Page last updated: 2024-11-06

3-chloropropionamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-Chloropropionamide, also known as β-chloropropionamide, is an organic compound with the formula ClCH2CH2CONH2. It is a colorless solid. 3-chloropropionamide is a versatile synthetic intermediate used in the production of various chemicals and pharmaceuticals. It is also a potential building block for polymers and other functional materials. Research on 3-chloropropionamide primarily focuses on its synthesis, reactivity, and applications. Its biological activity, particularly as a potential antimicrobial or herbicide agent, is also being explored. Studies on 3-chloropropionamide are motivated by its potential as a valuable chemical intermediate and the need to understand its environmental impact and potential biological effects.'

3-chloropropionamide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID79982
CHEMBL ID171266
SCHEMBL ID120934
SCHEMBL ID10439099
MeSH IDM0403467

Synonyms (34)

Synonym
ai3-21062
unii-1a4dt52kjv
einecs 227-542-2
1a4dt52kjv ,
nsc 401789
3-chloropropionamide
5875-24-1
propanamide, 3-chloro-
nsc-401789
nsc401789
3-chloropropionamide, 98%
AKOS000141502
3-chloropropanamide
3-chloro-propionamide
CHEMBL171266 ,
jqdxzjyausvhdh-uhfffaoysa-
inchi=1/c3h6clno/c4-2-1-3(5)6/h1-2h2,(h2,5,6)
EN300-53733
BBL011453
STL146565
FT-0635892
S12033
SCHEMBL120934
3-chloro-propanamide
SCHEMBL10439099
3-chloropropanamide #
mfcd00008040
AS-54557
CS-0204808
bdbm50224816
DTXSID70974269
3-chloropropanimidic acid
.beta.-chloropropionamide
SY101532
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (2)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Alcohol dehydrogenase E chainEquus caballus (horse)Ki5,300.00000.14122.89278.7000AID33720
Alcohol dehydrogenase S chainEquus caballus (horse)Ki5,300.00000.14122.89278.7000AID33720
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID183376In vivo inhibition of ethanol metabolism following 1 mMol/Kg p.o.1983Journal of medicinal chemistry, Jun, Volume: 26, Issue:6
Inhibition by carboxamides and sulfoxides of liver alcohol dehydrogenase and ethanol metabolism.
AID33720In vitro inhibition against horse liver alcohol dehydrogenase1983Journal of medicinal chemistry, Jun, Volume: 26, Issue:6
Inhibition by carboxamides and sulfoxides of liver alcohol dehydrogenase and ethanol metabolism.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-199012 (92.31)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.50 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]