1-(4-bromobenzoyl)piperazine-2,3-dicarboxylic acid profile

1-(4-bromobenzoyl)piperazine-2,3-dicarboxylic acid is a complex organic molecule with a specific structure. Unfortunately, it's not a widely recognized or documented compound. There's limited information available about its properties, uses, or significance in research.

Here's why it's difficult to find information:

* **Specificity:** The compound's name is highly specific. It refers to a particular chemical structure and a specific arrangement of atoms. Unless it has been extensively studied and published, finding information about it might be challenging.
* **Lack of commercial availability:** If the compound is not commercially available, it suggests that it might not be a widely used or studied compound.
* **Limited research interest:** If there's little interest in the compound for research, it's unlikely to have a significant amount of published research.

**Possible reasons for the lack of information:**

* **Novel compound:** It could be a newly synthesized compound that hasn't been fully characterized or investigated yet.
* **Intermediate compound:** It could be an intermediate compound used in the synthesis of a larger or more complex molecule.
* **Specific application:** Its research significance might be limited to a specific niche area or application that isn't widely known.

**How to find more information:**

* **Check chemical databases:** You can search online chemical databases like PubChem, ChemSpider, or Reaxys. These databases might have some information about the compound, including its structure and potential properties.
* **Contact research groups:** Reach out to researchers in related fields, particularly those working with piperazine-based compounds or compounds with a similar structure.
* **Consult scientific literature:** Search scientific journals and databases like PubMed or Scopus using keywords related to the compound's structure or potential applications.

It's important to remember that the lack of readily available information doesn't necessarily mean the compound is unimportant. It might simply be a less-studied compound or have a specific niche application.

1-(4-bromobenzoyl)piperazine-2,3-dicarboxylic acid: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	124528
SCHEMBL ID	6348156
MeSH ID	M0133203

Synonym
1-bbpd
1-(4-bromobenzoyl)piperazine-2,3-dicarboxylic acid
94856-92-5
2,3-piperazinedicarboxylic acid, 1-(4-bromobenzoyl)-
pbb-pzda
SCHEMBL6348156
4-(4-bromobenzoyl)-piperazine-2,3-dicarboxylic acid
WDVICMJSSBICSA-UHFFFAOYSA-N
DTXSID00915241
1-(p-bromobenzoyl)-piperazine-2,3-dicarboxylic acid
PD075858

Excerpt	Relevance	Reference
" Kynurenate and the piperazine derivatives blocked up to 80% of the synaptic response at doses of 1000 microM, with single-affinity dose-response curves."	( Antagonism of lateral olfactory tract synaptic potentials in rat prepyriform cortex slices. Cotman, CW; Ganong, AH; Hearn, TJ, 1986)	0.27

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (80.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
2-amino-4-phosphonobutyric acid 2-amino-4-phosphonobutyric acid: glutamate antagonist in locust muscle; structure; do not confuse with L-AP4, which is the propionic acid version	1.96	1
2-amino-6-phosphonohexanoic acid 2-amino-6-phosphonohexanoic acid: RN given refers to DL-isomer	1.97	1
kynurenic acid Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.. kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.	1.96	1	monohydroxyquinoline; quinolinemonocarboxylic acid	G-protein-coupled receptor agonist; human metabolite; neuroprotective agent; nicotinic antagonist; NMDA receptor antagonist; Saccharomyces cerevisiae metabolite
aspartic acid Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.. aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent. L-aspartic acid : The L-enantiomer of aspartic acid.	2.37	2	aspartate family amino acid; aspartic acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; mouse metabolite; neurotransmitter
glutamine Glutamine: A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.. L-glutamine : An optically active form of glutamine having L-configuration.. glutamine : An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.	2.37	2	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
kainic acid Kainic Acid: (2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.	2.66	3	dicarboxylic acid; L-proline derivative; non-proteinogenic L-alpha-amino acid; pyrrolidinecarboxylic acid	antinematodal drug; excitatory amino acid agonist
norleucine Norleucine: An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it does not contain SULFUR.. L-norleucine : A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.	1.97	1	2-aminohexanoic acid; L-alpha-amino acid zwitterion; non-proteinogenic L-alpha-amino acid
n-methylaspartate N-Methylaspartate: An amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors (RECEPTORS, NMDA).. N-methyl-D-aspartic acid : An aspartic acid derivative having an N-methyl substituent and D-configuration.	2.37	2	amino dicarboxylic acid; D-alpha-amino acid; D-aspartic acid derivative; secondary amino compound	neurotransmitter agent
quisqualic acid Quisqualic Acid: An agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis.	2.37	2	non-proteinogenic alpha-amino acid
gamma-glutamylaminomethylsulfonic acid [no description available]	2.37	2
1-(4-chlorobenzoyl)piperazine-2,3-dicarboxylic acid 1-(4-chlorobenzoyl)piperazine-2,3-dicarboxylic acid: structure given in first source	2.37	2
oxadiazoles Oxadiazoles: Compounds containing five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom which exist in various regioisomeric forms.	2.37	2

Condition	Indicated	Relationship Strength	Studies	Trials
Absence Seizure [description not available]	0	1.96	1	0
Seizures Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.	0	1.96	1	0

1-(4-bromobenzoyl)piperazine-2,3-dicarboxylic acid

Description

Cross-References

Synonyms (11)

Research Excerpts

Dosage Studied

Research

Studies (5)

Market Indicators

Research Demand Index: 12.51

Study Types