Page last updated: 2024-10-16

choline and Seizures

choline has been researched along with Seizures in 50 studies

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
") of saline (control) or kainic acid to induce seizures and were euthanized 16 days later."7.77Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood. ( Blusztajn, JK; Glenn, MJ; Mellott, TJ; Tognoni, CM; Williams, CL; Wong-Goodrich, SJ, 2011)
"Prenatal choline supplementation can protect rats against cognitive deficits induced by status epilepticus induced by the cholinergic agent pilocarpine [J."7.71Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus. ( Blusztajn, JK; Cermak, JM; Holmes, GL; Liu, Z; Neill, JC; Sarkisian, MR; Stafstrom, CE; Yang, Y, 2002)
"This study determined the effects of bilateral discrete partial lesions of cholinergic neurons of the laterodorsal tegmental nucleus (LDTg) of the pontomesencephalic tegmentum on seizures induced by intravenous pentylenetetrazol (PTZ)."7.68Effects of selective toxic lesions of cholinergic neurons of the laterodorsal tegmental nucleus on experimental seizures. ( Bardgett, ME; Gray, BC; Miller, JW, 1992)
"The specific binding of [3H]hemicholinium-3 ([3H]HCh-3) and high-affinity [3H]choline uptake were measured in rats with status epilepticus induced by lithium and pilocarpine."7.68[3H]hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine. ( Coyle, JT; Saltarelli, MD; Yamada, K, 1991)
"The cerebellar incorporation of labeled choline into phosphatidylcholine (PC) and its hydrosoluble choline-containing precursors has been examined during the course of bicuculline-induced convulsive seizures."7.67Cerebellar metabolism of phosphatidylcholine and its hydrosoluble precursors during bicuculline-induced convulsive seizures. ( Arienti, G; Corazzi, L; Marku, N; Piccinin, GL, 1986)
" A major challenge lies in the lack of knowledge about the bioavailability and pharmacodynamic effects of bioactive compounds in this model organism."5.91Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation. ( Budzyńska, B; Gertsch, J; Kozioł, E; Lee, SM; Morozova, V; Pellegata, D; Skalicka-Woźniak, K; Skiba, A, 2023)
"Evidence suggests that soman-induced convulsions may be associated with postexposure brain neuropathology."5.28Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms. ( Capacio, BR; Koviak, TA; Shih, TM, 1991)
"Compared to nonpregnant women, women with normal pregnancy and preeclampsia had lower levels of the cerebral osmolytes, myo-inositol, choline and creatine (P = 0."3.88Cerebral Osmolytes and Plasma Osmolality in Pregnancy and Preeclampsia: A Proton Magnetic Resonance Spectroscopy Study. ( Bergman, L; Larsson, A; Nelander, M; Sundström-Poromaa, I; Weis, J; Wikström, AK; Wikström, J, 2018)
") of saline (control) or kainic acid to induce seizures and were euthanized 16 days later."3.77Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood. ( Blusztajn, JK; Glenn, MJ; Mellott, TJ; Tognoni, CM; Williams, CL; Wong-Goodrich, SJ, 2011)
"Prenatal choline supplementation can protect rats against cognitive deficits induced by status epilepticus induced by the cholinergic agent pilocarpine [J."3.71Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus. ( Blusztajn, JK; Cermak, JM; Holmes, GL; Liu, Z; Neill, JC; Sarkisian, MR; Stafstrom, CE; Yang, Y, 2002)
"This study determined the effects of bilateral discrete partial lesions of cholinergic neurons of the laterodorsal tegmental nucleus (LDTg) of the pontomesencephalic tegmentum on seizures induced by intravenous pentylenetetrazol (PTZ)."3.68Effects of selective toxic lesions of cholinergic neurons of the laterodorsal tegmental nucleus on experimental seizures. ( Bardgett, ME; Gray, BC; Miller, JW, 1992)
"The specific binding of [3H]hemicholinium-3 ([3H]HCh-3) and high-affinity [3H]choline uptake were measured in rats with status epilepticus induced by lithium and pilocarpine."3.68[3H]hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine. ( Coyle, JT; Saltarelli, MD; Yamada, K, 1991)
"The cerebellar incorporation of labeled choline into phosphatidylcholine (PC) and its hydrosoluble choline-containing precursors has been examined during the course of bicuculline-induced convulsive seizures."3.67Cerebellar metabolism of phosphatidylcholine and its hydrosoluble precursors during bicuculline-induced convulsive seizures. ( Arienti, G; Corazzi, L; Marku, N; Piccinin, GL, 1986)
" Kainic acid (KA), a rigid structural analog of Glu, powerfully reproduces the excitatory neurotoxic (excitotoxic) action of Glu on central neurons and, in addition, causes sustained limbic seizures and a pattern of seizure-linked brain damage in rats that closely resembles that observed in human epilepsy."3.67Excitotoxic mechanisms of epileptic brain damage. ( Collins, RC; Olney, JW; Sloviter, RS, 1986)
"Two female infants with nonketotic hyperglycinemia (NKH) were treated with diazepam for the control of seizures."3.66Nonketotic hyperglycinemia: treatment with diazepam--a competitor for glycine receptors. ( Hughes, JR; Matalon, R; Michals, K; Naidu, S, 1983)
" A major challenge lies in the lack of knowledge about the bioavailability and pharmacodynamic effects of bioactive compounds in this model organism."1.91Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation. ( Budzyńska, B; Gertsch, J; Kozioł, E; Lee, SM; Morozova, V; Pellegata, D; Skalicka-Woźniak, K; Skiba, A, 2023)
"Animals that developed seizures, regardless of the nerve agent, had significantly higher extracellular striatal ACh levels compared to the controls or those animals that did not develop seizures, yet both S and NS groups displayed similar levels of blood AChE inhibition."1.36Changes in extracellular striatal acetylcholine and brain seizure activity following acute exposure to nerve agents in freely moving guinea pigs. ( McDonough, JH; O'Donnell, JC; Shih, TM, 2010)
"Pilomotor seizure (PS) is a rare subtype of simple and complex partial seizures, often related to temporal lobe epilepsy and occasionally linked to alterations of amygdala."1.36Dissociation between neurovegetative signs and subjective symptoms in a case of idiopathic pilomotor seizures. ( Balestrieri, A; Barberini, L; Bortolato, M; Genugu, F; Gioi, G; Marrosu, F; Puligheddu, M, 2010)
"Seizures were analyzed by: number of clinical seizures in 24 h, exact duration of clinical symptoms in 24 h, frequency of interictal epileptiform discharges (IEDs) and ictal activity, duration of ictal activity, and IEDs occurring within 24 h in intensive EEG monitoring."1.341H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG. ( Doelken, M; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Kerling, F; Nimsky, C; Schwarz, M; Stadlbauer, A; Stefan, H, 2007)
"Our results demonstrate effects of seizures on the hippocampi in neocortical epilepsy and the relation between SGTCS and NAA/Cr of the contralateral hippocampus in mTLE."1.33Effect of seizure on hippocampus in mesial temporal lobe epilepsy and neocortical epilepsy: an MRS study. ( Chang, KH; Chung, CK; Kim, DW; Kim, KK; Lee, SK; Song, IC, 2005)
"They presented with congenital microcephaly, severe psychomotor retardation and intractable seizures."1.31Hypomyelination and reversible white matter attenuation in 3-phosphoglycerate dehydrogenase deficiency. ( de Koning, TJ; Jaeken, J; Pineda, M; Poll-The, BT; van der Knaap, MS; Van Maldergem, L, 2000)
"Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging."1.31Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome. ( Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ, 2002)
"Kainic acid (KA)-induced seizures lead to histopathologic changes in rat brain."1.30MRS metabolic markers of seizures and seizure-induced neuronal damage. ( Comair, YG; Lüders, HO; Najm, IM; Ng, TC; Shedid, D; Wang, Y, 1998)
"Choline treatment did not change brain choline content, and was not associated with clinical or radiological improvement."1.30One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. ( Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH, 1998)
"Interestingly, convulsions which were observed in the NMDA-treated rats were almost totally suppressed by bilobalide."1.30Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus. ( Chatterjee, SS; Hilgert, M; Klein, J; Lehr, M; Weichel, O, 1999)
"Evidence suggests that soman-induced convulsions may be associated with postexposure brain neuropathology."1.28Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms. ( Capacio, BR; Koviak, TA; Shih, TM, 1991)
"Choline was found unsuitable, since it induced repetitive firing in the absence of any convulsant agent."1.26Effect of sodium ions on penicillin-induced epileptiform activity in vitro. ( Andersen, P; Hablitz, JJ, 1982)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199020 (40.00)18.7374
1990's9 (18.00)18.2507
2000's12 (24.00)29.6817
2010's7 (14.00)24.3611
2020's2 (4.00)2.80

Authors

AuthorsStudies
Skiba, A1
Pellegata, D1
Morozova, V1
Kozioł, E1
Budzyńska, B1
Lee, SM1
Gertsch, J1
Skalicka-Woźniak, K1
Simani, L1
Raminfard, S1
Asadollahi, M1
Roozbeh, M1
Ryan, F1
Rostami, M1
Nelander, M1
Wikström, AK1
Weis, J1
Bergman, L1
Larsson, A1
Sundström-Poromaa, I1
Wikström, J1
Surina, NM1
Ashapkin, VV1
Merzalov, IB1
Perepelkina, OV1
Fedotova, IB1
Pavlova, GV1
Poletaeva, II1
Fadaie, F1
Mobarakeh, NM1
Fesharaki, SS1
Harirchian, MH1
Kharazi, HH1
Rad, HS1
Habibabadi, JM1
Simister, RJ1
McLean, MA1
Salmenpera, TM1
Barker, GJ1
Duncan, JS1
O'Donnell, JC1
McDonough, JH1
Shih, TM2
HYDE, J1
BECKETT, S1
GELLHORN, E1
TOBIAS, JM1
LIPTON, MA1
LEPINAT, AA1
Puligheddu, M1
Bortolato, M1
Barberini, L1
Genugu, F1
Gioi, G1
Balestrieri, A1
Marrosu, F1
Wong-Goodrich, SJ1
Tognoni, CM1
Mellott, TJ1
Glenn, MJ1
Blusztajn, JK2
Williams, CL1
Lavrnic, S1
Macvanski, M1
Ristic-Balos, D1
Gavrilov, M1
Damjanovic, D1
Gavrilovic, S1
Milicevic, M1
Skender-Gazibara, M1
Stosic-Opincal, T1
Hájek, M1
Dezortová, M1
Liscák, R1
Vymazal, J1
Vladyka, V1
ZEIMAL, EV1
ZEIMAL', EV1
Bassuk, AG1
Joshi, A1
Burton, BK1
Larsen, MB1
Burrowes, DM1
Stack, C1
Celik, T1
Kayir, H1
Ceyhan, M1
Demirtaş, S1
Coşar, A1
Uzbay, IT1
Brissaud, O1
Chateil, JF1
Bordessoules, M1
Brun, M1
Lee, SK1
Kim, DW1
Kim, KK1
Chung, CK1
Song, IC1
Chang, KH1
Hammen, T1
Schwarz, M1
Doelken, M1
Kerling, F1
Engelhorn, T1
Stadlbauer, A1
Ganslandt, O1
Nimsky, C1
Doerfler, A1
Stefan, H1
Riederer, F1
Bittsanský, M1
Lehner-Baumgartner, E1
Baumgartner, C1
Mlynárik, V1
Gruber, S1
Moser, E1
Kaya, M1
Serles, W1
Hartmann, J1
Kiewert, C1
Duysen, EG1
Lockridge, O1
Klein, J2
Dietzel, I1
Heinemann, U1
Hofmeier, G1
Lux, HD1
Hablitz, JJ1
Andersen, P1
Matalon, R1
Naidu, S1
Hughes, JR1
Michals, K1
McCann, K1
Cain, DP1
Philbrick, DJ1
Dasheiff, RM1
Byrne, MC1
Patrone, V1
McNamara, JO1
Abood, LG1
Saraswati, M1
Lerner-Marmarosh, N1
Hashmi, M1
Najm, IM2
Wang, Y2
Hong, SC1
Lüders, HO2
Ng, TC2
Comair, YG2
Shedid, D1
Van Hove, JL1
Lazeyras, F1
Zeisel, SH1
Bottiglieri, T1
Hyland, K1
Charles, HC1
Gray, L1
Jaeken, J2
Kahler, SG1
Weichel, O1
Hilgert, M1
Chatterjee, SS1
Lehr, M1
de Koning, TJ1
Pineda, M1
Van Maldergem, L1
Poll-The, BT1
van der Knaap, MS1
Holmes, GL1
Yang, Y1
Liu, Z1
Cermak, JM1
Sarkisian, MR1
Stafstrom, CE1
Neill, JC1
Eichler, FS1
Wang, P1
Wityk, RJ1
Beauchamp, NJ1
Barker, PB1
Bondy, SC1
Tepper, JM1
Bettis, DB1
Miller, JW1
Gray, BC1
Bardgett, ME1
Yamada, K1
Saltarelli, MD1
Coyle, JT1
Koviak, TA1
Capacio, BR1
Zis, AP1
Nomikos, GG1
Damsma, G1
Fibiger, HC1
Corazzi, L1
Piccinin, GL1
Marku, N1
Arienti, G1
Olney, JW1
Collins, RC1
Sloviter, RS1
Flynn, CJ1
Wecker, L1
Karlsson, A1
Fonnum, F1
Malthe-Sorenssen, D1
Storm-Mathisen, J1
Emmrich, P1
Jüngst, BK1
Dick, W1
Saelens, JK1
Rosenblum, I1
Ecobichon, DJ1
Comeau, AM1
Sytiniskiĭ, IA1
Slater, P1
Ashida, H1
Takeuchi, N1
Mori, A1
Jinnai, D1

Reviews

1 review available for choline and Seizures

ArticleYear
[Clinical use of gamma-aminobutyric acid derivatives in experimental and clinical psychiatry and neurology (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1971, Volume: 71, Issue:2

    Topics: Aminobutyrates; Animals; Choline; Epilepsy; Humans; Hydroxybutyrates; Hypertension; Hypoxia; Mental

1971

Other Studies

49 other studies available for choline and Seizures

ArticleYear
Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation.
    Cells, 2023, 06-04, Volume: 12, Issue:11

    Topics: Acetylcholine; Animals; Anticonvulsants; Choline; Humans; Pentylenetetrazole; Seizures; Serotonin; T

2023
Neurochemicals of limbic system and thalamofrontal cortical network: Are they different between patients with idiopathic generalized epilepsy and psychogenic nonepileptic seizure?
    Epilepsy & behavior : E&B, 2020, Volume: 112

    Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Generalized; Humans; Magnetic Resonance Spectrosc

2020
Cerebral Osmolytes and Plasma Osmolality in Pregnancy and Preeclampsia: A Proton Magnetic Resonance Spectroscopy Study.
    American journal of hypertension, 2018, 06-11, Volume: 31, Issue:7

    Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Cerebrovascular Circulation; Choline; Creatine;

2018
Audiogenic seizure proneness after methyl-enriched diet in ontogeny.
    Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2014, Volume: 454

    Topics: Animals; Betaine; Choline; Diet; DNA Methylation; Epilepsy, Reflex; Female; Methionine; Pregnancy; P

2014
1H-MRS metabolite's ratios show temporal alternation in temporal lobe seizure: Comparison between interictal and postictal phases.
    Epilepsy research, 2016, Volume: 128

    Topics: Adult; Aspartic Acid; Choline; Creatinine; Drug Resistant Epilepsy; Electroencephalography; Epilepsy

2016
The effect of epileptic seizures on proton MRS visible neurochemical concentrations.
    Epilepsy research, 2008, Volume: 81, Issue:1

    Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Data Interpretation, Statistical; Dipeptid

2008
Changes in extracellular striatal acetylcholine and brain seizure activity following acute exposure to nerve agents in freely moving guinea pigs.
    Toxicology mechanisms and methods, 2010, Volume: 20, Issue:3

    Topics: Acetylcholine; Animals; Brain; Chemical Warfare Agents; Choline; Cholinesterase Inhibitors; Corpus S

2010
Acetylcholine, cholinesterase, eserine and convulsions.
    Federation proceedings, 1947, Volume: 6, Issue:1 Pt 2

    Topics: Acetylcholine; Choline; Cholinesterases; Physostigmine; Seizures

1947
Effect of anesthetics and convulsants on brain acetylcholine content.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1946, Volume: 61

    Topics: Acetylcholine; Anesthesia; Anesthetics; Brain; Brain Chemistry; Choline; Convulsants; Humans; Seizur

1946
Dissociation between neurovegetative signs and subjective symptoms in a case of idiopathic pilomotor seizures.
    Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2010, Volume: 23, Issue:4

    Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Electroencephalography; Epilepsy, Complex

2010
Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood.
    Brain research, 2011, Sep-21, Volume: 1413

    Topics: Age Factors; Animals; Choline; Choline Deficiency; Disease Susceptibility; Female; Hippocampus; Kain

2011
Papillary glioneuronal tumor: unexplored entity.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:4

    Topics: Adult; Brain Neoplasms; Choline; Creatinine; Diffusion Magnetic Resonance Imaging; Female; Glioma; H

2012
1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
    European radiology, 2003, Volume: 13, Issue:5

    Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Fo

2003
[ON THE CHARACTERISTICS OF CENTRAL CHOLINE RECEPTORS SIMULATED BY NICOTINE].
    Doklady Akademii nauk SSSR, 1964, Jul-01, Volume: 157

    Topics: Animals; Cerebral Ventricles; Choline; Hexamethonium Compounds; Mice; Muscle Relaxants, Central; Nic

1964
[Prevention of arecolinic and nicotinic convulsions in rabbits with cholinolytic substances].
    Biulleten' eksperimental'noi biologii i meditsiny, 1955, Volume: 39, Issue:1

    Topics: Animals; Anticonvulsants; Choline; Cholinergic Antagonists; Lagomorpha; Rabbits; Seizures

1955
Alexander disease with serial MRS and a new mutation in the glial fibrillary acidic protein gene.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Acidosis, Respiratory; Alexander Disease; Basal Ganglia; Choline; Creatine; Disease Progression; DNA

2003
CPP and amlodipine alter the decrease in basal acetylcholine and choline release by audiogenic stimulus in hippocampus of ethanol-withdrawn rats in vivo.
    Brain research bulletin, 2004, Sep-30, Volume: 64, Issue:3

    Topics: Acetylcholine; Acoustic Stimulation; Alcohol-Induced Disorders, Nervous System; Amlodipine; Animals;

2004
Chemical shift imaging and localised magnetic resonance spectroscopy in full-term asphyxiated neonates.
    Pediatric radiology, 2005, Volume: 35, Issue:10

    Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Brain; Choline; Creatine; Electroencephalography; F

2005
Effect of seizure on hippocampus in mesial temporal lobe epilepsy and neocortical epilepsy: an MRS study.
    Neuroradiology, 2005, Volume: 47, Issue:12

    Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Epilepsy, Temporal Lobe; Female; Hippocampus; H

2005
1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG.
    Epilepsia, 2007, Volume: 48, Issue:2

    Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Choline; Creatine; Dipeptides; Electroencephalograp

2007
Decrease of NAA with aging outside the seizure focus in mesial temporal lobe epilepsy--a proton-MRS study at 3 Tesla.
    Brain research, 2007, Nov-07, Volume: 1179

    Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Drug Resistance; Epilepsy, Temporal Lobe

2007
Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice.
    Neurochemistry international, 2008, Volume: 52, Issue:6

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Choline; Cholinergic Antagonists; Down-Regulation; Ext

2008
Transient changes in the size of the extracellular space in the sensorimotor cortex of cats in relation to stimulus-induced changes in potassium concentration.
    Experimental brain research, 1980, Volume: 40, Issue:4

    Topics: Animals; Cats; Choline; Electric Stimulation; Extracellular Space; Neurons; Potassium; Seizures; Som

1980
Effect of sodium ions on penicillin-induced epileptiform activity in vitro.
    Experimental brain research, 1982, Volume: 47, Issue:1

    Topics: Animals; Choline; Culture Techniques; Evoked Potentials; Guinea Pigs; Hippocampus; Penicillins; Seiz

1982
Nonketotic hyperglycinemia: treatment with diazepam--a competitor for glycine receptors.
    Pediatrics, 1983, Volume: 71, Issue:4

    Topics: Binding, Competitive; Choline; Diazepam; Electroencephalography; Female; Folic Acid; Glycine; Humans

1983
Facilitation of kindled seizures in rats fed choline-supplemented diets.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1983, Volume: 10, Issue:1

    Topics: Amygdala; Animals; Choline; Diet; Electric Stimulation; Kindling, Neurologic; Male; Rats; Seizures

1983
Biochemical evidence of decreased muscarinic cholinergic neuronal communication following amygdala-kindled seizures.
    Brain research, 1981, Feb-09, Volume: 206, Issue:1

    Topics: Acetylcholinesterase; Amygdala; Animals; Biological Transport, Active; Choline; Male; Neurons; Penty

1981
Affinity ligands and related agents for brain muscarinic and nicotinic cholinergic receptors.
    Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10

    Topics: Affinity Labels; Animals; Brain; Carbachol; Choline; Kinetics; Ligands; Mice; Naloxone; Nicotine; Ox

1993
Temporal changes in proton MRS metabolites after kainic acid-induced seizures in rat brain.
    Epilepsia, 1997, Volume: 38, Issue:1

    Topics: Animals; Aspartic Acid; Brain; Cell Count; Choline; Creatinine; Dipeptides; Disease Models, Animal;

1997
MRS metabolic markers of seizures and seizure-induced neuronal damage.
    Epilepsia, 1998, Volume: 39, Issue:3

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Cell Count; Choline; Creatine; Cycloheximide; Hippocampus

1998
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
    Journal of inherited metabolic disease, 1998, Volume: 21, Issue:8

    Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine;

1998
Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:6

    Topics: Animals; Cells, Cultured; Choline; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Enzy

1999
Hypomyelination and reversible white matter attenuation in 3-phosphoglycerate dehydrogenase deficiency.
    Neuropediatrics, 2000, Volume: 31, Issue:6

    Topics: Amino Acids; Carbohydrate Dehydrogenases; Cerebral Cortex; Child; Child, Preschool; Choline; Demyeli

2000
Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus.
    Epilepsy research, 2002, Volume: 48, Issue:1-2

    Topics: Animals; Choline; Choline Deficiency; Dietary Supplements; Female; Hippocampus; Male; Maze Learning;

2002
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:5

    Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnet

2002
Seizure proneness and neurotransmitter uptake.
    Neurochemical research, 1979, Volume: 4, Issue:6

    Topics: Animals; Biological Transport; Choline; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glycine; Mese

1979
Effects of selective toxic lesions of cholinergic neurons of the laterodorsal tegmental nucleus on experimental seizures.
    Brain research, 1992, May-01, Volume: 579, Issue:1

    Topics: Animals; Aziridines; Choline; Cholinergic Fibers; Female; Histocytochemistry; NADPH Dehydrogenase; P

1992
[3H]hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine.
    European journal of pharmacology, 1991, Apr-03, Volume: 195, Issue:3

    Topics: Acetylcholine; Animals; Cerebral Cortex; Chlorides; Choline; Hemicholinium 3; Hippocampus; Kinetics;

1991
Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms.
    Neuroscience and biobehavioral reviews, 1991,Fall, Volume: 15, Issue:3

    Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidotes; Atropine; Brain Chemistry;

1991
In vivo neurochemical effects of electroconvulsive shock studied by microdialysis in the rat striatum.
    Psychopharmacology, 1991, Volume: 103, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Brain Chemistry; Choline; Convulsants; Corpu

1991
Cerebellar metabolism of phosphatidylcholine and its hydrosoluble precursors during bicuculline-induced convulsive seizures.
    Neurochemical research, 1986, Volume: 11, Issue:3

    Topics: Animals; Bicuculline; Cerebellum; Choline; Female; Phosphatidylcholines; Phosphorylcholine; Rats; Ra

1986
Excitotoxic mechanisms of epileptic brain damage.
    Advances in neurology, 1986, Volume: 44

    Topics: Administration, Topical; Amygdala; Animals; Axons; Biomechanical Phenomena; Brain; Choline; Cholines

1986
Concomitant increases in the levels of choline and free fatty acids in rat brain: evidence supporting the seizure-induced hydrolysis of phosphatidylcholine.
    Journal of neurochemistry, 1987, Volume: 48, Issue:4

    Topics: Animals; Brain; Choline; Diazepam; Fatty Acids, Nonesterified; Hydrolysis; Male; Phosphatidylcholine

1987
Effect of the convulsive agent 3-mercaptopropionic acid on the levels of GABA, other amino acids and glutamate decarboxylase in different regions of the rat brain.
    Biochemical pharmacology, 1974, Nov-01, Volume: 23, Issue:21

    Topics: Acetyltransferases; Amino Acids; Aminobutyrates; Animals; Brain; Brain Chemistry; Carboxy-Lyases; Ce

1974
[Possible applications of complete relaxation in pediatric intensive care].
    Der Anaesthesist, 1971, Volume: 20, Issue:6

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Anticonvulsants; Carbamates; Child; Child, Preschool;

1971
The anticonvulsant activity of triethylcholine in cats.
    Experimental neurology, 1966, Volume: 14, Issue:4

    Topics: Animals; Anticonvulsants; Cats; Choline; Female; Male; Pentylenetetrazole; Phenobarbital; Seizures

1966
Genetic polymorphism of plasma carboxylesterases in the rabbit: correlation with pharmacologic and toxicologic effects.
    Toxicology and applied pharmacology, 1974, Volume: 27, Issue:1

    Topics: Acetates; Animals; Atropine; Behavior, Animal; Benzoates; Choline; Cholinesterases; Electrophoresis;

1974
Catatonia and convulsive activity following intraventricular injections of quaternary ammonium compounds in the rat.
    The Journal of physiology, 1968, Volume: 197, Issue:1

    Topics: Animals; Antimetabolites; Catatonia; Cerebral Ventricles; Choline; Humans; Injections; Quaternary Am

1968
Anti-convulsive action of gamma-aminobutyryl choline.
    Nature, 1965, May-01, Volume: 206, Issue:983

    Topics: Animals; Anticonvulsants; Blood Pressure; Blood-Brain Barrier; Body Temperature; Choline; Dogs; Elec

1965