carbetapentane has been researched along with Seizures in 3 studies
carbetapentane: RN given refers to parent cpd
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Structure-activity relationships of analogues in which the ester function and cyclopentane moieties were modified have been investigated by evaluating their ability to prevent seizures in the rat maximal electroshock test." | 3.68 | Novel 1-phenylcycloalkanecarboxylic acid derivatives as potential anticonvulsant agents. ( Calderon, SN; Newman, AH; Tortella, FC, 1991) |
| "The non-opioid antitussives dextromethorphan and carbetapentane, the active ingredients of several over-the-counter cough suppressants, provide a dose-related protection against maximal electroshock seizures in rats." | 3.67 | Dextromethorphan and carbetapentane: centrally acting non-opioid antitussive agents with novel anticonvulsant properties. ( Musacchio, JM; Tortella, FC, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calderon, SN | 1 |
| Newman, AH | 1 |
| Tortella, FC | 2 |
| Kim, HC | 1 |
| Jhoo, WK | 1 |
| Kim, WK | 1 |
| Shin, EJ | 1 |
| Cheon, MA | 1 |
| Shin, CY | 1 |
| Ko, KH | 1 |
| Musacchio, JM | 1 |
3 other studies available for carbetapentane and Seizures
| Article | Year |
|---|---|
Novel 1-phenylcycloalkanecarboxylic acid derivatives as potential anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carboxylic Acids; Cyclopentanes; Male; Rats; Rats, Inbred Strains; Seizure | 1991 |
Carbetapentane attenuates kainate-induced seizures via sigma-1 receptor modulation.
Topics: Animals; Benzoxazines; Brain; Cells, Cultured; Cyclopentanes; Drug Interactions; Immunohistochemistr | 2001 |
Dextromethorphan and carbetapentane: centrally acting non-opioid antitussive agents with novel anticonvulsant properties.
Topics: Animals; Anticonvulsants; Antitussive Agents; Cyclopentanes; Dextromethorphan; Drug Synergism; Elect | 1986 |