Page last updated: 2024-11-05

urethane and Seizures

urethane has been researched along with Seizures in 21 studies

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"The present experiments examined whether pretreatment with the noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists, MK-801 and dextrorphan, could antagonize cocaine-induced convulsions and lethality in conscious Sprague-Dawley (SD) rats and whether urethane anesthesia alters the observed interactions."7.69Urethane anesthesia reverses the protective effect of noncompetitive NMDA receptor antagonists against cocaine intoxication. ( Bennett, JG; Byrne, M; Rockhold, RW; Sprabery, S, 1994)
"The effect of low doses of urethane on three phases of spinal seizures evoked by sudden cooling (SSSC) of toad isolated spinal cord was studied."7.68Low doses of urethane effectively inhibit spinal seizures evoked by sudden cooling of toad isolated spinal cord. ( Daló, NL; Piña-Crespo, JC, 1992)
"The effect of anesthetic and subanesthetic doses of urethane on the development of amygdala kindled seizures and on the expression of previously kindled seizures was studied in hooded rats."7.67Urethane anesthesia blocks the development and expression of kindled seizures. ( Cain, DP; Corcoran, ME; Raithby, A, 1989)
"The present experiments examined whether pretreatment with the noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists, MK-801 and dextrorphan, could antagonize cocaine-induced convulsions and lethality in conscious Sprague-Dawley (SD) rats and whether urethane anesthesia alters the observed interactions."3.69Urethane anesthesia reverses the protective effect of noncompetitive NMDA receptor antagonists against cocaine intoxication. ( Bennett, JG; Byrne, M; Rockhold, RW; Sprabery, S, 1994)
"The effect of low doses of urethane on three phases of spinal seizures evoked by sudden cooling (SSSC) of toad isolated spinal cord was studied."3.68Low doses of urethane effectively inhibit spinal seizures evoked by sudden cooling of toad isolated spinal cord. ( Daló, NL; Piña-Crespo, JC, 1992)
"The effect of anesthetic and subanesthetic doses of urethane on the development of amygdala kindled seizures and on the expression of previously kindled seizures was studied in hooded rats."3.67Urethane anesthesia blocks the development and expression of kindled seizures. ( Cain, DP; Corcoran, ME; Raithby, A, 1989)
"Autonomic dysfunction during seizures can induce bradyarrhythmia via efferent vagal overactivity."1.36Efferent and afferent vagal actions on cortical blood flow and kainic acid-induced seizure activity in urethane anesthetized rats. ( Hotta, H; Orman, R; Stewart, M; Watanabe, N, 2010)
"Motor seizures provoked in kindled rats were associated with intense and prolonged spike bursts followed by spikeless positive waves recorded in the granule cell layer of fascia dentata."1.27Sustained potential shifts and paroxysmal discharges in hippocampal formation. ( Aitken, PG; Giacchino, JL; McNamara, JO; Somjen, GG, 1985)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199015 (71.43)18.7374
1990's2 (9.52)18.2507
2000's1 (4.76)29.6817
2010's1 (4.76)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Kurki, SN1
Ala-Kurikka, T1
Lipponen, A1
Pospelov, AS1
Rolova, T1
Koistinaho, J1
Voipio, J1
Kaila, K1
Rojas, A1
Wang, J1
Glover, A1
Dingledine, R1
Hotta, H1
Watanabe, N1
Orman, R1
Stewart, M2
SCHOETENSACK, W1
HALLMANN, G1
Saito, T1
Sakamoto, K1
Koizumi, K1
Takeda, M1
Yoshimura, H1
Tsukamoto, H1
Ricci, GF1
Cherubini, E1
de Feo, MR1
Mecarelli, O1
Kornet, MJ1
Rockhold, RW1
Byrne, M1
Sprabery, S1
Bennett, JG1
Greenberg, R1
Smorong, K1
Piña-Crespo, JC1
Daló, NL1
Suzuki, SS1
Smith, GK1
Cain, DP1
Raithby, A1
Corcoran, ME1
Kapur, J1
Lothman, EW1
Somjen, GG1
Aitken, PG1
Giacchino, JL1
McNamara, JO1
Angel, A1
Lemon, RN1
Murmann, W1
Almirante, L1
Saccani-Guelfi, M1
Tannhauser, M1
Izquierdo, I1
Moussatché, H1
Cuadra, JL1
Prasad, S1
Malhotra, CL1
Bean, JW1
Zee, D1

Other Studies

21 other studies available for urethane and Seizures

ArticleYear
A brain cytokine-independent switch in cortical activity marks the onset of sickness behavior triggered by acute peripheral inflammation.
    Journal of neuroinflammation, 2023, Jul-28, Volume: 20, Issue:1

    Topics: Animals; Brain; Cytokines; Illness Behavior; Inflammation; Lipopolysaccharides; Mice; Seizures; Uret

2023
Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats.
    Neurobiology of disease, 2020, Volume: 140

    Topics: Acetylcholinesterase; Animals; Brain Injuries; Diazepam; Disease Models, Animal; Electroencephalogra

2020
Efferent and afferent vagal actions on cortical blood flow and kainic acid-induced seizure activity in urethane anesthetized rats.
    Autonomic neuroscience : basic & clinical, 2010, Aug-25, Volume: 156, Issue:1-2

    Topics: Animals; Blood Flow Velocity; Cerebral Cortex; Cerebrovascular Circulation; Kainic Acid; Male; Neuro

2010
[VERATRAMINE EXCITATION AND ITS PHARMACOLOGICAL CONTROL].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Decerebrate State; Mice; Muscle Relaxants, Central; Pharmacology; Rats; Research; Seizures; Tremor;

1964
Repeatable focal seizure suppression: a rat preparation to study consequences of seizure activity based on urethane anesthesia and reversible carotid artery occlusion.
    Journal of neuroscience methods, 2006, Sep-15, Volume: 155, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Arterial Occlusive Diseases; Blood Pressure; Carotid Artery Disea

2006
[Metabolism of drugs. LIV. On the pharmacological action of carbamate N-glucuronides].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1966, Volume: 86, Issue:12

    Topics: Animals; Carbamates; Coma; Glucuronates; Male; Meprobamate; Mice; Pentobarbital; Rats; Seizures; Ure

1966
Development of epileptic activity and its correlation with GABAergic and glutamergic systems during brain maturation in the rat.
    Progress in clinical and biological research, 1983, Volume: 124

    Topics: Action Potentials; Animals; Behavior, Animal; Brain; Diazepam; Electrophysiology; gamma-Aminobutyric

1983
Synthesis of phenylurethans of 1,2-dialkyl-4-pyrazolidinols as anticonvulsant agents.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:6

    Topics: Animals; Anticonvulsants; Carbamates; Drug Evaluation, Preclinical; Male; Mice; Nervous System; Phen

1980
Urethane anesthesia reverses the protective effect of noncompetitive NMDA receptor antagonists against cocaine intoxication.
    Life sciences, 1994, Volume: 54, Issue:5

    Topics: Anesthesia; Animals; Blood Pressure; Body Temperature; Cocaine; Consciousness; Dextrorphan; Dizocilp

1994
The bronchodilator acitivity of an 11-deoxyprostaglandin (AY 23 578).
    Canadian journal of physiology and pharmacology, 1975, Volume: 53, Issue:5

    Topics: Aerosols; Animals; Bronchodilator Agents; Carbachol; Cats; Dose-Response Relationship, Drug; Guinea

1975
Low doses of urethane effectively inhibit spinal seizures evoked by sudden cooling of toad isolated spinal cord.
    Life sciences, 1992, Volume: 51, Issue:7

    Topics: Animals; Bufo marinus; Cold Temperature; In Vitro Techniques; Muscle Contraction; Seizures; Spinal C

1992
Spontaneous EEG spikes in the normal hippocampus. V. Effects of ether, urethane, pentobarbital, atropine, diazepam and bicuculline.
    Electroencephalography and clinical neurophysiology, 1988, Volume: 70, Issue:1

    Topics: Anesthetics; Animals; Atropine; Behavior, Animal; Bicuculline; Diazepam; Electroencephalography; Eth

1988
Urethane anesthesia blocks the development and expression of kindled seizures.
    Life sciences, 1989, Volume: 44, Issue:17

    Topics: Anesthesia, General; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Kindling, Neur

1989
Loss of inhibition precedes delayed spontaneous seizures in the hippocampus after tetanic electrical stimulation.
    Journal of neurophysiology, 1989, Volume: 61, Issue:2

    Topics: Anesthesia; Animals; Electric Stimulation; Electrophysiology; Hippocampus; Male; Neural Inhibition;

1989
Sustained potential shifts and paroxysmal discharges in hippocampal formation.
    Journal of neurophysiology, 1985, Volume: 53, Issue:4

    Topics: Anesthesia; Animals; Consciousness; Differential Threshold; Electrophysiology; Granulocytes; Hippoca

1985
The convulsive action of 1,2-dihydroxybenzene in the anaesthetized rat.
    Electroencephalography and clinical neurophysiology, 1973, Volume: 34, Issue:4

    Topics: Anesthesia; Animals; Body Temperature; Catechols; Cerebellum; Cerebral Cortex; Cerebral Decorticatio

1973
Effects of hexobarbitone, ether, morphine, and urethane upon the acute toxicity of propranolol and D-(--)-INPEA.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:10

    Topics: Amino Alcohols; Animals; Atropine; Bradycardia; Central Nervous System; Drug Synergism; Ethers; Hear

1966
Effect of seizures and anticonvulsant agents on hippocampal RNA concentration.
    Pharmacology, 1974, Volume: 11, Issue:3

    Topics: Anesthesia, General; Animals; Anticonvulsants; Cannabis; Cerebral Cortex; Depression, Chemical; Elec

1974
Some pharmacological studies on cryoepilepsy. I. Preliminary report for quantitative studies.
    Revista brasileira de biologia, 1967, Volume: 27, Issue:1

    Topics: Animals; Anura; Body Weight; Cold Temperature; Seizures; Urethane

1967
Studies on Withania ashwagandha Kaul. VI. The effect of the alkaloidal fractions (acetone, alcohol and water soluble) on the central nervous system.
    Indian journal of physiology and pharmacology, 1968, Volume: 12, Issue:4

    Topics: Acetone; Alkaloids; Animals; Behavior, Animal; Body Temperature; Central Nervous System; Drug Synerg

1968
Influence of anesthesia and CO2 on CNS and pulmonary effects of O2 at high pressure.
    Journal of applied physiology, 1966, Volume: 21, Issue:2

    Topics: Animals; Carbon Dioxide; Central Nervous System; Chloralose; Hyperbaric Oxygenation; Lung; Oxygen; P

1966