acetamide has been researched along with Seizures in 4 studies
acetimidic acid : A carboximidic acid that is acetic acid in which the carbonyl oxygen is replaced by an imino group.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The compound had a pronounced anticonvulsant effect, significantly reducing the mortality of mice in models of seizures induced by pentylenetetrazole, picrotoxin, strychnine, and caffeine." | 4.12 | Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico. ( Georgiyants, V; Kayal, WE; Mishchenko, M; Severina, H; Shtrygol, D; Shtrygol, S; Zalevskyi, S, 2022) |
| "In the thiosemicarbazideinduced seizure model, the test compound did not reduce mortality." | 1.72 | Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico. ( Georgiyants, V; Kayal, WE; Mishchenko, M; Severina, H; Shtrygol, D; Shtrygol, S; Zalevskyi, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shtrygol, S | 3 |
| Zalevskyi, S | 3 |
| Mishchenko, M | 3 |
| Shtrygol, D | 3 |
| Severina, H | 3 |
| Kayal, WE | 3 |
| Georgiyants, V | 3 |
| Chauhan, D | 1 |
| Hashim, SR | 1 |
| Rani, P | 1 |
| Kumar, S | 1 |
| Shrimal, N | 1 |
| Shastri, D | 1 |
| Raj, V | 1 |
| El Kayal, WM | 1 |
| Shtrygol, SY | 1 |
| Zalevskyi, SV | 1 |
| Shark, AA | 1 |
| Tsyvunin, VV | 1 |
| Kovalenko, SM | 1 |
| Bunyatyan, ND | 1 |
| Perekhoda, LO | 1 |
| Severina, HI | 1 |
| Georgiyants, VA | 1 |
| Gorniak, SL | 1 |
| Palermo-Neto, J | 1 |
| Spinosa, HS | 1 |
4 other studies available for acetamide and Seizures
| Article | Year |
|---|---|
Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico.
Topics: Acetamides; Action Spectrum; Animals; Anticonvulsants; Caffeine; gamma-Aminobutyric Acid; Mice; Mole | 2022 |
Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico.
Topics: Acetamides; Action Spectrum; Animals; Anticonvulsants; Caffeine; gamma-Aminobutyric Acid; Mice; Mole | 2022 |
Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico.
Topics: Acetamides; Action Spectrum; Animals; Anticonvulsants; Caffeine; gamma-Aminobutyric Acid; Mice; Mole | 2022 |
Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico.
Topics: Acetamides; Action Spectrum; Animals; Anticonvulsants; Caffeine; gamma-Aminobutyric Acid; Mice; Mole | 2022 |
Discovery of Substituted N-(6-Chloro-3-cyano-4-phenyl-4H-chromen-2-yl)- 2-(4-chloro-phenoxy)-acetamide for Biphasic Anticancer and Anticonvulsant Activities.
Topics: Acetamides; Animals; Anticonvulsants; Antineoplastic Agents; Cell Proliferation; Dose-Response Relat | 2021 |
Synthesis, in vivo and in silico anticonvulsant activity studies of new derivatives of 2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)acetamide.
Topics: Acetamides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Female; Male; Mice; Microbia | 2019 |
Effects of acetamide on experimentally-induced Palicourea marcgravii (St Hill) poisoning in rats.
Topics: Acetamides; Animals; Antidotes; Fluoroacetates; Male; Plant Poisoning; Rats; Rats, Wistar; Seizures | 1994 |