Compounds > preprotachykinin b (50-79)
Page last updated: 2024-11-12

preprotachykinin b (50-79)

Description

preprotachykinin B (50-79): amino acid sequence given in first source; found in both neurokinin B and preprotachykinin B [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16131046
MeSH IDM0214324

Synonyms (8)

Synonym
l-leucyl-l-tyrosyl-l-alpha-aspartyl-l-seryl-l-arginyl-l-seryl-l-isoleucyl-l-seryl-l-leucyl-l-alpha-glutamylglycyl-l-leucyl-l-leucyl-l-lysyl-l-valyl-l-leucyl-l-seryl-l-lysyl-l-alanyl-l-seryl-l-valylglycyl-l-prolyl-l-lysyl-l-alpha-glutamyl-l-threonyl-l-sery
preprotachykinin b (50-79)
nkb peptide 2
nkb-p2
148597-04-0
l-glutamine, l-leucyl-l-tyrosyl-l-alpha-aspartyl-l-seryl-l-arginyl-l-seryl-l-isoleucyl-l-seryl-l-leucyl-l-alpha-glutamylglycyl-l-leucyl-l-leucyl-l-lysyl-l-valyl-l-leucyl-l-seryl-l-lysyl-l-alanyl-l-seryl-l-valylglycyl-l-prolyl-l-lysyl-l-alpha-glutamyl-l-th
peptide 2, neurokinin b
DTXSID70164027
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.41 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
kainic acid
Kainic Acid: (2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.		1.9810dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist
substance p
[no description available]		210peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
enkephalin, leucine
Enkephalin, Leucine: One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.. Leu-enkephalin : A pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties.		2.4220pentapeptide;
peptide zwitterion		analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite
neurokinin b
Neurokinin B: A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ A with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the URINARY BLADDER and UTERUS.		3.2560polypeptide
dynorphins
Dynorphins: A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.		2.4220
preproenkephalin
preproenkephalin: initial enkephalin precursor		2.4220
ConditionIndicatedRelationship StrengthStudiesTrials
Absence Seizure
[description not available]		01.9810
Seizures
Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.		01.9810
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