aminoglutethimide has been researched along with Seizures in 5 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures." | 7.73 | Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005) |
| "The antiseizure effect of tested combinations was not sex-dependent and not reversed by hydrocortisone pretreatment." | 5.33 | Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005) |
| " The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures." | 3.73 | Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005) |
| "The antiseizure effect of tested combinations was not sex-dependent and not reversed by hydrocortisone pretreatment." | 1.33 | Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005) |
| "Doses of kainic acid producing convulsions and death were not affected by stress, but they were enhanced by aminoglutethimide." | 1.31 | Anticonvulsive effect of swim stress in mice. ( Jazvinsćak, M; Mirković, K; Pericić, D; Svob, D, 2000) |
| "glucocorticoids on convulsions." | 1.29 | Type I corticosteroid receptors modulate PTZ-induced convulsions of withdrawal seizure prone mice. ( Crabbe, JC; Keith, LD; Roberts, AJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borowicz, KK | 2 |
| Czuczwar, SJ | 2 |
| Roberts, AJ | 1 |
| Crabbe, JC | 1 |
| Keith, LD | 1 |
| Pericić, D | 1 |
| Svob, D | 1 |
| Jazvinsćak, M | 1 |
| Mirković, K | 1 |
| Maxson, SC | 1 |
| Sze, PY | 1 |
5 other studies available for aminoglutethimide and Seizures
| Article | Year |
|---|---|
Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats.
Topics: Adrenergic Agents; Aminoglutethimide; Amygdala; Animals; Anticonvulsants; Clonazepam; Disease Models | 2005 |
Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats.
Topics: Aminoglutethimide; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Dru | 2005 |
Type I corticosteroid receptors modulate PTZ-induced convulsions of withdrawal seizure prone mice.
Topics: Aminoglutethimide; Animals; Desoxycorticosterone; Dexamethasone; Disease Susceptibility; Ethanol; Ma | 1993 |
Anticonvulsive effect of swim stress in mice.
Topics: 5-alpha Reductase Inhibitors; Aminoglutethimide; Animals; Bridged Bicyclo Compounds, Heterocyclic; C | 2000 |
Glucocorticoids and development of audiogenic seizure susceptibility in DBA/1Bg mice.
Topics: Acoustic Stimulation; Aminoglutethimide; Animals; Genes; Glucocorticoids; Mice; Mice, Inbred C57BL; | 1977 |