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hexobarbital and Seizures

hexobarbital has been researched along with Seizures in 68 studies

Hexobarbital: A barbiturate that is effective as a hypnotic and sedative.
hexobarbital : A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
" Administration of both the extract and diazepam (2 mg/kg) reduced spontaneous locomotory activity, potentiated hexobarbital (60 mg/kg)-induced sleeping parameters and prevented pentylenetetrazole (80 mg/kg)-induced seizures relative to the controls."3.78Effects of Hypericum montbretti extract on the central nervous system and involvement of GABA (A)/Benzodiazepine receptors in its pharmacological activity. ( Can, OD; Ozkay, UD, 2012)
"01) dose dependent increase in onset of convulsion compared to the control for strychnine- and picrotoxin-induced seizures."3.76Anticonvulsant, anxiolytic and sedative activities of the aqueous root extract of Securidaca longepedunculata Fresen. ( Adeyemi, OO; Aigbe, FR; Akindele, AJ; Fagbo, FI; Yemitan, OK, 2010)
"Zoxazolamine paralysis, hexobarbital anesthesia and digitoxin convulsions were diminished in rats by 3 days of pretreatment with pregnenolone-16alpha-carbonitrile (PCN)."3.65Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine. ( Garg, BD; Kourounakis, P; Kovacs, K; Szabo, S; Tuchweber, B, 1977)
" Tremorine-induced tremor in mice was inhibited by NSP, while perphenazine-induced catalepsy in rats was not."3.65[Central activity, antihypertensive action and antiulcerogenic effects of neurotropin]. ( Hata, T; Kita, T; Yoneda, R, 1976)
"On day 3 a convulsion was induced by electricity in half of the rats (controls and barbital-treated) and 1 h later the sensitivity to hexobarbital was determined with a threshold test."1.27Interaction between spontaneous and electrically induced convulsions and their short- and long-term effects in the abstinence after chronic barbital treatment in the rat. ( Wahlström, G, 1983)
"Both compounds antagonized MES-induced seizures after administration to mice; oral ED50 values for 3 and 4 were 3."1.27Discovery and anticonvulsant activity of the potent metabolic inhibitor 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethylbenzamide. ( Beedle, EE; Clark, CR; Lawson, R; Leander, JD; Parli, CJ; Potts, BD; Robertson, DW, 1987)
"The barbital treatment induced a clear tolerance to the hexobarbital, which still could be detected on day 28 of abstinence."1.26The effects of atropine on the tolerance and the convulsions seen after withdrawal from forced barbital drinking in the rat. ( Wahlström, G, 1978)
"They did not antagonize electrogenic convulsions, amphetamine potentiated motility and the action of reserpine, and had no analgetic action."1.26Central action of new derivatives of tetrahydropirimidinedione-4,6. ( Barczyńska, J; Felsztyńska, J; Kedzierska, L; Wilimowski, M; Witkowska, M; Wojewódzki, W, 1979)
"The effect of electrically induced convulsions was tested on the tolerance to hexobarbital after chronic barbital treatment in male rats."1.26The interaction between electrically induced convulsions and tolerance in the abstinence period after chronic barbital treatments in the rat. ( Wahlström, G, 1976)
"Hexobarbital was infused continously."1.26The interaction between pilocarpine and hexobarbital in male rats. ( Wahlström, G, 1976)
"However, the effects of reserpine on convulsions due to leptazol and in causing ptosis were not antagonized by methyldopa."1.24INFLUENCE OF METHYLDOPA ON CENTRAL EFFECTS OF RESERPINE. ( BENFEY, BG; VARMA, DR, 1964)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199061 (89.71)18.7374
1990's3 (4.41)18.2507
2000's2 (2.94)29.6817
2010's2 (2.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adeyemi, OO1
Akindele, AJ1
Yemitan, OK1
Aigbe, FR1
Fagbo, FI1
Can, OD1
Ozkay, UD1
Matosiuk, D1
Fidecka, S1
Antkiewicz-Michaluk, L1
Lipkowski, J1
Dybala, I1
Koziol, AE1
Kim, EJ1
Lee, RK1
Suh, JE1
Han, SS1
Kim, JK1
HIRSCH, H1
KOERNER, K1
KAJTOR, F1
BENFEY, BG1
VARMA, DR1
SIMIONOVICI, M1
WINTER, D1
MUELLER, M1
SCHMIEDEL, R1
KATO, R1
VASSANELLI, P1
FRONTINO, G1
CHIESARA, E1
FROMMEL, E1
SEYDOUX, J1
STOICA, I1
Wagner, ER1
Rudzik, AD1
Pradhan, SN1
Wilimowski, M5
Orzechowska-Juzwenko, K2
Barczyńska, J5
Kedzierska-Goździk, L1
Witkowska, M4
Wojewódzki, W4
Duś, E1
Pławiak, T1
Gryska, J1
Maśka, H1
Wahlström, G6
Nordberg, A1
Kruszewska, A1
Langwiński, R1
Szadowska, A1
Mazur, M1
Kamińska, A1
Kusowska, J1
Winer, A1
Koval'skaia, SIa1
Ozeretskovskiĭ, NA1
Veĭsfeĭler, OIu1
Bulatova, AI1
Deloria, LB1
Mannering, GJ1
Bechar, E1
Astroug, H1
Sieklucka-Dziuba, M1
Saczonek, J1
Dziuba, J1
Kleinrok, Z1
Shika, K1
Nakata, C1
Ogura, M1
Tamada, T1
Fujimoto, Y1
Safta, L2
Cuparencu, B2
Kedzierska, L4
Felsztyńska, J3
Garg, BD1
Kourounakis, P1
Tuchweber, B1
Szabo, S1
Kovacs, K1
Misztal, S1
Wiertek, J1
Rogóz, Z1
Hata, T1
Kita, T1
Yoneda, R1
Pálosi, E1
Szporny, L1
Ishii, Y1
Natsugoe, K1
Umezawa, H1
Iorio, LC1
Cohen-Winston, M1
Barnett, A1
Robertson, DW3
Beedle, EE3
Lawson, R2
Leander, JD3
Clark, CR1
Potts, BD1
Parli, CJ1
Krushinski, JH1
Wong, DT1
Rathbun, RC1
Champney, R1
Ferguson, NM1
Ferguson, GG1
Chalabian, ZhA1
Asami, Y1
Otsuka, M1
Hirohashi, T1
Inaba, S1
Yamamoto, H1
Murmann, W1
Almirante, L1
Saccani-Guelfi, M1
Tubaro, E1
Banci, F1
Kimura, R1
Murata, T1
Babbini, M1
Torrielli, MV1
Takagi, K1
Saito, H1
Tsuchiya, M1
Georgiev, V1
Petkov, V1
Petkova, B1
Ostrovskaia, RU1
Parin, VV1
Tsybina, NM1
Engelbrecht, JA1
Long, JP1
Nichols, DE1
Barfknecht, CF1
Hach, B1
Heim, F1
Zaroslinski, JF1
Browne, RK1
Possley, LH1
Prandota, J1
Hoffmann, I1
Kuch, H1
Schmitt, K1
Seidl, G1
Clark, R1
Lynes, TE1
Price, WA1
Smith, DH1
Woodward, JK1
Marvel, JP1
Vernier, VG1
Meeter, E1
Wolthuis, OL1
Trepanier, DL1
Rampy, LW1
Shriver, KL1
Cojocaru, Z1
Pitea, M1
Barzu, T1
Ghiran, D1
Ticsla, I1
Müller, F1
Burger, A1
Siuda, JF1
Rümke, CL1
Noordhoek, J1
Pelczarska, A1
Furgiuele, AR1
High, JP1
Horovitz, ZP1
Lanciault, G1
Wolf, HH1
Manian, AA1
Efron, DH1
Goldberg, ME1
Iwainsky, H1
Wiezorek, WD1

Other Studies

68 other studies available for hexobarbital and Seizures

ArticleYear
Anticonvulsant, anxiolytic and sedative activities of the aqueous root extract of Securidaca longepedunculata Fresen.
    Journal of ethnopharmacology, 2010, Jul-20, Volume: 130, Issue:2

    Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Disease Model

2010
Effects of Hypericum montbretti extract on the central nervous system and involvement of GABA (A)/Benzodiazepine receptors in its pharmacological activity.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:11

    Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System; Diazepam; Exploratory Behavior;

2012
Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine: part 2. Synthesis and pharmacological activity of 1,6-diaryl-5,7(1H)dioxo-2,3-dihydroimidazo[1,2-a][1,3,5]triazines.
    European journal of medicinal chemistry, 2002, Volume: 37, Issue:9

    Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Behavior, Animal; Binding, Competitive; Body Tempe

2002
Safety pharmacology of CKD-602, a novel anticancer agent.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:4

    Topics: Analgesics; Animals; Anticonvulsants; Antineoplastic Agents, Phytogenic; Behavior, Animal; Body Temp

2003
[CONVULSION ACTIVITY IN HYPOTHERMIA].
    Der Anaesthesist, 1964, Volume: 13

    Topics: Anesthesia; Brain; Cats; Electroencephalography; Electrophysiology; Epilepsy; Hexobarbital; Hypother

1964
THE ROLE OF THE DEPTH OF BARBITURATE ANAESTHESIA AND SENSORY STIMULATION IN "SLEEP ACTIVATION".
    Thrombosis et diathesis haemorrhagica, 1964, Apr-15, Volume: 11

    Topics: Anesthesia; Brain; Electroencephalography; Electrophysiology; Epilepsy; Epilepsy, Temporal Lobe; Hex

1964
INFLUENCE OF METHYLDOPA ON CENTRAL EFFECTS OF RESERPINE.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Anesthesia; Animals; Birds; Brain; Brain Chemistry; Chlorpromazine; Hexobarbital; Hypnotics and Seda

1964
[THE CENTRAL STIMULATING ACTION OF DIETHYLPROPION IN COMPARISON WITH PHENMETRAZINE AND RACEMIC BENZEDRINE].
    Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149

    Topics: Amphetamine; Amphetamines; Behavior, Animal; Blood Pressure; Body Temperature Regulation; Central Ne

1964
[ANTICONVULSIVE EFFECTS OF OXINDOL AND DIOXINDOL].
    Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 11

    Topics: Anesthesia; Anesthesiology; Anticonvulsants; Azoles; Electroshock; Hexobarbital; Imides; Indoles; Mi

1964
VARIATION IN THE ACTIVITY OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYMES IN RATS IN RELATION TO THE AGE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Aging; Animals, Newborn; Carisoprodol; Diphosphates; Hexobarbital; Insecticides; Liver; Meprobamate;

1964
STUDY OF THE EFFECTS OF MORPHINE AND NALORPHINE.
    Archives internationales de pharmacodynamie et de therapie, 1964, Nov-01, Volume: 152

    Topics: Animals; Body Temperature Regulation; Chlordiazepoxide; Chlorpromazine; Electroshock; Ether; Guinea

1964
RAPID ELECTROENCEPHALOGRAPHIC ACTIVATION BY SMALL DOSES OF NATRIUM-EVIPAN.
    Epilepsia, 1965, Volume: 6

    Topics: Brain Diseases; Electroencephalography; Epilepsy; Hexobarbital; Humans; Hyperventilation; Migraine D

1965
The anticonvulsant activity of 4-alpha,8-alpha-naphthalenedicarboximide and its derivatives.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:4

    Topics: Animals; Behavior, Animal; Chemistry, Organic; Electric Stimulation; Electrophysiology; Electroshock

1967
Pharmacology of some synthetic tetrahydrocannabinols.
    Neuroscience and biobehavioral reviews, 1984,Fall, Volume: 8, Issue:3

    Topics: Animals; Arousal; Behavior, Animal; Blood Pressure; Cardiovascular System; Cats; Central Nervous Sys

1984
Pharmacological properties of new heterocyclic derivatives of 1,5-benzodiazepine.
    Polish journal of pharmacology and pharmacy, 1983, Volume: 35, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Dihydroxyphenylalanine; Drug Interactions; Female; He

1983
Interaction between spontaneous and electrically induced convulsions and their short- and long-term effects in the abstinence after chronic barbital treatment in the rat.
    Brain research, 1983, May-05, Volume: 266, Issue:2

    Topics: Animals; Electroshock; Hexobarbital; Male; Rats; Rats, Inbred Strains; Seizures; Time Factors

1983
Tolerance, physical dependence and changes in muscarinic receptor binding sites after chronic ethanol treatment in the rat.
    Life sciences, 1982, Jul-19, Volume: 31, Issue:3

    Topics: Alcoholism; Animals; Atropine; Binding Sites; Body Weight; Drug Tolerance; Hexobarbital; Humans; Mal

1982
[Preliminary pharmacological studies on 6 new derivatives of 5-phenylimidazoline].
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1981, Volume: 36

    Topics: Animals; Convulsants; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Imidazoles; Mice; Mice,

1981
[Effect of new pyrazolo-(1,2-a)-1,2,5-triazepine derivatives on the central nervous system].
    Acta poloniae pharmaceutica, 1982, Volume: 39, Issue:5-6

    Topics: Animals; Anticonvulsants; Azepines; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Mice; Mic

1982
[Advantages of using pharmacologic tests to characterize bacterial vaccines].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1980, Issue:7

    Topics: Animals; Bacterial Vaccines; Diphtheria Toxoid; Hexobarbital; Humans; Mice; Pertussis Vaccine; Seizu

1980
Interferon induces sleep and other CNS responses in mice recovering from hexobarbital anesthesia.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Anesthesia, General; Animals; Hexobarbital; Humans; Interferon Type I; Interferon-gamma; Male; Mice;

1993
Synthesis and pharmacological activity of two derivatives of the amide of valproic acid.
    Archiv der Pharmazie, 1997, Volume: 330, Issue:9-10

    Topics: Animals; Anticonvulsants; Hexobarbital; Hypnotics and Sedatives; Locomotion; Male; Mice; Seizures; S

1997
Central action of some cytostatics--methotrexate (MTX) and doxorubicin (DXR). II. The influence on the seizure activity and the learning and memory processes in mice.
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1998, Volume: 53

    Topics: Animals; Brain; Doxorubicin; Drug Interactions; Female; gamma-Aminobutyric Acid; Hexobarbital; Learn

1998
[Inhibitory effects of methyl o-(4-hydroxy-3-methoxycinnamoyl) reserpate (CD-3400) on the central nervous system (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:7

    Topics: Agonistic Behavior; Animals; Avoidance Learning; Blepharoptosis; Body Temperature; Cats; Central Ner

1977
Some central nervous actions of centrophenoxine (Meclofenoxat) in animals.
    Acta biologica et medica Germanica, 1978, Volume: 37, Issue:8

    Topics: Anesthesia; Animals; Antidepressive Agents; Behavior, Animal; Central Nervous System Stimulants; Dru

1978
The effects of atropine on the tolerance and the convulsions seen after withdrawal from forced barbital drinking in the rat.
    Psychopharmacology, 1978, Oct-31, Volume: 59, Issue:2

    Topics: Animals; Atropine; Barbital; Barbiturates; Drug Tolerance; Electroencephalography; Hexobarbital; Hum

1978
Central action of new imido derivatives of succinic acid.
    Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:3

    Topics: Amphetamine; Analgesics; Animals; Brain; Chloral Hydrate; Drug Synergism; Female; Hexobarbital; Levo

1979
Central action of new derivatives of tetrahydropirimidinedione-4,6.
    Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:3

    Topics: Amphetamine; Analgesics; Animals; Brain; Chloral Hydrate; Drug Synergism; Female; Furans; Hexobarbit

1979
The interaction between electrically induced convulsions and tolerance in the abstinence period after chronic barbital treatments in the rat.
    Psychopharmacology, 1976, Aug-17, Volume: 48, Issue:3

    Topics: Animals; Barbital; Barbiturates; Drug Tolerance; Electroshock; Hexobarbital; Humans; Male; Rats; Sei

1976
The interaction between pilocarpine and hexobarbital in male rats.
    Psychopharmacology, 1976, Sep-17, Volume: 49, Issue:2

    Topics: Anesthesia; Animals; Drug Interactions; Drug Tolerance; Hexobarbital; Male; Pilocarpine; Rats; Seizu

1976
Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 227, Issue:2

    Topics: Animals; Digitoxin; Drug Interactions; Ethionine; Female; Hexobarbital; In Vitro Techniques; Liver;

1977
Synthesis and pharmacologic properties of pyridoyl derivatives of 3-methylaminoindole 2-methyltryptamine and isotryptamine.
    Archivum immunologiae et therapiae experimentalis, 1976, Volume: 24, Issue:6

    Topics: Analgesia; Animals; Body Temperature; Dextroamphetamine; Drug Interactions; Female; Hexobarbital; In

1976
The interaction between spontaneous convulsions and tolerance to hexobarbital in the abstinence after chronic barbital treatments in the rat.
    Life sciences, 1976, Dec-15, Volume: 19, Issue:12

    Topics: Animals; Barbital; Barbiturates; Drug Tolerance; Hexobarbital; Humans; Male; Rats; Seizures; Substan

1976
[Central activity, antihypertensive action and antiulcerogenic effects of neurotropin].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:7

    Topics: Acetylcholine; Animals; Anti-Ulcer Agents; Antihypertensive Agents; Anura; Astacoidea; Blood Pressur

1976
Effects of ethyl apovincaminate on the central nervous system.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:10a

    Topics: Animals; Brain; Female; Hexobarbital; Lethal Dose 50; Male; Mice; Motor Activity; Rats; Seizures; Sl

1976
Central action of 2-amino- and 2-amino-5-aryltetrahydropyrimidinediones-4,6.
    Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:4

    Topics: Amphetamine; Analgesia; Animals; Central Nervous System; Dihydroxyphenylalanine; Drug Synergism; Fem

1975
Pharmacological action of FD-008, a new dopamine-beta-hydroxylase inhibitor.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2

    Topics: Administration, Oral; Aldehyde Oxidoreductases; Animals; Avoidance Learning; Body Temperature; Depre

1975
Interaction studies in mice of SCH 29851, a potential non-sedating antihistamine, with commonly used therapeutic agents.
    Agents and actions, 1986, Volume: 18, Issue:5-6

    Topics: Animals; Benzhydryl Compounds; Diphenhydramine; Dose-Response Relationship, Drug; Electroshock; Hexo

1986
Imidazole anticonvulsants: structure-activity relationships of [(biphenylyloxy)alkyl]imidazoles.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Animals; Biphenyl Compounds; Chemical Phenomena; Chemistry; Drug Synergism; Hexobarbital; Imidazoles

1987
Discovery and anticonvulsant activity of the potent metabolic inhibitor 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethylbenzamide.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Acetylation; Administration, Oral; Animals; Anticonvulsants; Benzamides; Dose-Response Relationship,

1987
Structure-activity relationships of (arylalkyl)imidazole anticonvulsants: comparison of the (fluorenylalkyl)imidazoles with nafimidone and denzimol.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Anticonvulsants; Cerebral Cortex; Chemical Phenomena; Chemistry; Drug Synergism; Female; Fl

1986
Selected pharmacological studies of Luffa operculata.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:6

    Topics: Analgesics; Animals; Blood Pressure; Electrocardiography; Electroshock; Foot; Hexobarbital; Histamin

1974
[Change in the activity of a cell-free protein-synthesizing system with different functional states of the central nervous system].
    Voprosy meditsinskoi khimii, 1972, Volume: 18, Issue:2

    Topics: Anesthesia; Animals; Brain; Cell-Free System; Chlorpromazine; gamma-Aminobutyric Acid; Hexobarbital;

1972
The synthesis and pharmacology of a novel benzodiazepine derivative, 1-methyl-5-(o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(ID-540).
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:10

    Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Bemegride; Benzodiazepinones; Cats; Chlo

1974
Effects of hexobarbitone, ether, morphine, and urethane upon the acute toxicity of propranolol and D-(--)-INPEA.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:10

    Topics: Amino Alcohols; Animals; Atropine; Bradycardia; Central Nervous System; Drug Synergism; Ethers; Hear

1966
Pharmacology of a nicotinamido-methylaminopyrazolone (Ra 101).
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Carrageena

1970
Influence of alkylamides of glutamic acid and related compounds on the central nervous system. I. Central depressant effect of theanine.
    Chemical & pharmaceutical bulletin, 1971, Volume: 19, Issue:6

    Topics: Amides; Amino Acids; Animals; Bemegride; Brain; Brain Chemistry; Caffeine; Carbon Isotopes; Central

1971
Investigation on pharmacological properties of hexadiphane, oxazepam hemisuccinate and of their combination.
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:6

    Topics: Animals; Azepines; Benzene Derivatives; Diphenylacetic Acids; Drug Synergism; Female; Gallbladder; G

1972
Pharmacological studies of Panax Ginseng root: pharmacological properties of a crude saponin fraction.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:3

    Topics: Acetates; Acetylcholine; Animals; Behavior, Animal; Central Nervous System; Digestive System; Drug S

1972
Central effects of a series of N1-, N4-acyl piperazine derivatives.
    Acta physiologica et pharmacologica Bulgarica, 1974, Volume: 1

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Evoked Potentials; Female; Hexobarbital; Humans; Lethal

1974
[Comparative neurotropic activity of gamma-aminobutyric acid and its cetylic ester].
    Biulleten' eksperimental'noi biologii i meditsiny, 1972, Volume: 73, Issue:1

    Topics: Aminobutyrates; Analgesics; Animals; Barbiturates; Cats; Cerebral Cortex; Drug Synergism; Hexobarbit

1972
Pharmacologic evaluation of 3,4-dimethoxyphenylpropenes and 3,4-dimethoxyphenylpropanediols.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 199, Issue:2

    Topics: Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions;

1972
[Comparative studieson the central stimulating effects of caffeie and chlorogenic acid in white mice].
    Arzneimittel-Forschung, 1971, Volume: 2

    Topics: Animals; Caffeine; Chlorogenic Acid; Drug Antagonism; Hexobarbital; Male; Mice; Movement; Oxygen Con

1971
Propylene glycol as a drug solvent in pharmacologic studies.
    Toxicology and applied pharmacology, 1971, Volume: 19, Issue:4

    Topics: Animals; Anticonvulsants; Drug Interactions; Hexobarbital; Mice; Motor Activity; Phenobarbital; Prop

1971
Pharmacologic properties of derivatives of 3-phenyl-3-hydroxyglutaric acid.
    Archivum immunologiae et therapiae experimentalis, 1970, Volume: 18, Issue:2

    Topics: Animals; Azoles; Blood Pressure; Chloral Hydrate; Drug Antagonism; Drug Synergism; Glutarates; Hexob

1970
[2-ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine, a new psychotropic compound].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Aggression; Alcohols; Animals; Behavior, Animal; Central Nervous System; Chemistry, Pharmaceutical;

1970
The pharmacology and toxicology of midaflur.
    Toxicology and applied pharmacology, 1971, Volume: 18, Issue:4

    Topics: Analgesics; Animals; Appetite; Avoidance Learning; Benzimidazoles; Body Temperature; Body Weight; Ca

1971
The effects of cholinesterase inhibitors on the body temperature of the rat.
    European journal of pharmacology, 1968, Volume: 4, Issue:1

    Topics: Animals; Body Temperature Regulation; Cholinesterase Inhibitors; Cold Temperature; Depression, Chemi

1968
Chemistry and pharmacology of a series of substituted 4H-pyrazino[1,2-a]pyrimidin-4-ones.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:5

    Topics: Alkylation; Amphetamine; Animals; Central Nervous System; Drug Antagonism; Drug Synergism; Hexobarbi

1968
[Pharmacologic study of certain sulfhydrazide and diacylhydrazine derivatives].
    Journal de physiologie, 1968, Volume: 60 Suppl 2

    Topics: Animals; Barbiturates; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Hexobarbital; Hydraz

1968
[Contribution on the INH poisoning].
    Zeitschrift fur Tuberkulose und Erkrankungen der Thoraxorgane, 1968, Volume: 127, Issue:5

    Topics: Aged; Hexobarbital; Humans; Infusions, Parenteral; Isoniazid; Male; Medication Errors; Middle Aged;

1968
o,o'-Disubstituted phenylcyclopropylamines.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:2

    Topics: Amphetamine; Animals; Blepharoptosis; Hexobarbital; Imipramine; Mice; Motor Activity; Propylamines;

1969
The influence of lynestrenol on the rate of metabolism of phenobarbital, phenytoin and hexobarbital in mice.
    European journal of pharmacology, 1969, Volume: 6, Issue:2

    Topics: Animals; Bemegride; Electroshock; Enzyme Induction; Female; Hexobarbital; Lynestrenol; Male; Mice; P

1969
On the central action of some oxoindole compounds.
    Archivum immunologiae et therapiae experimentalis, 1969, Volume: 17, Issue:1

    Topics: Absorption; Amphetamine; Animals; Blood Pressure; Central Nervous System; Depression; Drug Antagonis

1969
Some central effects of SQ 10,643 [2'3-(-dimethlaminopropylthio) cinnamanilide hydrochloride], a potent serotonin antagonist.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:1

    Topics: Animals; Avoidance Learning; Behavior, Animal; Body Temperature; Cats; Electroconvulsive Therapy; El

1965
Some neuropharmacological properties of the ephedrine isomers.
    Journal of pharmaceutical sciences, 1965, Volume: 54, Issue:6

    Topics: Amphetamine; Central Nervous System; Ephedrine; Hexobarbital; Seizures

1965
A comparative pharmacological study of a series of monohydroxylated and methoxylated chlorpromazine derivatives.
    Life sciences, 1965, Volume: 4, Issue:24

    Topics: Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Electroconvulsive Therapy; Hexobarbit

1965
[Acute isoniazid poisoning. Points of onset in the macro-organism, symptoms and measures of treatment].
    Beitrage zur Klinik und Erforschung der Tuberkulose und der Lungenkrankheiten, 1965, Dec-30, Volume: 131, Issue:5

    Topics: Amino Acids; Ammonia; Animals; Barbiturates; Biochemical Phenomena; Biochemistry; Blood; Hexobarbita

1965