progabide has been researched along with Seizures in 35 studies
*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (68.57) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 4 (11.43) | 29.6817 |
| 2010's | 2 (5.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, JK; Wall, GM | 1 |
| Jiang, Z; Park, E; Qu, A; Song, PX | 1 |
| Sumi, M; Tango, T | 1 |
| Westgate, PM | 1 |
| Lin, X; Wang, YG; Zhu, M | 1 |
| Bartholini, G | 1 |
| Bryere, P; Kaijima, M; Naquet, R; Valin, A | 1 |
| Bovier, P; Broekkamp, CL; Lloyd, KG; Worms, P | 1 |
| Bartholini, G; Lloyd, KG; Scatton, B; Worms, P; Zivkovic, B | 1 |
| Bossi, L; Lloyd, KG; Morselli, PL; Munari, C; Worms, P | 1 |
| Fariello, RG; Golden, GT | 1 |
| Albertson, TE; Joy, RM; Stark, LG | 1 |
| Georgiev, VP; Kambourova, TS; Lazarova, MB | 1 |
| Hougaard, P; Lee, ML; Whitmore, GA | 1 |
| Kozuchová, A; Mares, P; Stanková, L | 1 |
| Gadbury, GL; Iyer, HK | 1 |
| Cook, RJ; Wei, W | 1 |
| Gautam, SK; Kulkarni, SK | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC | 1 |
| Lloyd, KG; Perrault, G; Zivkovic, B | 1 |
| Rastogi, SK; Ticku, MK | 2 |
| Fadda, F; Gessa, GL; Meloni, R; Mosca, E | 1 |
| Löscher, W; Schwark, WS | 1 |
| Chweh, AY; Swinyard, EA; Ulloque, RA | 1 |
| Chweh, AY; Lin-Michell, E; Swinyard, EA | 1 |
| Little, HJ; Nutt, DJ; Taylor, SC | 1 |
| Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B | 1 |
| de Feo, MR; Mecarelli, O; Ricci, GF; Rina, MF | 1 |
| Bowman, T; Cloyd, J; Crosby, C; Dreifuss, FE; Graves, N; Jacobs, M; Leppik, IE; Porter, R; Santilli, N; Stackman, J | 1 |
| Fariello, R; Maddrey, WC; Munoz, SJ | 1 |
| Brundage, RC; Cloyd, JC; Graves, NM; Leppik, IE; Welty, TE | 1 |
| Chweh, AY; Swinyard, EA; Wolf, HH | 1 |
| Löscher, W | 1 |
1 review(s) available for progabide and Seizures
| Article | Year |
|---|---|
[Implications of GABAergic synapses in neuropsychiatry].
Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Anxiety; Brain; Cats; Cerebral Cortex; Depressive Disorder; Disease Models, Animal; Dyskinesia, Drug-Induced; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Haplorhini; Humans; Mental Disorders; Muscimol; Receptors, GABA-A; Seizures; Synapses; Synaptic Transmission | 1985 |
2 trial(s) available for progabide and Seizures
| Article | Year |
|---|---|
A controlled study of progabide in partial seizures: methodology and results.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Seizures | 1987 |
Effect of progabide on serum phenytoin and carbamazepine concentrations.
Topics: Adult; Carbamazepine; Convulsants; Double-Blind Method; Drug Evaluation; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Random Allocation; Seizures | 1987 |
32 other study(ies) available for progabide and Seizures
| Article | Year |
|---|---|
Metabolism of 3-(p-chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype gamma-aminobutyric acid prodrug to lactam and gamma-aminobutyric acid type metabolites.
Topics: Amino Acids; Animals; Baclofen; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Isoniazid; Lactams; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Molecular Structure; Monoamine Oxidase; Oxidation-Reduction; Prodrugs; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1989 |
Quadratic inference functions in marginal models for longitudinal data.
Topics: Anticonvulsants; Computer Simulation; Data Interpretation, Statistical; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Models, Statistical; Seizures; Software | 2009 |
Inference on the rate ratio of recurrent events for the matched pairs design.
Topics: Anticonvulsants; Data Interpretation, Statistical; Epilepsy; gamma-Aminobutyric Acid; Humans; Incidence; Product Surveillance, Postmarketing; Randomized Controlled Trials as Topic; Recurrence; Sample Size; Seizures | 2010 |
A bias correction for covariance estimators to improve inference with generalized estimating equations that use an unstructured correlation matrix.
Topics: Anticonvulsants; Bias; Computer Simulation; Epilepsy; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Models, Statistical; Seizures | 2013 |
Robust estimating functions and bias correction for longitudinal data analysis.
Topics: Age Factors; Anticonvulsants; Bias; Data Interpretation, Statistical; Epilepsy; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Randomized Controlled Trials as Topic; Seizures | 2005 |
Pharmacology of the GABAergic system: effects of progabide, a GABA receptor agonist.
Topics: Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Humans; Norepinephrine; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Serotonin; Synaptic Transmission | 1984 |
Differential effects of the benzodiazepine antagonist Ro 15-1788 on two types of myoclonus in baboon Papio papio.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepinones; Flumazenil; gamma-Aminobutyric Acid; Light; Lorazepam; Myoclonus; Papio; Seizures | 1983 |
Reversal of the antiaversive and anticonvulsant actions of diazepam, but not of progabide, by a selective antagonist of benzodiazepine receptors.
Topics: Animals; Anxiety; Benzodiazepinones; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Humans; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures | 1981 |
Pharmacological and therapeutic actions of GABA receptor agonists.
Topics: Bipolar Disorder; Emotions; gamma-Aminobutyric Acid; Humans; Movement Disorders; Norepinephrine; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Serotonin | 1983 |
Indications for the use of gamma-aminobutyric acid (GABA)-agonists in convulsant disorders.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsies, Partial; Epilepsy; gamma-Aminobutyric Acid; Humans; Nervous System; Papio; Seizures; Synapses | 1983 |
Penicillin spikes in rats. Limitations of a simple model for the study of anticonvulsants.
Topics: Action Potentials; Animals; Anticonvulsants; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Penicillins; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Taurine; Time Factors | 1984 |
An analysis of the actions of progabide, a specific GABA receptor agonist, on kindling and kindled seizures.
Topics: Amygdala; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Seizures | 1984 |
Further evidence for the interactions between angiotensin II and GABAergic transmission in pentylenetetrazol kindling seizures in mice.
Topics: Angiotensin II; Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Phenylurea Compounds; Receptors, GABA; Seizures | 1995 |
Analysis of overdispersed count data by mixtures of Poisson variables and Poisson processes.
Topics: Anticonvulsants; Biometry; Epilepsy; gamma-Aminobutyric Acid; Humans; Likelihood Functions; Normal Distribution; Poisson Distribution; Probability; Seizures; Statistical Distributions | 1997 |
Anticonvulsant effect of progabide in rats during ontogenesis.
Topics: Aging; Animals; Anticonvulsants; Behavior, Animal; Convulsants; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1997 |
Unit-treatment interaction and its practical consequences.
Topics: Analysis of Variance; Anticonvulsants; Clinical Trials as Topic; Epilepsy; gamma-Aminobutyric Acid; Humans; Likelihood Functions; Models, Statistical; Randomized Controlled Trials as Topic; Seizures | 2000 |
Selection effects in randomized trials with count data.
Topics: Anticonvulsants; Computer Simulation; Electrocardiography, Ambulatory; Epilepsy; gamma-Aminobutyric Acid; Humans; Models, Biological; Myocardial Ischemia; Randomized Controlled Trials as Topic; Seizures; Selection Bias | 2002 |
GABA/BZ-and NMDA-receptor interaction in digoxin-induced convulsions in rats.
Topics: Animals; Baclofen; Diazepam; Digoxin; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Salts; Seizures | 1991 |
Are GABAB receptors involved in the pharmacological effects of ethanol?
Topics: Animals; Baclofen; Cells, Cultured; Chlorine; Diazepam; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Picrotoxin; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Spinal Cord | 1990 |
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1988 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
Suppression by progabide of ethanol withdrawal syndrome in rats.
Topics: Acoustic Stimulation; Animals; Ethanol; gamma-Aminobutyric Acid; Humans; Male; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission; Tremor | 1985 |
Evaluation of different GABA receptor agonists in the kindled amygdala seizure model in rats.
Topics: Amygdala; Animals; Female; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Isoxazoles; Kindling, Neurologic; Muscimol; Muscle Relaxation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1985 |
Effects of gamma-aminobutyric acid (GABA) receptor agonists on the neurotoxicity and anticonvulsant activity of barbiturates in mice.
Topics: Animals; Anticonvulsants; Baclofen; Barbiturates; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Nervous System; Oxazoles; Receptors, GABA-A; Seizures | 1986 |
Effect of ethosuximide alone and in combination with gamma-aminobutyric acid receptor agonists on brain gamma-aminobutyric acid concentration, anticonvulsant activity and neurotoxicity in mice.
Topics: Animals; Brain Chemistry; Ethosuximide; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Mice, Inbred Strains; Nervous System; Pentylenetetrazole; Receptors, GABA-A; Seizures | 1986 |
Anticonvulsant profile of drugs which facilitate GABAergic transmission on convulsions mediated by a GABAergic mechanism.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; gamma-Aminobutyric Acid; Male; Pentobarbital; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1986 |
The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.
Topics: Animals; Bicuculline; Body Temperature; Carbolines; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1986 |
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Clomipramine; Depressive Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Olfactory Bulb; Rats; Receptors, GABA-A; Seizures; Sleep | 1987 |
Effects of progabide on bicuculline-induced epileptic seizures in developing rats.
Topics: Aging; Animals; Anticonvulsants; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Seizures; Status Epilepticus | 1988 |
Submassive hepatic necrosis associated with the use of progabide: a GABA receptor agonist.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Female; gamma-Aminobutyric Acid; Humans; Liver; Liver Function Tests; Necrosis; Seizures | 1988 |
Involvement of a GABAergic mechanism in the pharmacologic action of phenytoin.
Topics: Animals; Anticonvulsants; Baclofen; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Phenytoin; Postural Balance; Seizures | 1986 |
Anticonvulsant action of GABA agonists and prodrugs on minor and major seizures in epileptic gerbils. Comparison with mouse models of seizure states.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Female; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Isoxazoles; Mice; Pentylenetetrazole; Seizures; Species Specificity | 1985 |