| Assay ID | Title | Year | Journal | Article |
|---|
| AID1359347 | Increase in MITF mRNA expression in mouse Melan-a cells at 40 uM after 24 hrs by SYBR green dye based qRT-PCR analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1105461 | Antifungal activity against Aspergillus fumigatus ATCC 16913 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID1359367 | Agonist activity at ERbeta in mouse Melan-a cells assessed as increase in melanin content at 40 uM measured after 48 hrs in presence of ER antagonist ICI 182780 | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1347662 | Antiproliferative activity against human MCF7 cells at 1 nM to 100 uM after 24 hrs by MTT assay relative to control | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. |
| AID1359365 | Photostability of the compound assessed as compound degradation under sunlight exposed for 6 days in EtOH solution measured in presence of UV-A filter Uvinul A by TLC method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID659710 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 0.1 uM after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID1347664 | Antiproliferative activity against human MDA-MB-231 cells at 1 nM to 100 uM after 24 hrs by MTT assay relative to control | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. |
| AID1357271 | Anti-parkinson's activity in intranigral LPS-induced Parkinson's disease-like C57BL/6 mouse model assessed as inhibition of microglial hyperactivation by measuring IBA1 positive cells at 19.3 mg/kg, sc once daily for 21 days starting from day 1 post LPS t | 2018 | European journal of medicinal chemistry, Jun-10, Volume: 153 | Recent acquisitions on oxyprenylated secondary metabolites as anti-inflammatory agents. |
| AID1429913 | Growth inhibition of human LoVo cells after 24 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity. |
| AID449580 | Anticonvulsant activity in mouse after 60 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID1359359 | Increase in TRP2 expression in mouse Melan-a cells at 40 uM after 72 hrs by Western blot analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1359345 | Increase in TRP1 mRNA expression in mouse Melan-a cells at 40 uM after 24 hrs by SYBR green dye based qRT-PCR analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID376064 | Antimutagenic activity in Salmonella Typhimurium TA102 assessed as protection against hydrogen peroxide-induced mutation at 4 ug/plate after 2 days by modified Ames test | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10
| Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations. |
| AID449576 | Anticonvulsant activity in mouse at 300 mg/kg, ip after 120 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID1376904 | Antagonist activity at AhR (unknown origin) expressed in mouse H1L1.1c2 cells assessed as inhibition of FICZ-induced AhR activation at 1 to 100 uM after 8 to 10 hrs by luciferase reporter gene assay | 2017 | Journal of natural products, 06-23, Volume: 80, Issue:6
| Interaction of 7-Alkoxycoumarins with the Aryl Hydrocarbon Receptor. |
| AID1359342 | Induction of melanogenesis in mouse Melan-a cells assessed as effect on pigmentation at 40 uM after 72 hrs by photography | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID449573 | Anticonvulsant activity in mouse at 300 mg/kg, ip after 15 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID1163511 | Cytotoxicity against human PANC1 cells under nutrient-rich condition after 24 hrs by WST8 dye based assay | 2014 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 24, Issue:19
| Synthesis and biological evaluation of isoprenylated coumarins as potential anti-pancreatic cancer agents. |
| AID376058 | Antimutagenic activity in Salmonella Typhimurium TA100 assessed as protection against benzo[a]pyrene-induced mutation at 8 ug/plate after 2 days by modified Ames test | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10
| Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations. |
| AID607593 | Cytotoxicity against human U373 cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID1429914 | Growth inhibition of human LoVo/DX cells after 24 hrs by MTT assay | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity. |
| AID1347661 | Antiproliferative activity against human BT549 cells after 24 hrs by MTT assay | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. |
| AID376063 | Antimutagenic activity in Salmonella Typhimurium TA102 assessed as protection against hydrogen peroxide-induced mutation at 2 ug/plate after 2 days by modified Ames test | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10
| Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations. |
| AID607598 | Cytotoxicity against human LoVo cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID1429931 | Inhibition of P-gp in human LoVo/DX cells assessed as reduction in Rhodamine123 efflux at 2.5 uM preincubated for 15 mins followed by Rhodamine123 addition measured after 1 hr by flow cytometry | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity. |
| AID1359360 | Increase in MITF expression in mouse Melan-a cells at 40 uM after 72 hrs by Western blot analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1359357 | Increase in tyrosinase expression in mouse Melan-a cells at 40 uM after 72 hrs by Western blot analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID376056 | Antimutagenic activity in Salmonella Typhimurium TA100 assessed as protection against benzo[a]pyrene-induced mutation at 2 ug/plate after 2 days by modified Ames test | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10
| Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations. |
| AID659712 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 5 uM after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID1359338 | Induction of melanogenesis in mouse Melan-a cells assessed as increase in melanin content at 40 uM | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID659713 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 10 uM after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID449577 | Anticonvulsant activity in mouse after 5 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID1105460 | Antifungal activity against Aspergillus fumigatus IPP 210 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID607600 | Induction of human U373 cell death assessed as morphological changes at MTT assay-related IC50 after 72 hrs by quantitative video microscopy | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID1105454 | Antifungal activity against Aspergillus flavus LM 26 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID1163510 | Cytotoxicity against human PANC1 cells under nutrient-deprived condition after 24 hrs by WST8 dye based assay | 2014 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 24, Issue:19
| Synthesis and biological evaluation of isoprenylated coumarins as potential anti-pancreatic cancer agents. |
| AID1376902 | Agonist activity at AhR (unknown origin) expressed in mouse H1L1.1c2 cells after 8 to 10 hrs by luciferase reporter gene assay | 2017 | Journal of natural products, 06-23, Volume: 80, Issue:6
| Interaction of 7-Alkoxycoumarins with the Aryl Hydrocarbon Receptor. |
| AID659717 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID1347665 | Antiproliferative activity against human BT549 cells at 1 nM to 100 uM after 24 hrs by MTT assay relative to control | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. |
| AID449572 | Anticonvulsant activity in mouse at 300 mg/kg, ip after 5 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID449574 | Anticonvulsant activity in mouse at 300 mg/kg, ip after 30 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID622344 | Cytotoxicity against human PANC1 cells in nutrient-rich condition assessed as cell death up to 200 uM after 24 hrs by WST-8 assay | 2011 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 21, Issue:19
| Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative. |
| AID1347657 | Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell lysates after 1 hr by gamma counting analysis | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. |
| AID659711 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 1 uM after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID659715 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 50 uM after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID1359335 | Induction of melanogenesis in mouse Melan-a cells assessed as increase in melanin content at 10 to 40 uM after 48 hrs | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1105457 | Antifungal activity against Aspergillus flavus LM 247 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID1359346 | Increase in TRP2 mRNA expression in mouse Melan-a cells at 40 uM after 24 hrs by SYBR green dye based qRT-PCR analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID659714 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 25 uM after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID376057 | Antimutagenic activity in Salmonella Typhimurium TA100 assessed as protection against benzo[a]pyrene-induced mutation at 4 ug/plate after 2 days by modified Ames test | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10
| Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations. |
| AID1359364 | Photostability of the compound assessed as compound degradation under sunlight exposed for 6 days in EtOH solution measured by TLC method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1105456 | Antifungal activity against Aspergillus flavus ATCC 16013 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID1359361 | Increase in Rab27a expression in mouse Melan-a cells at 40 uM after 72 hrs by Western blot analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1357273 | Anti-parkinson's activity in intranigral LPS-induced Parkinson's disease-like C57BL/6 mouse model assessed as astrocytes activation at 19.3 mg/kg, sc once daily for 21 days starting from day 1 post LPS treatment by confocal fluorescence microscopic method | 2018 | European journal of medicinal chemistry, Jun-10, Volume: 153 | Recent acquisitions on oxyprenylated secondary metabolites as anti-inflammatory agents. |
| AID1347663 | Antiproliferative activity against mouse mammary carcinoma cell at 1 nM to 100 uM after 24 hrs by MTT assay relative to control | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. |
| AID659716 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 100 uM after 24 hrs by dual-luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. |
| AID449581 | Muscle relaxant activity in rat thoracic aorta assessed as inhibition of KCl-induced contraction at 100 uM | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID1357275 | Anti-parkinson's activity in intranigral LPS-induced Parkinson's disease-like C57BL/6 mouse model assessed as protection against dopaminergic neuronal loss in substantia nigra by measuring increase in TH-positive neuronal cells at 19.3 mg/kg, sc once dail | 2018 | European journal of medicinal chemistry, Jun-10, Volume: 153 | Recent acquisitions on oxyprenylated secondary metabolites as anti-inflammatory agents. |
| AID622341 | Cytotoxicity against human PANC1 cells in nutrient-deprived condition assessed as cell death at 100 uM after 24 hrs by WST-8 assay | 2011 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 21, Issue:19
| Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative. |
| AID1105458 | Antifungal activity against Aspergillus fumigatus ATCC 40640 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID607601 | Cytotoxicity against human U373 cells assessed as growth inhibition at MTT assay-related IC50 by quantitative video microscopy relative to control | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID1359358 | Increase in TRP1 expression in mouse Melan-a cells at 40 uM after 72 hrs by Western blot analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1359344 | Increase in tyrosinase mRNA expression in mouse Melan-a cells at 40 uM after 24 hrs by SYBR green dye based qRT-PCR analysis | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID607594 | Cytotoxicity against human OE21 cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID356717 | Antiinflammatory activity against TPA-induced ear edema in mouse assessed inhibition of edema at 0.50 mg/ear | 2001 | Journal of natural products, Jul, Volume: 64, Issue:7
| Antiinflammatory constituents from Heterotheca inuloides. |
| AID140324 | Compound was tested for the inhibitory activity against mouse macrophage RAW 264.7 cells at the concentration of 50 uM; Inactive | 2000 | Bioorganic & medicinal chemistry letters, Jan-03, Volume: 10, Issue:1
| 1,1-Dimethylallylcoumarins potently suppress both lipopolysaccharide- and interferon-gamma-induced nitric oxide generation in mouse macrophage RAW 264.7 cells. |
| AID1359340 | Induction of melanogenesis in mouse Melan-a cells assessed as increase in melanin content at 40 uM after 72 hrs relative to control | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1359366 | Binding affinity to ERbeta in mouse Melan-a cells | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1105455 | Antifungal activity against Aspergillus flavus LM 210 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID637774 | Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assay | 2012 | Bioorganic & medicinal chemistry, Jan-15, Volume: 20, Issue:2
| Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor. |
| AID449579 | Anticonvulsant activity in mouse after 30 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID1359331 | Cytotoxicity against mouse Melan-a cells assessed as effect on cell viability at 40 uM after 24 to 72 hrs by trypan blue exclusion assay | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Natural oxyprenylated coumarins are modulators of melanogenesis. |
| AID1501441 | Drug metabolism assessed as dimer formation under sunlight exposed for 3 days by TLC method | 2017 | Journal of natural products, 09-22, Volume: 80, Issue:9
| Characterization of the Degradation Profile of Umbelliprenin, a Bioactive Prenylated Coumarin of a Ferulago Species. |
| AID607596 | Cytotoxicity against human PC3 cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID607595 | Cytotoxicity against human A549 cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID683122 | Inhibition of soybean 15-lipoxygenase by MBTH-DMAB method | 2012 | European journal of medicinal chemistry, Nov, Volume: 57 | Synthesis and SAR studies of mono O-prenylated coumarins as potent 15-lipoxygenase inhibitors. |
| AID1105459 | Antifungal activity against Aspergillus fumigatus ATCC 46913 after 72 hr by broth microdilution method | 2013 | International journal of molecular sciences, Jan-10, Volume: 14, Issue:1
| Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity. |
| AID637775 | Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate at 500 uM after 60 mins by fluorescence quenching assay | 2012 | Bioorganic & medicinal chemistry, Jan-15, Volume: 20, Issue:2
| Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor. |
| AID376062 | Antimutagenic activity in Salmonella Typhimurium TA102 assessed as protection against hydrogen peroxide-induced mutation at 1 ug/plate after 2 days by modified Ames test | 1999 | Journal of natural products, Oct, Volume: 62, Issue:10
| Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations. |
| AID449578 | Anticonvulsant activity in mouse after 15 mins by MES test | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18
| Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents. |
| AID607597 | Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |