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dehydroepiandrosterone and Seizures

dehydroepiandrosterone has been researched along with Seizures in 6 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Dehydroepiandrosterone (DHEA), a neuroactive androgen steroid, has antiepileptic action in iron-induced experimental epilepsy (which models post-traumatic clinical epilepsy)."3.79Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters. ( Mishra, M; Mukherjee, S; Sharma, D; Singh, R, 2013)
" The anesthesia induced by 1-amino-5-bromouracil was potentiated by diazepam, pentobarbital, and muscimol, and was antagonized by picrotoxin but not by bicuculline."3.69Effects of 1-amino-5-bromouracil on the benzodiazepine-GABAA receptor complex. ( Imaizumi, M; Machida, H; Miyazaki, S, 1994)
"A generalized seizure, associated with concurrent intake of DHEA."1.35Onset of late posttraumatic seizure after dehydroepiandrosterone treatment. ( Bentov, Y; Ifergane, G; Karp, G; Masalha, R, 2009)
"Other childhood seizures are also responsive to ACTH."1.31The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats. ( Burnham, WM; Edwards, HE; Vimal, S, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mishra, M1
Singh, R1
Mukherjee, S1
Sharma, D1
Karp, G1
Bentov, Y1
Masalha, R1
Ifergane, G1
Wiener, P1
HEUSER, G1
LING, GM1
BUCHWALD, NA1
Miyazaki, S1
Imaizumi, M1
Machida, H1
Edwards, HE1
Vimal, S1
Burnham, WM1

Reviews

1 review available for dehydroepiandrosterone and Seizures

ArticleYear
Neuroactive steroids, relaxation, and seizure control.
    The International journal of neuroscience, 2003, Volume: 113, Issue:5

    Topics: Anxiety; Chloride Channels; Dehydroepiandrosterone; Glutamic Acid; Humans; Hypothalamo-Hypophyseal S

2003

Other Studies

5 other studies available for dehydroepiandrosterone and Seizures

ArticleYear
Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters.
    Epilepsy research, 2013, Volume: 106, Issue:1-2

    Topics: Amino Acid Transport System X-AG; Animals; Anticonvulsants; Chlorides; Dehydroepiandrosterone; Elect

2013
Onset of late posttraumatic seizure after dehydroepiandrosterone treatment.
    Fertility and sterility, 2009, Volume: 91, Issue:3

    Topics: Adult; Craniocerebral Trauma; Dehydroepiandrosterone; Dietary Supplements; Female; Fertility Agents,

2009
SEDATION OR SEIZURES AS DOSE-DEPENDENT EFFECTS OF STEROIDS.
    Archives of neurology, 1965, Volume: 13

    Topics: 17-Hydroxycorticosteroids; Animals; Behavior, Animal; Central Nervous System; Dehydroepiandrosterone

1965
Effects of 1-amino-5-bromouracil on the benzodiazepine-GABAA receptor complex.
    European journal of pharmacology, 1994, Dec-12, Volume: 271, Issue:1

    Topics: Anesthesia; Animals; Anti-Anxiety Agents; Anticonvulsants; Bridged Bicyclo Compounds; Bridged Bicycl

1994
The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats.
    Experimental neurology, 2002, Volume: 175, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Dehydroepiandrosterone; Desoxycor

2002