1-aminoindan-1,5-dicarboxylic acid has been researched along with Seizures in 4 studies
1-aminoindan-1,5-dicarboxylic acid: structure given in first source
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was undertaken to clarify the effect of group I metabotropic glutamate receptor (mGluR) antagonist, (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA) on pentetrazol-induced kindled seizures." | 7.76 | Anticonvulsant effect of (RS)-1-aminoindan-1,5-dicarboxylic acid on pentetrazol-induced kindled seizures in mice. ( Kaida, Y; Kamei, C; Takechi, K; Watanabe, Y, 2010) |
| "The present study was undertaken to clarify the effect of group I metabotropic glutamate receptor (mGluR) antagonist, (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA) on pentetrazol-induced kindled seizures." | 3.76 | Anticonvulsant effect of (RS)-1-aminoindan-1,5-dicarboxylic acid on pentetrazol-induced kindled seizures in mice. ( Kaida, Y; Kamei, C; Takechi, K; Watanabe, Y, 2010) |
| "In the developing animal, intraperitoneal injections of kainic acid (KA) lead to a prolonged initial seizure followed by chronic recurrent seizures and long-term hippocampal dysfunction." | 3.71 | AIDA, a class I metabotropic glutamate-receptor antagonist limits kainate-induced hippocampal dysfunction. ( Carmant, L; Emond, M; Meilleur, S; Psarropoulou, C; Renaud, J, 2002) |
| " The group I mGluR antagonist 1-aminoindan-1,5-dicarboxylic acid (AIDA) dose-dependently antagonised PTZ-induced seizures with a mean ED50 value of 465 nmol." | 3.70 | Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice. ( Dalby, NO; Thomsen, C, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, Y | 1 |
| Kaida, Y | 1 |
| Takechi, K | 1 |
| Kamei, C | 1 |
| Renaud, J | 1 |
| Emond, M | 1 |
| Meilleur, S | 1 |
| Psarropoulou, C | 1 |
| Carmant, L | 1 |
| Thomsen, C | 1 |
| Dalby, NO | 1 |
| Chapman, AG | 1 |
| Yip, PK | 1 |
| Yap, JS | 1 |
| Quinn, LP | 1 |
| Tang, E | 1 |
| Harris, JR | 1 |
| Meldrum, BS | 1 |
4 other studies available for 1-aminoindan-1,5-dicarboxylic acid and Seizures
| Article | Year |
|---|---|
Anticonvulsant effect of (RS)-1-aminoindan-1,5-dicarboxylic acid on pentetrazol-induced kindled seizures in mice.
Topics: Animals; Anticonvulsants; Brain; Excitatory Amino Acid Antagonists; GABA Agents; Indans; Kindling, N | 2010 |
AIDA, a class I metabotropic glutamate-receptor antagonist limits kainate-induced hippocampal dysfunction.
Topics: Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Indans; Kainic Acid; Mal | 2002 |
Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice.
Topics: Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Indans; Infu | 1998 |
Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid).
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzoates; Dose-Response Relationship, Drug; Epileps | 1999 |