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bromouracil and Seizures

bromouracil has been researched along with Seizures in 1 studies

Bromouracil: 5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.
5-bromouracil : A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
" The anesthesia induced by 1-amino-5-bromouracil was potentiated by diazepam, pentobarbital, and muscimol, and was antagonized by picrotoxin but not by bicuculline."3.69Effects of 1-amino-5-bromouracil on the benzodiazepine-GABAA receptor complex. ( Imaizumi, M; Machida, H; Miyazaki, S, 1994)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyazaki, S1
Imaizumi, M1
Machida, H1

Other Studies

1 other study available for bromouracil and Seizures

ArticleYear
Effects of 1-amino-5-bromouracil on the benzodiazepine-GABAA receptor complex.
    European journal of pharmacology, 1994, Dec-12, Volume: 271, Issue:1

    Topics: Anesthesia; Animals; Anti-Anxiety Agents; Anticonvulsants; Bridged Bicyclo Compounds; Bridged Bicycl

1994