Page last updated: 2024-11-06

corticosterone and Seizures

corticosterone has been researched along with Seizures in 74 studies

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
" Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h."8.31Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023)
" In this study, using rat TBI model (lateral fluid percussion cortical injury), we assessed potential association of immediate posttraumatic seizures and changes in corticosterone (CS) levels with neuroinflammation and neuronal cell loss in the hippocampus."8.02Neuroinflammation and Neuronal Loss in the Hippocampus Are Associated with Immediate Posttraumatic Seizures and Corticosterone Elevation in Rats. ( Frankevich, SO; Gulyaeva, NV; Komoltsev, IG; Moiseeva, JV; Novikova, MR; Onufriev, MV; Shirobokova, NI; Volkova, AA, 2021)
" We investigated the mechanistic roles of endocrine activity and γ-aminobutyric acid type A receptor (GABAAR)-mediated excitation in electroencephalographic seizures caused by the GABAAR-selective anesthetic propofol in neonatal rats."7.81Propofol-induced electroencephalographic seizures in neonatal rats: the role of corticosteroids and γ-aminobutyric acid type A receptor-mediated excitation. ( Gravenstein, N; Martynyuk, A; Perez-Downes, J; Seubert, C; Tan, S; Willis, J; Xu, C; Zhu, W, 2015)
"The purpose of this investigation was to determine the effects of adrenalectomy and adrenalectomy with corticosterone replacement on pain sensitivity and on the pharmacodynamics of a central nervous system depressant, phenobarbital, and a central nervous system stimulant, theophylline."7.68Kinetics of drug action in disease states. XLI. Effect of adrenalectomy on the hypnotic activity of phenobarbital, the neurotoxicity of theophylline and pain sensitivity in rats. ( Hoffman, A; Levy, G, 1993)
"The reactivity of hypophyseal-adrenocortical system, the receptor binding of 3H-corticosterone, and the catecholamines content in cerebral monoaminergic structures were studied in the Krushinskiĭ-Molodkina rats predisposed to audiogenic seizures and in control Wistar rats."7.68[The receptor binding of 3H-corticosterone and the dopamine content in the striatum of rats with a predisposition to audiogenic seizures]. ( Garina, IA; Lopatina, NG; Pivina, SG; Rakitskaia, VV; Shaliapina, VG, 1990)
"Ferulic acid treatment, on the other hand, significantly decreased seizure susceptibility and depression like behavior, possibly because of increased progesterone, restored estradiol, corticosterone, monoamines, and GAD enzyme activity."5.72Ferulic acid inhibits catamenial epilepsy through modulation of female hormones. ( Dhillon, HK; Goel, RK; Singh, T, 2022)
"Baicalein was injected intraperitoneally to TLE rats for two weeks after the onset of spontaneous recurrent seizures (SRS)."5.51Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats. ( Ding, JQ; Li, W; Qian, X; Wang, ZR; Zhang, M; Zhang, TY; Zheng, JJ; Zhong, JG, 2019)
"Electroconvulsive seizure (ECS)-treatment, an animal model for the antidepressant treatment electroconvulsive therapy, can enhance proliferation of glial cells."5.33Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures. ( Ekstrand, J; Hellsten, J; Lindgren, H; Tingström, A; Wennström, M, 2006)
"the glucose paradox of cerebral ischemia, is a well-established phenomenon that has prompted clinicians around the world to closely monitor and control blood glucose levels in surgical cases at high risk for ischemic episodes."5.32The glucose paradox of cerebral ischemia: evidence for corticosterone involvement. ( Payne, RS; Schurr, A; Tseng, MT, 2003)
" Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h."4.31Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023)
" In this study, using rat TBI model (lateral fluid percussion cortical injury), we assessed potential association of immediate posttraumatic seizures and changes in corticosterone (CS) levels with neuroinflammation and neuronal cell loss in the hippocampus."4.02Neuroinflammation and Neuronal Loss in the Hippocampus Are Associated with Immediate Posttraumatic Seizures and Corticosterone Elevation in Rats. ( Frankevich, SO; Gulyaeva, NV; Komoltsev, IG; Moiseeva, JV; Novikova, MR; Onufriev, MV; Shirobokova, NI; Volkova, AA, 2021)
" We investigated the mechanistic roles of endocrine activity and γ-aminobutyric acid type A receptor (GABAAR)-mediated excitation in electroencephalographic seizures caused by the GABAAR-selective anesthetic propofol in neonatal rats."3.81Propofol-induced electroencephalographic seizures in neonatal rats: the role of corticosteroids and γ-aminobutyric acid type A receptor-mediated excitation. ( Gravenstein, N; Martynyuk, A; Perez-Downes, J; Seubert, C; Tan, S; Willis, J; Xu, C; Zhu, W, 2015)
" Here, we tested the hypothesis that increased levels of the stress-associated hormone corticosterone (CORT) would increase epileptiform activity and spontaneous seizure frequency in mice rendered epileptic following pilocarpine-induced status epilepticus."3.78Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy. ( Batie, M; Castro, OW; Danzer, SC; Garcia-Cairasco, N; Gardner, M; Herman, JP; Holland, KD; McKlveen, JM; Pun, RY; Santos, VR, 2012)
" Here, tonic-clonic seizures were induced with a convulsive dose of pentylenetetrazole (PTZ), and acute seizure recurrence was evoked with a subconvulsive dose of the drug."3.76Stress within the postseizure time window inhibits seizure recurrence. ( Cao, J; Duan, TT; Mao, RR; Tan, JW; Tian, M; Xu, L; Zhou, QX, 2010)
" Housing conditions did not alter the anticonvulsant activity of diazepam or ethanol, although the anticonvulsant effect of ethanol was significantly greater against PTZ-induced seizures."3.72Sex differences in effects of mild chronic stress on seizure risk and GABAA receptors in rats. ( Chadda, R; Devaud, LL, 2004)
" The main goal of this study was to examine the effects of down-regulation of the HPA-axis on the hypoxia/ischaemia-induced (1) rise of plasma corticosterone levels, (2) seizures, and (3) brain damage."3.69Down-regulation of the hypothalamo-pituitary-adrenal axis reduces brain damage and number of seizures following hypoxia/ischaemia in rats. ( Kemper, RH; Knollema, S; Korf, J; Krugers, HJ; Ter Horst, GJ, 1995)
"The reactivity of hypophyseal-adrenocortical system, the receptor binding of 3H-corticosterone, and the catecholamines content in cerebral monoaminergic structures were studied in the Krushinskiĭ-Molodkina rats predisposed to audiogenic seizures and in control Wistar rats."3.68[The receptor binding of 3H-corticosterone and the dopamine content in the striatum of rats with a predisposition to audiogenic seizures]. ( Garina, IA; Lopatina, NG; Pivina, SG; Rakitskaia, VV; Shaliapina, VG, 1990)
" EtOH withdrawal seizures of WSP mice were significantly increased by chronic and acute corticosterone treatment, whereas those of the WSR mice were unaffected."3.68Differential modulation by the stress axis of ethanol withdrawal seizure expression in WSP and WSR mice. ( Chu, HP; Crabbe, JC; Keith, LD; Roberts, AJ, 1991)
" Northern blot hybridization analysis revealed 4 discrete BDNF mRNA species in L929 cells and rat hippocampus after induction of seizures with kainic acid."3.68Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts. ( D'Mello, SR; Heinrich, G; Jiang, C; Lamberti, C; Martin, SC, 1992)
"The purpose of this investigation was to determine the effects of adrenalectomy and adrenalectomy with corticosterone replacement on pain sensitivity and on the pharmacodynamics of a central nervous system depressant, phenobarbital, and a central nervous system stimulant, theophylline."3.68Kinetics of drug action in disease states. XLI. Effect of adrenalectomy on the hypnotic activity of phenobarbital, the neurotoxicity of theophylline and pain sensitivity in rats. ( Hoffman, A; Levy, G, 1993)
"We report that glucocorticoids significantly facilitated the development of cocaine-induced kindled seizures."3.68Facilitation of cocaine kindling by glucocorticoids in rats. ( DeBellis, MD; Demas, J; Glowa, JR; Gold, PW; Kling, MA; Pluznik, D; Schulkin, J; Smith, MA, 1993)
"The influence of adrenocorticosteroids on seizures and wet dog shakes (WDS) induced by deep prepyriform cortex kindling was studied by bilateral adrenalectomy and corticosterone replacement."3.67Effects of corticosterone on shaking and seizure behavior induced by deep prepyriform cortex kindling. ( Hong, JS; Lee, PH; Mitchell, CL; Zhao, DY, 1987)
"Ferulic acid treatment, on the other hand, significantly decreased seizure susceptibility and depression like behavior, possibly because of increased progesterone, restored estradiol, corticosterone, monoamines, and GAD enzyme activity."1.72Ferulic acid inhibits catamenial epilepsy through modulation of female hormones. ( Dhillon, HK; Goel, RK; Singh, T, 2022)
"Febrile seizures (FS) are common, affecting 2-5% of children between the ages of 3 months and 6 years."1.62Sex differences in the developing brain impact stress-induced epileptogenicity following hyperthermia-induced seizures. ( Awad, PN; Bilodeau, GA; Bosoi, CM; Chen, JS; Desgent, S; Duss, S; Elkaim, LM; Lewis, EC; Salam, MT; Sanon, NT; Sawan, M; Simard, A; Weil, AG; Wolf, DC, 2021)
"Epileptic seizures are the most common neurological diseases that change the function of neurovascular unit at molecular levels accompanied by activation of a wide variety of neurodegenerative cascades."1.62Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice. ( Darabi, S; Faghihi, N; Mohammadi, MT; Sarahian, N, 2021)
"The latency(s) to anoxic convulsion was recorded on day 7."1.56Methyl jasmonate delays the latency to anoxic convulsions by normalizing the brain levels of oxidative stress biomarkers and serum corticosterone contents in mice with repeated anoxic stress. ( Adelaja, AO; Aluko, OM; Oluwole, OG; Umukoro, S, 2020)
"Baicalein was injected intraperitoneally to TLE rats for two weeks after the onset of spontaneous recurrent seizures (SRS)."1.51Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats. ( Ding, JQ; Li, W; Qian, X; Wang, ZR; Zhang, M; Zhang, TY; Zheng, JJ; Zhong, JG, 2019)
"From P7 to P10, the threshold to seizures induced by flurothyl was used as an index of seizure susceptibility."1.43Enhanced susceptibility to seizures modulated by high interleukin-1β levels during early life malnutrition. ( Habekost Oliveira, V; Lahorgue Nunes, M; Simão, F, 2016)
" Most importantly, Pum2-deficient mice showed spontaneous EEG abnormalities and had lower seizure thresholds using a convulsing dosage of pentylenetetrazole."1.37Pumilio-2 function in the mouse nervous system. ( Brüstle, O; Colas, D; Heller, HC; Pera, RA; Siemen, H, 2011)
"We measured seizure-induced serum CORT levels and post-kindling neurogenesis (using BrdU)."1.37Early life stress enhancement of limbic epileptogenesis in adult rats: mechanistic insights. ( Jones, NC; Kumar, G; Morris, MJ; O'Brien, TJ; Rees, S; Salzberg, MR, 2011)
"Pilocarpine was administered on postnatal day 25 and mortality rates were measured after 2 and 24h."1.37Prenatal exposure to restraint or predator stresses attenuates field excitatory postsynaptic potentials in infant rats. ( Ahmadzadeh, R; Roshan-Milani, S; Saboory, E, 2011)
"In contrast, the seizure prone DBA/2J inbred strain and the Withdrawal Seizure-Prone (WSP) selected line exhibited decreased sensitivity to ALLO's anticonvulsant effect during ethanol withdrawal, with no change in sensitivity in the Withdrawal Seizure-Resistant (WSR) line."1.35Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice. ( Beckley, EH; Crabbe, JC; Finn, DA; Fretwell, AM; Gililland, KR; Tanchuck, MA, 2008)
"Depression is frequently reported in epilepsy patients; however, mechanisms of co-morbidity between epilepsy and depression are poorly understood."1.35Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy. ( Bragin, A; Kwon, YS; Mazarati, AM; Pineda, E; Sankar, R; Shin, D; Taylor, AN; Tio, D, 2009)
"In the present studies, genetically seizure susceptible El and non-susceptible ddY control mice were exposed to tail suspension, foot-shock and social stressors in order to test the hypothesis that neural and physiological responses to such stimuli would be exaggerated in the El strain."1.34Neural, endocrine and electroencephalographic hyperreactivity to human contact: a diathesis-stress model of seizure susceptibility in El mice. ( Forcelli, PA; Heinrichs, SC; Orefice, LL, 2007)
"Handling-induced convulsions (HICs) were scored at baseline, and then over a 24 h period after EtOH or saline injection."1.34Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice. ( Finn, DA; Gorin-Meyer, RE; Long, SL; Tanchuck, MA; Wiren, KM; Yoneyama, N, 2007)
"Electroconvulsive seizure (ECS)-treatment, an animal model for the antidepressant treatment electroconvulsive therapy, can enhance proliferation of glial cells."1.33Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures. ( Ekstrand, J; Hellsten, J; Lindgren, H; Tingström, A; Wennström, M, 2006)
"the glucose paradox of cerebral ischemia, is a well-established phenomenon that has prompted clinicians around the world to closely monitor and control blood glucose levels in surgical cases at high risk for ischemic episodes."1.32The glucose paradox of cerebral ischemia: evidence for corticosterone involvement. ( Payne, RS; Schurr, A; Tseng, MT, 2003)
"Stress affects seizure susceptibility in animals and humans, but the underlying mechanisms are obscure."1.31Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility. ( Reddy, DS; Rogawski, MA, 2002)
"Other childhood seizures are also responsive to ACTH."1.31The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats. ( Burnham, WM; Edwards, HE; Vimal, S, 2002)
" It was reported to potentiate GABA-mediated chloride current in cultured cells with a moderate intrinsic activity and a biphasic dose-response relationship."1.30Anxiolytic-like effects of PNU-101017, a partial agonist at the benzodiazepine receptor. ( Carter, DB; Franklin, SR; Jacobsen, EJ; Needham, LM; Sethy, VH; Tang, AH; Von Voigtlander, PF, 1997)
"One week after seizures, there were no differences in the water maze performance of the remaining animals."1.30Prenatal stress reduces the effectiveness of the neurosteroid 3 alpha,5 alpha-THP to block kainic-acid-induced seizures. ( Bayon, LE; Frye, CA, 1999)
"In experimental-seizure rats, adrenalectomy did not alter the direction or basic pattern of seizure-induced changes in neurotrophin expression but did change the time courses and magnitudes of these effects."1.29Cell-specific modulation of basal and seizure-induced neurotrophin expression by adrenalectomy. ( Berschauer, R; Gall, C; Lauterborn, J, 1995)
"CRH-induced seizure duration (88."1.29ACTH does not control neonatal seizures induced by administration of exogenous corticotropin-releasing hormone. ( Baram, TZ; Schultz, L, 1995)
"Both convulsion susceptibility and plasma corticosteroid levels display circadian rhythmicity."1.29Sensitivity of the circadian rhythm of kainic acid-induced convulsion susceptibility to manipulations of corticosterone levels and mineralocorticoid receptor binding. ( Keith, LD; Roberts, AJ, 1994)
"These results suggest that withdrawal convulsions following acute ethanol, pentobarbital, and diazepam are sensitive to modulation by corticosterone and they support the hypothesis that stress may increase drug withdrawal severity."1.29Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice. ( Crabbe, JC; Keith, LD; Roberts, AJ, 1994)
"Other convulsion types, e."1.29Mineralocorticoid receptors mediate the enhancing effects of corticosterone on convulsion susceptibility in mice. ( Keith, LD; Roberts, AJ, 1994)
"However, the duration of convulsions and the elevation of corticosterone levels after the nicotine injection showed significant decreases in old rats compared with those in young rats."1.28Effects of acute administration of nicotine on convulsive movements and blood levels of corticosterone in old rats. ( Kita, T; Nakashima, T; Okamoto, M; Okuda, H; Tanaka, T, 1992)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199012 (16.22)18.7374
1990's21 (28.38)18.2507
2000's17 (22.97)29.6817
2010's16 (21.62)24.3611
2020's8 (10.81)2.80

Authors

AuthorsStudies
Wolf, DC1
Desgent, S1
Sanon, NT1
Chen, JS1
Elkaim, LM1
Bosoi, CM1
Awad, PN1
Simard, A1
Salam, MT1
Bilodeau, GA1
Duss, S1
Sawan, M1
Lewis, EC1
Weil, AG1
Buchecker, V1
Koska, I1
Pace, C1
Talbot, SR1
Palme, R1
Bleich, A1
Potschka, H1
Dhillon, HK1
Singh, T1
Goel, RK1
Kraus, KL1
Nawreen, N1
Godale, CM1
Chordia, AP1
Packard, B1
LaSarge, CL1
Herman, JP2
Danzer, SC2
Dezsi, G1
Ozturk, E1
Harris, G1
Paul, C1
O'Brien, TJ2
Jones, NC2
Adelaja, AO1
Oluwole, OG1
Aluko, OM1
Umukoro, S1
Sarahian, N1
Mohammadi, MT1
Darabi, S1
Faghihi, N1
Komoltsev, IG1
Frankevich, SO1
Shirobokova, NI1
Volkova, AA1
Onufriev, MV1
Moiseeva, JV1
Novikova, MR1
Gulyaeva, NV1
Hooper, A1
Paracha, R1
Maguire, J2
Umeoka, EHL1
Robinson, EJ1
Turimella, SL1
van Campen, JS1
Motta-Teixeira, LC1
Sarabdjitsingh, RA1
Garcia-Cairasco, N2
Braun, K1
de Graan, PN1
Joëls, M1
Qian, X1
Wang, ZR1
Zheng, JJ1
Ding, JQ1
Zhong, JG1
Zhang, TY1
Li, W1
Zhang, M1
Kyeremanteng, C1
MacKay, JC1
James, JS1
Kent, P2
Cayer, C1
Anisman, H2
Merali, Z2
Kim, CH1
Park, SH1
Sim, YB1
Sharma, N1
Kim, SS1
Lim, SM1
Jung, JS1
Suh, HW1
Willis, J1
Zhu, W1
Perez-Downes, J1
Tan, S1
Xu, C1
Seubert, C1
Gravenstein, N1
Martynyuk, A1
MacKenzie, G1
Simão, F1
Habekost Oliveira, V1
Lahorgue Nunes, M1
Hashemi, P1
Roshan-Milani, S3
Saboory, E3
Ebrahimi, L1
Soltanineghad, M1
Mazarati, AM1
Shin, D1
Kwon, YS1
Bragin, A1
Pineda, E1
Tio, D1
Taylor, AN1
Sankar, R1
Perry, MA1
Ryan, CL1
Tasker, RA1
Zhou, QX1
Mao, RR1
Duan, TT1
Tan, JW1
Tian, M1
Cao, J1
Xu, L1
Flores-Gracia, C1
Nuche-Bricaire, A1
Crespo-Ramírez, M1
Miledi, R1
Fuxe, K1
Pérez de la Mora, M1
Ahmadzadeh, R2
Pilehvarian, AA1
Kumar, G1
Morris, MJ1
Rees, S1
Salzberg, MR1
Siemen, H1
Colas, D1
Heller, HC1
Brüstle, O1
Pera, RA1
Castro, OW1
Santos, VR1
Pun, RY1
McKlveen, JM1
Batie, M1
Holland, KD1
Gardner, M1
Payne, RS1
Tseng, MT1
Schurr, A1
Knuth, ED1
Etgen, AM1
Chadda, R2
Devaud, LL3
Wennström, M1
Hellsten, J1
Ekstrand, J1
Lindgren, H1
Tingström, A1
Alele, PE1
Forcelli, PA1
Orefice, LL1
Heinrichs, SC1
Gorin-Meyer, RE1
Wiren, KM1
Tanchuck, MA2
Long, SL1
Yoneyama, N1
Finn, DA3
Gililland, KR2
Beckley, EH1
Fretwell, AM1
Crabbe, JC4
Grahame-Smith, DG1
Nikitina, MM1
Romanova, LG1
Lauterborn, J1
Berschauer, R1
Gall, C1
Krugers, HJ1
Knollema, S1
Kemper, RH1
Ter Horst, GJ1
Korf, J1
Baram, TZ1
Schultz, L1
Roberts, AJ5
Keith, LD5
Andreatini, R1
Leite, JR1
Okamoto, M2
Kita, T2
Okuda, H2
Tanaka, T2
Nakashima, T2
Kling, MA1
Smith, MA1
Glowa, JR1
Pluznik, D1
Demas, J1
DeBellis, MD1
Gold, PW1
Schulkin, J1
Abel, EL1
Berman, RF1
Hoffman, A1
Levy, G1
Sun, FY1
Costa, E1
Mocchetti, I1
Tang, AH1
Franklin, SR1
Carter, DB1
Sethy, VH1
Needham, LM1
Jacobsen, EJ1
Von Voigtlander, PF1
Frye, CA1
Bayon, LE1
Michaud, D1
McIntyre, D1
Haimovici, A1
Wang, Y1
Cohen, E1
Mintz, M1
Reddy, DS1
Rogawski, MA1
Edwards, HE1
Vimal, S1
Burnham, WM1
Sarac, MS1
Zieske, AW1
Lindberg, I1
Boggan, WO1
Meyer, JS1
Middaugh, LD1
Sparks, DL1
Goas, JA1
Pelham, RW1
Lippa, AS1
Kakihana, R1
Mcintyre, DC1
D'Mello, SR1
Jiang, C1
Lamberti, C1
Martin, SC1
Heinrich, G1
Chu, HP1
Tombaugh, GC1
Sapolsky, RM1
Rakitskaia, VV1
Garina, IA1
Lopatina, NG1
Pivina, SG1
Shaliapina, VG1
Young, EA1
Spencer, RL1
McEwen, BS1
Lee, PH1
Zhao, DY1
Mitchell, CL1
Hong, JS1
Ferngren, H1
Kershnar, AK1
Roe, TF1
Kogut, MD1
Sze, PY1
Yanai, J1
Ginsburg, BE1
Weltman, AS1
Johnson, L1
Sackler, AM1
Bitter, RA1
Gubler, CJ1
Heninger, RW1

Other Studies

74 other studies available for corticosterone and Seizures

ArticleYear
Sex differences in the developing brain impact stress-induced epileptogenicity following hyperthermia-induced seizures.
    Neurobiology of disease, 2021, Volume: 161

    Topics: Animals; Corticosterone; Female; Humans; Hyperthermia, Induced; Hypothalamo-Hypophyseal System; Male

2021
Toward Evidence-Based Severity Assessment in Mouse Models with Repeated Seizures: (II.) Impact of Surgery and Intrahippocampal Kainate.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2023, Volume: 64, Issue:1

    Topics: Animals; Corticosterone; Disease Models, Animal; Epilepsy; Kainic Acid; Mice; Seizures; Status Epile

2023
Ferulic acid inhibits catamenial epilepsy through modulation of female hormones.
    Metabolic brain disease, 2022, Volume: 37, Issue:8

    Topics: Adult; Animals; Corticosterone; Epilepsy; Estradiol; Female; Finasteride; Horses; Humans; Mice; Neur

2022
Hippocampal glucocorticoid receptors modulate status epilepticus severity.
    Neurobiology of disease, 2023, Volume: 178

    Topics: Animals; Convulsants; Corticosterone; Female; Glucocorticoids; Hippocampus; Male; Mice; Pilocarpine;

2023
Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones.
    Epilepsia, 2023, Volume: 64, Issue:6

    Topics: Animals; Corticosterone; Desoxycorticosterone; Disease Models, Animal; Electroencephalography; Epile

2023
Methyl jasmonate delays the latency to anoxic convulsions by normalizing the brain levels of oxidative stress biomarkers and serum corticosterone contents in mice with repeated anoxic stress.
    Drug metabolism and personalized therapy, 2020, 09-04, Volume: 35, Issue:4

    Topics: Acetates; Animals; Antioxidants; Biomarkers; Brain; Corticosterone; Cyclopentanes; Humans; Male; Mic

2020
Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice.
    Brain research, 2021, 05-01, Volume: 1758

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Brain-Derived Neurotrophic Factor; Convulsants

2021
Neuroinflammation and Neuronal Loss in the Hippocampus Are Associated with Immediate Posttraumatic Seizures and Corticosterone Elevation in Rats.
    International journal of molecular sciences, 2021, May-30, Volume: 22, Issue:11

    Topics: Animals; Biomarkers; Brain Injuries, Traumatic; Cell Count; Cell Death; Corticosterone; Disease Mode

2021
Seizure-induced activation of the HPA axis increases seizure frequency and comorbid depression-like behaviors.
    Epilepsy & behavior : E&B, 2018, Volume: 78

    Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Hypothala

2018
Hyperthermia-induced seizures followed by repetitive stress are associated with age-dependent changes in specific aspects of the mouse stress system.
    Journal of neuroendocrinology, 2019, Volume: 31, Issue:4

    Topics: Adrenal Glands; Aging; Animals; Behavior, Animal; Corticosterone; Female; Hippocampus; Hyperthermia,

2019
Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats.
    Brain research, 2019, 07-01, Volume: 1714

    Topics: Animals; Brain; Cofilin 1; Cognition; Cognition Disorders; Cognitive Dysfunction; Corticosterone; Di

2019
Effects of electroconvulsive seizures on depression-related behavior, memory and neurochemical changes in Wistar and Wistar-Kyoto rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Oct-03, Volume: 54

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Corticotropin-Releasing Hormone;

2014
Effect of pertussis and cholera toxins administered supraspinally on CA3 hippocampal neuronal cell death and the blood glucose level induced by kainic acid in mice.
    Neuroscience research, 2014, Volume: 89

    Topics: Animals; Blood Glucose; CA3 Region, Hippocampal; Cell Death; Cholera Toxin; Corticosterone; Hypergly

2014
Propofol-induced electroencephalographic seizures in neonatal rats: the role of corticosteroids and γ-aminobutyric acid type A receptor-mediated excitation.
    Anesthesia and analgesia, 2015, Volume: 120, Issue:2

    Topics: Adrenal Cortex Hormones; Aldosterone; Anesthetics, Intravenous; Animals; Animals, Newborn; Corticost

2015
Chronic stress shifts the GABA reversal potential in the hippocampus and increases seizure susceptibility.
    Epilepsy research, 2015, Volume: 109

    Topics: Acute Disease; Animals; Bumetanide; Chronic Disease; Corticosterone; Disease Models, Animal; gamma-A

2015
Enhanced susceptibility to seizures modulated by high interleukin-1β levels during early life malnutrition.
    Developmental neurobiology, 2016, Volume: 76, Issue:10

    Topics: Animals; Animals, Newborn; Blotting, Western; Corticosterone; Disks Large Homolog 4 Protein; Enzyme-

2016
Interactive effects of prenatal exposure to restraint stress and alcohol on pentylenetetrazol-induced seizure behaviors in rat offspring.
    Alcohol (Fayetteville, N.Y.), 2016, Volume: 56

    Topics: Animals; Animals, Newborn; Corticosterone; Ethanol; Female; Male; Pentylenetetrazole; Pregnancy; Pre

2016
Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy.
    Neurobiology of disease, 2009, Volume: 34, Issue:3

    Topics: Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Electrodes, Implanted

2009
Effects of low dose neonatal domoic acid administration on behavioural and physiological response to mild stress in adult rats.
    Physiology & behavior, 2009, Aug-04, Volume: 98, Issue:1-2

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Corticosteron

2009
Stress within the postseizure time window inhibits seizure recurrence.
    Epilepsy & behavior : E&B, 2010, Volume: 18, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Anticonvulsants; Circadian Rhythm; Corticos

2010
GABA(A) ρ receptor mechanisms in the rat amygdala and its role in the modulation of fear and anxiety.
    Psychopharmacology, 2010, Volume: 212, Issue:4

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Corticosterone; Dose-Response Relationshi

2010
Predator and restraint stress during gestation facilitates pilocarpine-induced seizures in prepubertal rats.
    Developmental psychobiology, 2011, Volume: 53, Issue:8

    Topics: Animals; Animals, Newborn; Cats; Cholinergic Agents; Corticosterone; Female; Male; Pilocarpine; Pred

2011
Prenatal exposure to restraint or predator stresses attenuates field excitatory postsynaptic potentials in infant rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:8

    Topics: Animals; Corticosterone; Electrophysiology; Excitatory Postsynaptic Potentials; Female; Gestational

2011
Early life stress enhancement of limbic epileptogenesis in adult rats: mechanistic insights.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Amygdala; Animals; CA3 Region, Hippocampal; Cell Count; Corticosterone; Dentate Gyrus; Female; Handl

2011
Pumilio-2 function in the mouse nervous system.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Animals; Body Weight; Brain; Cerebral Cortex; Corticosterone; Electroencephalography; Female; Gene E

2011
Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Corticosterone; Male; Mice; Mice, Inbred C57BL; Pilocarpine; Seiz

2012
The glucose paradox of cerebral ischemia: evidence for corticosterone involvement.
    Brain research, 2003, May-02, Volume: 971, Issue:1

    Topics: Animals; Blood Glucose; Brain; Brain Ischemia; Corticosterone; Electrophysiology; Hormone Antagonist

2003
Neural and hormonal consequences of neonatal 5,7-dihydroxytryptamine may not be associated with serotonin depletion.
    Brain research. Developmental brain research, 2004, Jul-19, Volume: 151, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain Chemistry;

2004
Sex differences in effects of mild chronic stress on seizure risk and GABAA receptors in rats.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:3

    Topics: Animals; Chlorides; Chronic Disease; Corticosterone; Diazepam; Ethanol; Female; Male; Rats; Rats, Sp

2004
Differential effects of mild repeated restraint stress on behaviors and GABA(A) receptors in male and female rats.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:4

    Topics: Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Chlorides; Corticosterone; Female;

2005
Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures.
    Biological psychiatry, 2006, Jan-15, Volume: 59, Issue:2

    Topics: Animals; Antigens; Cell Count; Cell Differentiation; Cell Proliferation; Corticosterone; Depression;

2006
Sex differences in steroid modulation of ethanol withdrawal in male and female rats.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Animals; Corticosterone; Estradiol; Ethanol; Female; Male; Neuroprotective Agents; Ovariectomy; Pent

2007
Neural, endocrine and electroencephalographic hyperreactivity to human contact: a diathesis-stress model of seizure susceptibility in El mice.
    Brain research, 2007, May-04, Volume: 1144

    Topics: Animals; Cell Count; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Diseas

2007
Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice.
    Neuroscience, 2007, May-25, Volume: 146, Issue:3

    Topics: Acute Disease; Animals; Central Nervous System Depressants; Corticosterone; Data Interpretation, Sta

2007
The impact of gonadectomy and adrenalectomy on acute withdrawal severity in male and female C57BL/6J and DBA/2J mice following a single high dose of ethanol.
    Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:11

    Topics: Animals; Central Nervous System Depressants; Corticosterone; Dose-Response Relationship, Drug; Estra

2007
Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice.
    Neuropharmacology, 2008, Volume: 54, Issue:2

    Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Corticosterone; Estradiol; Ethanol; Fe

2008
The neuropharmacological effects of electroconvulsive shock and their relationship to the therapeutic effect of electroconvulsive therapy in depression.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Anesthesia, General; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Brain; Corticost

1984
[Corticosterone content of the blood in Krushinskiĭ-Molodkina and Wistar rats following short-term acoustic exposure].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:11

    Topics: Acoustic Stimulation; Animals; Corticosterone; Male; Rats; Rats, Inbred Strains; Seizures; Time Fact

1981
Cell-specific modulation of basal and seizure-induced neurotrophin expression by adrenalectomy.
    Neuroscience, 1995, Volume: 68, Issue:2

    Topics: Adrenalectomy; Animals; Brain-Derived Neurotrophic Factor; Corticosterone; In Situ Hybridization; Ma

1995
Down-regulation of the hypothalamo-pituitary-adrenal axis reduces brain damage and number of seizures following hypoxia/ischaemia in rats.
    Brain research, 1995, Aug-28, Volume: 690, Issue:1

    Topics: Adrenal Glands; Animals; Brain Damage, Chronic; Corticosterone; Down-Regulation; Hypothalamo-Hypophy

1995
ACTH does not control neonatal seizures induced by administration of exogenous corticotropin-releasing hormone.
    Epilepsia, 1995, Volume: 36, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Corticotropin-Releasing Hormone; Disease Model

1995
Sensitivity of the circadian rhythm of kainic acid-induced convulsion susceptibility to manipulations of corticosterone levels and mineralocorticoid receptor binding.
    Neuropharmacology, 1994, Volume: 33, Issue:9

    Topics: Animals; Circadian Rhythm; Corticosterone; Hippocampus; Kainic Acid; Male; Mice; Mineralocorticoid R

1994
Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice.
    Psychopharmacology, 1994, Volume: 115, Issue:1-2

    Topics: Animals; Behavior, Animal; Corticosterone; Diazepam; Ethanol; Female; Flumazenil; Handling, Psycholo

1994
The effect of corticosterone in rats submitted to the elevated plus-maze and to to pentylenetetrazol-induced convulsions.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:8

    Topics: Administration, Cutaneous; Animals; Anti-Anxiety Agents; Corticosterone; Dose-Response Relationship,

1994
Effects of aging on acute toxicity of nicotine in rats.
    Pharmacology & toxicology, 1994, Volume: 75, Issue:1

    Topics: Aging; Animals; Brain; Corticosterone; Cytochrome P-450 Enzyme System; Dopamine; Injections, Intrape

1994
Mineralocorticoid receptors mediate the enhancing effects of corticosterone on convulsion susceptibility in mice.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2

    Topics: Animals; Corticosterone; Disease Susceptibility; Kainic Acid; Male; Mice; Mice, Inbred Strains; Pent

1994
Facilitation of cocaine kindling by glucocorticoids in rats.
    Brain research, 1993, Nov-26, Volume: 629, Issue:1

    Topics: Animals; Cocaine; Corticosterone; Dexamethasone; Drug Synergism; Kindling, Neurologic; Male; Motor A

1993
Effects of water immersion stress on convulsions induced by pentylenetetrazol.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Animals; Corticosterone; Immersion; Male; Pentylenetetrazole; Radioimmunoassay; Rats; Rats, Sprague-

1993
Kinetics of drug action in disease states. XLI. Effect of adrenalectomy on the hypnotic activity of phenobarbital, the neurotoxicity of theophylline and pain sensitivity in rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Adrenalectomy; Animals; Blood Proteins; Corticosterone; Male; Pain; Pain Threshold; Phenobarbital; R

1993
Adrenal steroids mediate the increase of hippocampal nerve growth factor biosynthesis following bicuculline convulsions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Bicuculline; Blotting, Northern; Corticosterone; De

1993
Anxiolytic-like effects of PNU-101017, a partial agonist at the benzodiazepine receptor.
    Psychopharmacology, 1997, Volume: 131, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Cells, Cultured; Cerebellum; Conflict, Psychologic

1997
Prenatal stress reduces the effectiveness of the neurosteroid 3 alpha,5 alpha-THP to block kainic-acid-induced seizures.
    Developmental psychobiology, 1999, Volume: 34, Issue:3

    Topics: Analysis of Variance; Animals; Anticonvulsants; Corticosterone; Female; gamma-Aminobutyric Acid; Hip

1999
Differential impact of predator or immobilization stressors on central corticotropin-releasing hormone and bombesin-like peptides in Fast and Slow seizing rat.
    Brain research, 2001, Jul-06, Volume: 906, Issue:1-2

    Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Bombesin; Corticosterone; Corticotropin-Releasing Ho

2001
Social attraction between rats in open field: long-term consequences of kindled seizures.
    Brain research, 2001, Dec-13, Volume: 922, Issue:1

    Topics: Amygdala; Animals; Anxiety; Corticosterone; Electric Stimulation; Electrodes, Implanted; Emotions; E

2001
Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9

    Topics: 5-alpha Reductase Inhibitors; Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Convu

2002
The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats.
    Experimental neurology, 2002, Volume: 175, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Dehydroepiandrosterone; Desoxycor

2002
The lethal form of Cushing's in 7B2 null mice is caused by multiple metabolic and hormonal abnormalities.
    Endocrinology, 2002, Volume: 143, Issue:6

    Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Cause of Death; Corticosterone; Cushing Syndrom

2002
Ethanol, calcium, and naloxone in mice.
    Alcoholism, clinical and experimental research, 1979, Volume: 3, Issue:2

    Topics: Animals; Brain; Calcium; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Ethano

1979
Endocrine factors contributing to the ethanol preferences of rodents.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:4

    Topics: Alcohol Drinking; Animals; Blood Glucose; Choice Behavior; Corticosterone; Cricetinae; Cricetulus; E

1979
Alcohol intoxication and withdrawal in inbred strains of mice: behavioral and endocrine studies.
    Behavioral and neural biology, 1979, Volume: 26, Issue:1

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Corticosterone; Ethanol; Genotype; Hu

1979
Adrenalectomy: protection from kindled convulsion induced amnesia in rats.
    Physiology & behavior, 1976, Volume: 17, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Amnesia; Amnesia, Retrograde; Amygdala; Animals; Avoidance Learning;

1976
Effects of acute administration of nicotine on convulsive movements and blood levels of corticosterone in old rats.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:4

    Topics: Aging; Animals; Corticosterone; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Injections

1992
Genetic differences in hypothalamic-pituitary-adrenal axis responsiveness to acute ethanol and acute ethanol withdrawal.
    Brain research, 1992, May-08, Volume: 579, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Ethanol; Handling, Psychological; Hypothalamo-

1992
Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts.
    Journal of neuroscience research, 1992, Volume: 33, Issue:4

    Topics: Animals; Base Sequence; Blotting, Northern; Brain-Derived Neurotrophic Factor; Colforsin; Corticoste

1992
Differential modulation by the stress axis of ethanol withdrawal seizure expression in WSP and WSR mice.
    Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:3

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Arousal; Corticosterone; Handling, Psychological;

1991
Hippocampal glutamine synthetase: insensitivity to glucocorticoids and stress.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: Adrenalectomy; Animals; Corticosterone; Glutamate-Ammonia Ligase; Hippocampus; Kainic Acid; Male; Mu

1990
[The receptor binding of 3H-corticosterone and the dopamine content in the striatum of rats with a predisposition to audiogenic seizures].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1990, Volume: 76, Issue:6

    Topics: Acoustic Stimulation; Animals; Corpus Striatum; Corticosterone; Disease Susceptibility; Dopamine; No

1990
Changes at multiple levels of the hypothalamo-pituitary adrenal axis following repeated electrically induced seizures.
    Psychoneuroendocrinology, 1990, Volume: 15, Issue:3

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Brain Chemistry; Corticosterone

1990
Effects of corticosterone on shaking and seizure behavior induced by deep prepyriform cortex kindling.
    Neuroscience letters, 1987, Dec-04, Volume: 82, Issue:3

    Topics: Adrenalectomy; Animals; Behavior, Animal; Cerebral Cortex; Corticosterone; Kindling, Neurologic; Mal

1987
High frequency electro-shock seizures and their antagonism in developing mice. 3. Effects of cortisol, corticosterone, deoxycorticosterone, dexamethasone and a synthetic corticotropine.
    Acta pharmaceutica Suecica, 1969, Volume: 6, Issue:3

    Topics: Adrenocorticotropic Hormone; Age Factors; Animals; Corticosterone; Dexamethasone; Electroshock; Hydr

1969
Adrenocorticotropic hormone unresponsiveness: report of a girl with excessive growth and review of 16 reported cases.
    The Journal of pediatrics, 1972, Volume: 80, Issue:4

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aldosterone; Arginine; Child; Corticoster

1972
Adrenal glucocorticoids as a required factor in the development of ethanol withdrawal seizures in mice.
    Brain research, 1974, Nov-08, Volume: 80, Issue:1

    Topics: Adrenal Glands; Alcoholic Intoxication; Animals; Corticosterone; Humans; Male; Mice; Mice, Inbred St

1974
Behavioral and adrenal relationships to audiogenic-seizure susceptibility in BALB-cJ mice.
    Life sciences, 1974, Feb-16, Volume: 14, Issue:4

    Topics: Acoustic Stimulation; Adrenal Glands; Animals; Behavior, Animal; Body Weight; Corticosterone; Defeca

1974
Effects of forced-feeding on blood levels of pyruvate, glucocorticoids and glucose and on adrenal weight in thiamine-deprived and thiamine antagonist-treated rats.
    The Journal of nutrition, 1969, Volume: 98, Issue:2

    Topics: Adrenal Glands; Animals; Ataxia; Blood Glucose; Corticosterone; Diet; Feeding and Eating Disorders;

1969