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1-(2-trifluoromethylphenyl)imidazole and Seizures

1-(2-trifluoromethylphenyl)imidazole has been researched along with Seizures in 2 studies

1-(2-trifluoromethylphenyl)imidazole: an inhibitor of neuronal nitric oxide synthase in mouse

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"nNOS(-/-) mice exhibited severe convulsions following injection with a subconvulsive dose of PTZ (40 mg/kg i."1.35Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase. ( Itoh, K; Watanabe, M, 2009)
"7-NI prevents convulsions, including 2-amino-4-methylphosphinobutyric acid (glufosinate)-induced convulsions, in experimental models."1.35Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition. ( Kikuchi-Utsumi, K; Matsumura, N; Nakaki, T, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Itoh, K1
Watanabe, M1
Matsumura, N1
Kikuchi-Utsumi, K1
Nakaki, T1

Other Studies

2 other studies available for 1-(2-trifluoromethylphenyl)imidazole and Seizures

ArticleYear
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase.
    Neuroscience, 2009, Mar-17, Volume: 159, Issue:2

    Topics: Animals; Convulsants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug;

2009
Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Aminobutyrates; Animals; Anticonvulsants; Brain; Herbicides; Imidazoles; Indazoles; Male; Mice; Mice

2008