oxamniquine has been researched along with Seizures in 4 studies
Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)
oxamniquine : A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol : A member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three patients who were treated for schistosomiasis mansoni with oxamniquine suffered generalized seizures." | 7.67 | Seizures associated with oxamniquine therapy. ( Bauer, AG; Malcolm, AD; Overbosch, D; Stokvis, H; Stuiver, PC, 1986) |
| "A Tanzanian man with a known seizure disorder was admitted to hospital for treatment of schistosomiasis mansoni." | 5.26 | Seizures and electroencephalograph changes associated with oxamniquine therapy. ( Keystone, JS, 1978) |
| "Three patients who were treated for schistosomiasis mansoni with oxamniquine suffered generalized seizures." | 3.67 | Seizures associated with oxamniquine therapy. ( Bauer, AG; Malcolm, AD; Overbosch, D; Stokvis, H; Stuiver, PC, 1986) |
| "Oxamniquine is a potent schistosomicide used clinically in the treatment of infections due to Schistosoma mansoni." | 1.29 | Preliminary investigations of some derivatives of oxamniquine. ( Karekezi, CW; Lucas, PD; Marples, BA; Salt, WG, 1995) |
| "A Tanzanian man with a known seizure disorder was admitted to hospital for treatment of schistosomiasis mansoni." | 1.26 | Seizures and electroencephalograph changes associated with oxamniquine therapy. ( Keystone, JS, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karekezi, CW | 1 |
| Lucas, PD | 1 |
| Marples, BA | 1 |
| Salt, WG | 1 |
| Keystone, JS | 1 |
| Stokvis, H | 2 |
| Bauer, AG | 2 |
| Stuiver, PC | 2 |
| Malcolm, AD | 2 |
| Overbosch, D | 2 |
4 other studies available for oxamniquine and Seizures
| Article | Year |
|---|---|
Preliminary investigations of some derivatives of oxamniquine.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Oxam | 1995 |
Seizures and electroencephalograph changes associated with oxamniquine therapy.
Topics: Adolescent; Adult; Electroencephalography; Female; Humans; Male; Nitroquinolines; Oxamniquine; Seizu | 1978 |
Seizures associated with oxamniquine therapy.
Topics: Adult; Electroencephalography; Humans; Male; Nitroquinolines; Oxamniquine; Schistosomiasis mansoni; | 1986 |
Convulsions after oxamniquine.
Topics: Ethnicity; Humans; Nitroquinolines; Oxamniquine; Seizures | 1987 |