8-(4-sulfophenyl)theophylline has been researched along with Seizures in 4 studies
8-(4-sulfophenyl)theophylline: adenosine antagonist
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kainic acid (KA), microinjected unilaterally into the rat prepiriform cortex (PC), produces generalized motor seizures in a dose-dependent manner." | 7.68 | Anticonvulsant effect of N-ethylcarboxamidoadenosine against kainic acid-induced behavioral seizures in the rat prepiriform cortex. ( Franklin, PH; Murray, TF; Zhang, G, 1990) |
| "4 nmol) against bicuculline methiodide-induced seizures, and these anticonvulsant effects were significantly potentiated by treatment with an adenosine kinase inhibitor, 5'-amino-5'-deoxyadenosine; by the adenosine transport blockers, dilazep or nitrobenzylthioinosine 5'-monophosphate; and by an adenosine deaminase inhibitor, 2'-deoxycoformycin." | 3.68 | Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility. ( Franklin, PH; Murray, TF; Zhang, G, 1993) |
| "Kainic acid (KA), microinjected unilaterally into the rat prepiriform cortex (PC), produces generalized motor seizures in a dose-dependent manner." | 3.68 | Anticonvulsant effect of N-ethylcarboxamidoadenosine against kainic acid-induced behavioral seizures in the rat prepiriform cortex. ( Franklin, PH; Murray, TF; Zhang, G, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borowicz, K | 1 |
| Kozicka, M | 1 |
| Kleinrok, Z | 1 |
| Czuczwar, SJ | 1 |
| Zhang, G | 2 |
| Franklin, PH | 2 |
| Murray, TF | 2 |
| Whitcomb, K | 1 |
| Lupica, CR | 1 |
| Rosen, JB | 1 |
| Berman, RF | 1 |
4 other studies available for 8-(4-sulfophenyl)theophylline and Seizures
| Article | Year |
|---|---|
Influence of aminophylline and 8-(p-sulfophenyl)theophylline on the anticonvulsive action of diphenylhydantoin, phenobarbital, and valproate against maximal electroshock-induced convulsions in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mice; | 1993 |
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Animals; Bicucul | 1993 |
Adenosine involvement in postictal events in amygdala-kindled rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amygdala; Animals; Anticonvulsants; Caffeine; Electric | 1990 |
Anticonvulsant effect of N-ethylcarboxamidoadenosine against kainic acid-induced behavioral seizures in the rat prepiriform cortex.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dilazep; Kainic Acid; Limbic System; Male; Ra | 1990 |