fomepizole has been researched along with Seizures in 2 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of a common industrial solvent, trichloroethylene (TCE), which was once used as an anesthetic agent but its in vivo mechanism is still unknown, on convulsant-induced seizures in mice were examined." | 3.71 | Acute exposure to trichloroethylene differentially alters the susceptibility to chemoconvulsants in mice. ( Chen, HH; Chiu, TH; Shih, CL, 2001) |
| "The case of a 43-year-old man who ingested 30 mL of a homemade 1,4-butanediol solution and who developed general seizures and coma has been reported here." | 3.71 | Treatment of a 1,4-butanediol poisoning with fomepizole. ( Baud, FJ; Fompeydie, D; Garnier, R; Mégarbane, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shih, CL | 1 |
| Chen, HH | 1 |
| Chiu, TH | 1 |
| Mégarbane, B | 1 |
| Fompeydie, D | 1 |
| Garnier, R | 1 |
| Baud, FJ | 1 |
2 other studies available for fomepizole and Seizures
| Article | Year |
|---|---|
Acute exposure to trichloroethylene differentially alters the susceptibility to chemoconvulsants in mice.
Topics: Animals; Anticonvulsants; Antidotes; Convulsants; Disulfiram; Dose-Response Relationship, Drug; Drug | 2001 |
Treatment of a 1,4-butanediol poisoning with fomepizole.
Topics: Adult; Antidotes; Butylene Glycols; Coma; Fomepizole; Humans; Hydroxybutyrates; Infusions, Intraveno | 2002 |