Page last updated: 2024-11-04

fluoroacetic acid and Seizures

fluoroacetic acid has been researched along with Seizures in 7 studies

fluoroacetic acid: N1 same as NM; RN given refers to parent cpd
fluoroacetic acid : A haloacetic acid that is acetic acid in which one of the methyl hydrogens is substituted by fluorine.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
" Neurotoxic signs such as hyperesthesia and/or excitement, as well as convulsions, were observed in both FBAL x HCl and FA x Na groups; these toxic signs were also found in the UFT group."1.32Neurotoxic effects of alpha-fluoro-beta-alanine (FBAL) and fluoroacetic acid (FA) on dogs. ( Ariyoshi, T; Yada, H; Yamashita, K, 2004)
" The dose-response curves constructed for the convulsant effects of PM and MFA were parallel and the CD50s were 630 mg/kg (508-781) and 0."1.28Is monofluoracetic acid the active neurotoxic principle in Palicourea marcgravii (St. Hill) leaves? ( Brizolla, M; Eckschmidt, M; Palermo-Neto, J; Tarragá, DP, 1989)
" Plasma and tissue SMFA concentrations were generally lower than the corresponding stomach fluid SMFA concentrations for all dosage groups."1.26Inorganic and organic fluoride concentrations in tissues after the oral administration of sodium monofluoroacetate (Compound 1080) to rats. ( Egekeze, JO; Oehme, FW, 1979)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Liu, L1
Li, F1
Dong, Z1
Dong, G1
Xu, J1
Liu, W1
Wang, X1
Hai, X1
Yu, K1
WARD, AA1
Yamashita, K1
Yada, H1
Ariyoshi, T1
Marrazzi, MA1
Holliday, JF1
Gorniak, SL1
Palermo-Neto, J2
Spinosa, HS1
Egekeze, JO1
Oehme, FW1
Eckschmidt, M1
Brizolla, M1
Tarragá, DP1

Other Studies

7 other studies available for fluoroacetic acid and Seizures

ArticleYear
Plasma fluoroacetic acid concentrations: Symptoms, hematological, and biochemical characteristics in patients with fluoroacetic acid poisoning in the emergency department.
    Human & experimental toxicology, 2020, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Creatine Kinase, MB Form; Emergency Servi

2020
Convulsive activity induced by fluoroacetate.
    Journal of neurophysiology, 1947, Volume: 10, Issue:2

    Topics: Fluoroacetates; Seizures

1947
Neurotoxic effects of alpha-fluoro-beta-alanine (FBAL) and fluoroacetic acid (FA) on dogs.
    The Journal of toxicological sciences, 2004, Volume: 29, Issue:2

    Topics: Administration, Oral; Animals; beta-Alanine; Dogs; Fluoroacetates; Fluorouracil; Hyperesthesia; Male

2004
Comparison of insulin hypoglycemia-induced and fluoroacetate-induced convulsions in gold thioglucose lesioned mice.
    Biochemical pharmacology, 1981, Dec-01, Volume: 30, Issue:23

    Topics: Animals; Aurothioglucose; Blood Glucose; Body Weight; Citrates; Citric Acid; Female; Fluoroacetates;

1981
Effects of acetamide on experimentally-induced Palicourea marcgravii (St Hill) poisoning in rats.
    Veterinary and human toxicology, 1994, Volume: 36, Issue:2

    Topics: Acetamides; Animals; Antidotes; Fluoroacetates; Male; Plant Poisoning; Rats; Rats, Wistar; Seizures

1994
Inorganic and organic fluoride concentrations in tissues after the oral administration of sodium monofluoroacetate (Compound 1080) to rats.
    Toxicology, 1979, Volume: 15, Issue:1

    Topics: Animals; Fluoride Poisoning; Fluorides; Fluoroacetates; Gastric Juice; Kidney; Lethal Dose 50; Liver

1979
Is monofluoracetic acid the active neurotoxic principle in Palicourea marcgravii (St. Hill) leaves?
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1989, Volume: 22, Issue:8

    Topics: Animals; Female; Fluoroacetates; Lethal Dose 50; Plant Extracts; Rats; Rats, Inbred Strains; Seizure

1989
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