arecoline has been researched along with Seizures in 8 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A tropane ester, three tropane ethers, atropine and mecamylamine were compared in mice for their anti-muscarinic and anti-nicotinic activity against arecoline-induced tremor and nicotine-induced convulsions, respectively." | 3.69 | Anticholinergic activity in mice and receptor-binding properties in rats of a series of synthetic tropane derivatives. ( Cui, WY; Gao, ZG; Liu, BY; Liu, CG; Wang, L, 1997) |
| "In an attempt to know the relation of seizure and gastric mucosal damage, we challenged arecoline (ACL) centrally to induce seizure and investigated gastric hemorrhagic injury in acid-irrigated stomachs of rats." | 1.31 | Gastric mucosal damage induced by arecoline seizure in rats. ( Cheng, JT; Hung, CR; Shih, CS, 2000) |
| "Haloperidol-induced catalepsy was potentiated in DSP-4 treated rats, while arecoline-induced catalepsy was attenuated." | 1.26 | Alterations in drug induced catalepsy and post-decapitation convulsions following brain and spinal cord depletion of norepinephrine by the neurotoxin DSP-4. ( Asin, KE; Fibiger, HC; Wirtshafter, D, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basselin, M | 1 |
| Chang, L | 1 |
| Seemann, R | 1 |
| Bell, JM | 1 |
| Rapoport, SI | 1 |
| Asin, KE | 1 |
| Wirtshafter, D | 1 |
| Fibiger, HC | 1 |
| Gao, ZG | 1 |
| Cui, WY | 1 |
| Liu, BY | 1 |
| Liu, CG | 1 |
| Wang, L | 1 |
| Hung, CR | 1 |
| Cheng, JT | 1 |
| Shih, CS | 1 |
| Lazarova, M | 2 |
| Roussinov, K | 2 |
| Lodge, D | 1 |
| Johnston, GA | 1 |
| Curtis, DR | 1 |
| Brand, SJ | 1 |
| Witkin, JM | 1 |
| Alvarado-Garcia, R | 1 |
| Lee, MA | 1 |
| Witkin, KM | 1 |
8 other studies available for arecoline and Seizures
| Article | Year |
|---|---|
Chronic lithium administration potentiates brain arachidonic acid signaling at rest and during cholinergic activation in awake rats.
Topics: Animals; Arachidonic Acid; Arecoline; Autoradiography; Body Weight; Brain; Carbon Radioisotopes; Cho | 2003 |
Alterations in drug induced catalepsy and post-decapitation convulsions following brain and spinal cord depletion of norepinephrine by the neurotoxin DSP-4.
Topics: Amines; Animals; Arecoline; Benzylamines; Brain; Catalepsy; Drug Interactions; Haloperidol; Humans; | 1982 |
Anticholinergic activity in mice and receptor-binding properties in rats of a series of synthetic tropane derivatives.
Topics: Animals; Arecoline; Brain; Drug Antagonism; Female; Male; Mice; Muscarinic Agonists; Muscarinic Anta | 1997 |
Gastric mucosal damage induced by arecoline seizure in rats.
Topics: Animals; Arecoline; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; | 2000 |
On some relationships between gamma-aminobutyric acid (GABA) and the cholinergic mechanisms in electric convulsions.
Topics: Aminobutyrates; Animals; Arecoline; Diphenylacetic Acids; Electric Stimulation; gamma-Aminobutyric A | 1977 |
On some relationships between gamma-aminobutyric acid (GABA) and the cholinergic mechanisms in pentylenetetrazol convulsions.
Topics: Aminobutyrates; Animals; Arecoline; gamma-Aminobutyric Acid; Male; Mice; Parasympathetic Nervous Sys | 1977 |
Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system.
Topics: Action Potentials; Alanine; Aminobutyrates; Animals; Areca; Arecoline; Bicuculline; Cats; Cerebellum | 1977 |
Nonmuscarinic neurotoxicity of oxotremorine.
Topics: Animals; Arecoline; Atropine; Atropine Derivatives; Benactyzine; Benztropine; Crying; Diazepam; Dose | 1987 |