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isoproterenol and Seizures

isoproterenol has been researched along with Seizures in 32 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined."7.70Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. ( Chisaki, K; Hayashi, H; Komatsu, Y; Sanae, F, 1999)
"The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice."7.69Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997)
"The electrocardiogram was recorded and serum and bulk myocardial electrolytes were determined in male Sprague Dawley rats, subjected to dietary magnesium deficiency for various periods, to assess the time course of development and cessation of the enhanced arrhythmogenic action of isoproterenol (150 micrograms/kg, subcutaneously) and to establish possible relationships between electrolyte changes and severe ventricular dysrhythmias."7.67Enhanced incidence of isoproterenol-induced ventricular fibrillation in the magnesium-deficient rat. ( Guideri, G; Horowitz, S; Lehr, D, 1985)
"Pretreatment with propranolol increased the time-to-seizure by 70% and practolol by 50% without altering gross lung appearance or lung wet wt/dry wt."5.27Beta adrenergic receptors and glucagon in seizures from exposure to oxygen at high pressure (OHP). ( Beckman, DL; Crittenden, DJ, 1983)
" Potential cerebroprotective vascular effects of CORM-A1 (2 mg/kg ip, 30 min before seizures) were tested 2 days after bicuculline-induced epileptic seizures (late postictal period)."3.74Cerebroprotective effects of the CO-releasing molecule CORM-A1 against seizure-induced neonatal vascular injury. ( Fedinec, AL; Leffler, CW; Parfenova, H; Tcheranova, D; Zimmermann, A, 2007)
" All 12 symptomatic patients and 1 asymptomatic sibling (mean age, 13+/-7 years) were found to have a relative resting bradycardia (64+/-13 bpm, versus 93+/-12 bpm in the unaffected siblings), as well as PVT induced by treadmill or isoproterenol infusion and appearing at a mean sinus rate of 110+/-10 bpm."3.71Autosomal recessive catecholamine- or exercise-induced polymorphic ventricular tachycardia: clinical features and assignment of the disease gene to chromosome 1p13-21. ( Bahan, T; Eldar, M; Friedman, E; Goldman, B; Kastner, DL; Khoury, A; Lahat, H; Levy-Nissenbaum, E; Lorber, A; Pras, E, 2001)
"Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined."3.70Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. ( Chisaki, K; Hayashi, H; Komatsu, Y; Sanae, F, 1999)
"The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice."3.69Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997)
"Upright tilt table testing combined with isoproterenol infusion may be useful to distinguish convulsive syncope from epileptic seizures."3.68Differentiation of convulsive syncope and epilepsy with head-up tilt testing. ( Elliott, L; Gerard, G; Grubb, BP; Hahn, H; Roush, K; Spann, C; Temesy-Armos, P, 1991)
"The electrocardiogram was recorded and serum and bulk myocardial electrolytes were determined in male Sprague Dawley rats, subjected to dietary magnesium deficiency for various periods, to assess the time course of development and cessation of the enhanced arrhythmogenic action of isoproterenol (150 micrograms/kg, subcutaneously) and to establish possible relationships between electrolyte changes and severe ventricular dysrhythmias."3.67Enhanced incidence of isoproterenol-induced ventricular fibrillation in the magnesium-deficient rat. ( Guideri, G; Horowitz, S; Lehr, D, 1985)
" All patients suffering from Stokes-Adams seizures were first given a trial period of conservative therapy, including isoproterenol (Isuprel), ephedrine, atropine and steroids."3.64THE IMPLANTABLE CARDIAC PACEMAKER. ( BIGELOW, WG; HEIMBECKER, RO; TRIMBLE, AS, 1964)
"We hypothesized that seizures cause prolonged postictal cerebral vascular dysfunction that can be accentuated by HO inhibition and rescued by HO overexpression."1.33Epileptic seizures cause extended postictal cerebral vascular dysfunction that is prevented by HO-1 overexpression. ( Carratu, P; Fedinec, A; Leffler, CW; Parfenova, H; Pourcyrous, M; Tcheranova, D, 2005)
"Motor activity occurring during neurocardiogenic syncope can mimic true neurologic events."1.32Clinical spectrum and prevalence of neurologic events provoked by tilt table testing. ( Goldberger, J; Horvath, G; Kadish, A; Kruse, J; Passman, R; Shah, A; Thomas, J, 2003)
"The syncope or presyncope was not induced by head-up tilt testing."1.31Successful treatment of malignant neurocardiogenic syncope with repeated tilt training program. ( Abe, H; Kohshi, K; Nagatomo, T; Nakashima, Y; Numata, T; Sonoda, S, 2000)
"Infective myocarditis is likely to be the cause of the disease even if the pathogen agent cannot always be identified."1.31[Therapy and prognosis of infectious complete atrioventricular block in children]. ( Batmaz, G; Bonnet, D; Fraisse, A; Iserin, L; Kachaner, J; Villain, E, 2000)
"To assess whether electrically induced seizures are indeed required for the appearance of the blunted pineal response to isoproterenol, pineal and serum melatonin levels were measured after isoproterenol stimulation in rats treated with ECS (80 mA, 0."1.29Role of seizure activity in the decreased pineal response to isoproterenol in rats chronically treated with electroconvulsive shock. ( Amaro, S; d'Istria, M; De Luca, B; Maj, M; Monteleone, P; Serino, I, 1994)
"Treatment with propranolol or isoproterenol did not have any effect on convulsive activity of PINX gerbils, except that isoproterenol increased the excitability of all the gerbils."1.28Noradrenergic involvement in pinealectomy induced convulsions in gerbils. ( Champney, TH, 1990)
"Like 1 and 2, tonic-clonic seizures were induced when trans-3 or -4 were administered to mice intracerebroventricularly."1.27Stereoselective syntheses of the trans-decahydroquinoline-5-carboxylic acid epimers. Diastereomeric zwitterionic probes of gamma-aminobutyric acid related biological properties in vitro and in vivo. ( Enna, SJ; Fung, YK; Patch, RJ; Witiak, DT, 1986)
"Pretreatment with propranolol increased the time-to-seizure by 70% and practolol by 50% without altering gross lung appearance or lung wet wt/dry wt."1.27Beta adrenergic receptors and glucagon in seizures from exposure to oxygen at high pressure (OHP). ( Beckman, DL; Crittenden, DJ, 1983)
"The child had asystole and grand mal seizures associated with lidocaine serum concentration of 19."1.27Intravenous lidocaine overdosage in a child. ( Edgren, B; Gehrz, R; Tilelli, J, 1986)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199020 (62.50)18.7374
1990's5 (15.63)18.2507
2000's7 (21.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Witiak, DT1
Patch, RJ1
Enna, SJ1
Fung, YK1
Botion, LM1
Doretto, MC1
Passman, R1
Horvath, G1
Thomas, J1
Kruse, J1
Shah, A1
Goldberger, J1
Kadish, A1
LEE, JK1
TRIMBLE, AS1
HEIMBECKER, RO1
BIGELOW, WG1
KONG, Y1
HEYMAN, A1
ENTMAN, ML1
MCINTOSH, HD1
MATTHEWS, RJ1
Parfenova, H2
Carratu, P1
Tcheranova, D2
Fedinec, A1
Pourcyrous, M1
Leffler, CW2
Zimmermann, A1
Fedinec, AL1
Crittenden, DJ1
Beckman, DL1
Halloran, TJ1
Phillips, CE1
Monteleone, P1
Amaro, S1
De Luca, B1
d'Istria, M1
Serino, I1
Maj, M1
Amabeoku, GJ1
Syce, JA1
Sanae, F1
Hayashi, H1
Chisaki, K1
Komatsu, Y1
Numata, T1
Abe, H1
Nagatomo, T1
Sonoda, S1
Kohshi, K1
Nakashima, Y1
Batmaz, G1
Villain, E1
Bonnet, D1
Iserin, L1
Fraisse, A1
Kachaner, J1
Lahat, H1
Eldar, M1
Levy-Nissenbaum, E1
Bahan, T1
Friedman, E1
Khoury, A1
Lorber, A1
Kastner, DL1
Goldman, B1
Pras, E1
Sabelli, HC1
Diamond, BI1
May, J1
Havdala, HS1
Georgiev, VP1
Petkova-Radkova, BP1
Hayler, AM1
Holt, DW1
O'Keeffe, B1
Medd, RK1
García Sacristán, A1
Illera Martín, M1
Sanz Sánchez, F1
Assem, ES1
D'Mello, A1
Wieczorek, WJ1
Greenberg, R1
Smorong, K1
Grubb, BP1
Gerard, G1
Roush, K1
Temesy-Armos, P1
Elliott, L1
Hahn, H1
Spann, C1
Champney, TH1
Edgren, B1
Tilelli, J1
Gehrz, R1
Guideri, G1
Lehr, D1
Horowitz, S1
Kellner, M1
Maklári, E1
Kovách, AG1
Mennear, JH1
Rudzik, AD1
Murray, JD1
Fleming, P1
Weber, J1
Hsuen, J1
Bannatyne, R1
Anglin, C1
Strauer, BE1
Brunner, L1
Dehne, N1
Raison, JC1
Osborn, JJ1
Beaumont, JO1
Gerbode, F1

Reviews

1 review available for isoproterenol and Seizures

ArticleYear
The continuing problem of purulent meningitis in infants and children.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:4

    Topics: Bacterial Vaccines; Bicarbonates; Brain Edema; Diagnosis, Differential; Diazepam; Digoxin; Fever; Ga

1974

Other Studies

31 other studies available for isoproterenol and Seizures

ArticleYear
Stereoselective syntheses of the trans-decahydroquinoline-5-carboxylic acid epimers. Diastereomeric zwitterionic probes of gamma-aminobutyric acid related biological properties in vitro and in vivo.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:1

    Topics: Animals; Brain; Chemical Phenomena; Chemistry; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Magnet

1986
Changes in peripheral energy metabolism during audiogenic seizures in rats.
    Physiology & behavior, 2003, Volume: 78, Issue:4-5

    Topics: Acoustic Stimulation; Adipose Tissue; Adrenergic beta-Agonists; Animals; Blood Glucose; Energy Metab

2003
Clinical spectrum and prevalence of neurologic events provoked by tilt table testing.
    Archives of internal medicine, 2003, Sep-08, Volume: 163, Issue:16

    Topics: Adrenergic beta-Agonists; Adult; Aged; Blood Pressure; Diagnosis, Differential; Female; Humans; Isop

2003
Complete atrioventricular block complicated by Adams-Stokes seizures successfully treated with isopropyl noradrenaline (Isuprel).
    Canadian Medical Association journal, 1961, May-06, Volume: 84

    Topics: Anti-Arrhythmia Agents; Atrioventricular Block; Cardiotonic Agents; Heart; Heart Block; Isoprotereno

1961
THE IMPLANTABLE CARDIAC PACEMAKER.
    Canadian Medical Association journal, 1964, Jan-18, Volume: 90

    Topics: Adams-Stokes Syndrome; Atropine; Coronary Disease; Electrocardiography; Geriatrics; Heart Arrest; He

1964
GLOSSOPHARYNGEAL NEURALGIA ASSOCIATED WITH BRADYCARDIA, SYNCOPE, AND SEIZURES.
    Circulation, 1964, Volume: 30

    Topics: Atropine; Bradycardia; Drug Therapy; Electrocardiography; Geriatrics; Glossopharyngeal Nerve; Glosso

1964
PREVENTION OF VENTRICULAR TACHYCARDIA AND STOKES-ADAMS SEIZURES IN COMPLETE HEART BLOCK; TREATMENT WITH LARGE DOSES OF INTRAVENOUS ISOPROTERENOL.
    Archives of internal medicine, 1965, Volume: 116

    Topics: Adams-Stokes Syndrome; Atrial Fibrillation; Drug Therapy; Electrocardiography; Geriatrics; Heart Blo

1965
Epileptic seizures cause extended postictal cerebral vascular dysfunction that is prevented by HO-1 overexpression.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:6

    Topics: Animals; Animals, Newborn; Bradykinin; Cerebrovascular Circulation; Gene Expression Regulation, Enzy

2005
Cerebroprotective effects of the CO-releasing molecule CORM-A1 against seizure-induced neonatal vascular injury.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Administration, Topical; Animals; Animals, Newborn; Bicuculline; Blood Pressure; Boranes; Bradykinin

2007
Beta adrenergic receptors and glucagon in seizures from exposure to oxygen at high pressure (OHP).
    Life sciences, 1983, Nov-14, Volume: 33, Issue:20

    Topics: Animals; Glucagon; Hyperbaric Oxygenation; Isoproterenol; Lung; Male; Practolol; Propranolol; Rats;

1983
Propranolol intoxication. A severe case responding to norepinephrine therapy.
    Archives of internal medicine, 1981, Volume: 141, Issue:6

    Topics: Coma; Female; Half-Life; Humans; Hypotension; Isoproterenol; Middle Aged; Norepinephrine; Propranolo

1981
Role of seizure activity in the decreased pineal response to isoproterenol in rats chronically treated with electroconvulsive shock.
    Psychiatry research, 1994, Volume: 53, Issue:2

    Topics: Animals; Electroshock; Isoproterenol; Male; Melatonin; Norepinephrine; Pineal Gland; Rats; Rats, Spr

1994
Propranolol-induced seizures in mice: the role of noradrenaline.
    Cellular and molecular life sciences : CMLS, 1997, Volume: 53, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; alpha-Methyltyros

1997
Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:3

    Topics: Anesthesia; Animals; Atrial Function, Right; Blood Pressure; Cardiotonic Agents; Central Nervous Sys

1999
Successful treatment of malignant neurocardiogenic syncope with repeated tilt training program.
    Japanese circulation journal, 2000, Volume: 64, Issue:5

    Topics: Electrocardiography; Home Nursing; Humans; Isoproterenol; Male; Middle Aged; Physical Therapy Modali

2000
[Therapy and prognosis of infectious complete atrioventricular block in children].
    Archives des maladies du coeur et des vaisseaux, 2000, Volume: 93, Issue:5

    Topics: Adolescent; Antiviral Agents; Cardiotonic Agents; Child; Child, Preschool; Coxsackievirus Infections

2000
Autosomal recessive catecholamine- or exercise-induced polymorphic ventricular tachycardia: clinical features and assignment of the disease gene to chromosome 1p13-21.
    Circulation, 2001, Jun-12, Volume: 103, Issue:23

    Topics: Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Arabs; Bradycardia; Catecholamine

2001
Differential interactions of phenobarbital and pentobarbital with beta-adrenergic mechanisms in vitro and in vivo.
    Experimental neurology, 1977, Volume: 54, Issue:3

    Topics: Action Potentials; Animals; Anura; Bucladesine; Calcium; Cyclic AMP; Dose-Response Relationship, Dru

1977
Effects of certain drugs connected with the system of 3',5'-cAMP on the picrotoxin convulsive-seizure threshold and on the action of GABA.
    Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles, 1976, Volume: 29, Issue:11

    Topics: Aminobutyrates; Animals; Brain; Bucladesine; Cyclic AMP; Drug Interactions; gamma-Aminobutyric Acid;

1976
Treatment of disopyramide overdosage.
    The Medical journal of Australia, 1979, Mar-24, Volume: 1, Issue:6

    Topics: Antidotes; Bradycardia; Disopyramide; Humans; Isoproterenol; Pyridines; Seizures

1979
[Nor-tropan hydantoins n-substituted: action on smooth muscle, and its antiarrhythmic and anticonvulsant effects (author's transl)].
    Archivos de farmacologia y toxicologia, 1977, Volume: 3, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Drug Evaluation; Hydantoins; Intestines; Isoproter

1977
Enhanced effect of isoprenaline after chronic administration in microanaphylactic shock of guinea-pigs [proceedings].
    British journal of pharmacology, 1976, Volume: 57, Issue:3

    Topics: Anaphylaxis; Animals; Guinea Pigs; Isoproterenol; Male; Ovalbumin; Seizures

1976
The bronchodilator acitivity of an 11-deoxyprostaglandin (AY 23 578).
    Canadian journal of physiology and pharmacology, 1975, Volume: 53, Issue:5

    Topics: Aerosols; Animals; Bronchodilator Agents; Carbachol; Cats; Dose-Response Relationship, Drug; Guinea

1975
Differentiation of convulsive syncope and epilepsy with head-up tilt testing.
    Annals of internal medicine, 1991, Dec-01, Volume: 115, Issue:11

    Topics: Adolescent; Adult; Aged; Bradycardia; Diagnosis, Differential; Electroencephalography; Epilepsy; Eva

1991
Noradrenergic involvement in pinealectomy induced convulsions in gerbils.
    Neuroscience letters, 1990, Dec-11, Volume: 120, Issue:2

    Topics: alpha-Methyltyrosine; Animals; Gerbillinae; Hypothalamus; Isoproterenol; Male; Methyltyrosines; Nore

1990
Intravenous lidocaine overdosage in a child.
    Journal of toxicology. Clinical toxicology, 1986, Volume: 24, Issue:1

    Topics: Child; Dopamine; Glucagon; Half-Life; Humans; Hypotension; Isoproterenol; Kinetics; Lidocaine; Liver

1986
Enhanced incidence of isoproterenol-induced ventricular fibrillation in the magnesium-deficient rat.
    Journal of the American College of Nutrition, 1985, Volume: 4, Issue:2

    Topics: Animals; Calcium; Diet; Disease Susceptibility; Electrocardiography; Electrolytes; Isoproterenol; Ma

1985
Studies in experimental pulmonary oedema. 3. Effect of adrenolytic drugs on epinephrine-induced pulmonary oedema in the rat.
    Acta medica Academiae Scientiarum Hungaricae, 1966, Volume: 23, Issue:1

    Topics: Animals; Brain; Epinephrine; Isoproterenol; Phenoxybenzamine; Pulmonary Edema; Rats; Seizures

1966
Potentiation of the anticonvulsant action of acetazolamide.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:12

    Topics: Acetazolamide; Amphetamine; Animals; Anticonvulsants; Caffeine; Cocaine; Desipramine; Drug Synergism

1966
[Treatment of carotid sinus syndrome with cardiac pacemaker stimulation].
    Deutsche medizinische Wochenschrift (1946), 1973, Mar-16, Volume: 98, Issue:11

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Blood Pressure Determination; Carotid Sinus; Electrocardiograp

1973
Oxygen consumption after open heart surgery neasured by a digital computer system.
    Annals of surgery, 1970, Volume: 171, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Body Temperature; Cardiac Surgical Procedures; Child, P

1970