ritanserin has been researched along with Seizures in 4 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Convulsions were followed by statistically significant increase in the tail-flick latencies (TFL), at least for 120 min of the post-ictal period." | 1.33 | Involvement of 5-HT(2) serotonergic receptors of the nucleus raphe magnus and nucleus reticularis gigantocellularis/paragigantocellularis complex neural networks in the antinociceptive phenomenon that follows the post-ictal immobility syndrome. ( Coimbra, NC; de Oliveira, R; de Oliveira, RC; Ferreira, CM, 2006) |
| "When tryptamine was preceded by an apomorphine challenge the effective doses of the 5-HT2 antagonists ritanserin and risperidone for 50% inhibition of the seizures increased by a factor of 2." | 1.28 | Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine. ( Awouters, F; Janssen, PA; Megens, AA; Niemegeers, CJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Barba, C | 1 |
| Medina-Ceja, L | 1 |
| de Oliveira, RC | 1 |
| de Oliveira, R | 1 |
| Ferreira, CM | 1 |
| Coimbra, NC | 1 |
| Williams, MB | 1 |
| Jope, RS | 1 |
| Awouters, F | 1 |
| Niemegeers, CJ | 1 |
| Megens, AA | 1 |
| Janssen, PA | 1 |
4 other studies available for ritanserin and Seizures
| Article | Year |
|---|---|
Serotonin receptor antagonists increase fast ripple activity in rats treated with kainic acid.
Topics: Analysis of Variance; Animals; Brain Waves; Dose-Response Relationship, Drug; Electroencephalography | 2016 |
Involvement of 5-HT(2) serotonergic receptors of the nucleus raphe magnus and nucleus reticularis gigantocellularis/paragigantocellularis complex neural networks in the antinociceptive phenomenon that follows the post-ictal immobility syndrome.
Topics: Analgesia; Analysis of Variance; Animals; Behavior, Animal; Brain; Male; Medulla Oblongata; Models, | 2006 |
Lithium potentiates phosphoinositide-linked 5-HT receptor stimulation in vivo.
Topics: Amphetamines; Animals; Drug Synergism; Genes, fos; Lithium; Male; Phosphatidylinositols; Rats; Rats, | 1994 |
Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Drug Interac | 1990 |