 other studies available for clioquinol and Seizures
| Article | Year |
|---|---|
Decomposition of pharmacological activity indices into mutually independent components using principal component analysis.
Topics: Animals; Anti-Infective Agents; Benzodiazepines; Hydroxyquinolines; Mathematics; Pharmacology; Rifam | 1980 |
Zinc chelation reduces hippocampal neurogenesis after pilocarpine-induced seizure.
Topics: Animals; Cell Death; Cell Proliferation; Chelating Agents; Clioquinol; Dentate Gyrus; Doublecortin P | 2012 |
Iatrogenic causes of neurologic disorders: part 1. Affect, convulsions, and encephalopathies.
Topics: Affective Symptoms; Aged; Antiparkinson Agents; Brain Diseases; Clioquinol; Cognition Disorders; Hum | 1978 |
Strain differences in dogs for neurotoxicity of clioquinol.
Topics: Animals; Clioquinol; Dogs; Hybridization, Genetic; Nervous System; Seizures | 1972 |
[Various effects of halogenated oxyquinolines inducing neurotoxic symptoms in the animal organism].
Topics: Administration, Oral; Amebicides; Animals; Cats; Chloroquinolinols; Clioquinol; Epilepsy; Female; Hi | 1972 |