cyclocreatine has been researched along with Seizures in 3 studies
cyclocreatine: structure given in first source
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Creatine Transporter Deficiency (CTD) is an inborn error of metabolism presenting with intellectual disability, behavioral disturbances and epilepsy." | 3.96 | Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency. ( Alessandrì, MG; Baroncelli, L; Battini, R; Butt, M; Cacciante, F; Cerri, E; Cioni, G; Do, MT; Gennaro, M; Lupori, L; Mazziotti, R; McKew, JC; Pizzorusso, T; Putignano, E; Sagona, G, 2020) |
| "Rats in experiment 1 received 1% creatine or cyclocreatine chow from age (P) 21-65 days, underwent kainate induced status epilepticus on P35 and were compared, as adults, to kainate alone rats and to normal controls." | 3.72 | Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats. ( Abu Rialy, S; Farhat, F; Francis, E; Geha, G; Kurdit, RM; Lteif, L; Maraashli, W; Mikati, MA; Rahmeh, AA, 2004) |
| " Exposure at the no observed adverse effect level in creatine transporter-deficient (554 μg*hr/ml) mice exceeded exposure at the maximum tolerated dose in wild-type (248 μg*hr/ml) mice." | 1.62 | Use of an animal model of disease for toxicology enables identification of a juvenile no observed adverse effect level for cyclocreatine in creatine transporter deficiency. ( Butt, M; Cavagnaro, J; Do, MT; McKew, JC; Terse, PS, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cacciante, F | 1 |
| Gennaro, M | 1 |
| Sagona, G | 1 |
| Mazziotti, R | 1 |
| Lupori, L | 1 |
| Cerri, E | 1 |
| Putignano, E | 1 |
| Butt, M | 2 |
| Do, MT | 2 |
| McKew, JC | 2 |
| Alessandrì, MG | 1 |
| Battini, R | 1 |
| Cioni, G | 1 |
| Pizzorusso, T | 1 |
| Baroncelli, L | 1 |
| Cavagnaro, J | 1 |
| Terse, PS | 1 |
| Mikati, MA | 1 |
| Kurdit, RM | 1 |
| Rahmeh, AA | 1 |
| Farhat, F | 1 |
| Abu Rialy, S | 1 |
| Lteif, L | 1 |
| Francis, E | 1 |
| Geha, G | 1 |
| Maraashli, W | 1 |
3 other studies available for cyclocreatine and Seizures
| Article | Year |
|---|---|
Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency.
Topics: Animals; Autistic Disorder; Blood-Brain Barrier; Brain Diseases, Metabolic, Inborn; Cerebrovascular | 2020 |
Use of an animal model of disease for toxicology enables identification of a juvenile no observed adverse effect level for cyclocreatine in creatine transporter deficiency.
Topics: Animals; Antineoplastic Agents; Brain; Brain Diseases, Metabolic, Inborn; Creatine; Creatinine; Dise | 2021 |
Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats.
Topics: Acute Disease; Aggression; Animals; Anticonvulsants; Creatine; Creatinine; Dietary Supplements; Emot | 2004 |