moclobemide has been researched along with Seizures in 4 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we examined the effect of both acute and chronic treatment with moclobemide on seizures and the action of first-generation antiepileptic drugs: valproate, carbamazepine, phenobarbital and phenytoin." | 4.02 | Acute and chronic treatment with moclobemide, a reversible MAO-inhibitor, potentiates the antielectroshock activity of conventional antiepileptic drugs in mice. ( Banach, M; Borowicz-Reutt, KK, 2021) |
| "Effects of chronic moclobemide administration on ethanol consumption, blood ethanol level, motor coordination and seizures induced by an audiogenic stimulus during ethanol withdrawal syndrome have been investigated in chronically ethanol intoxicated rats." | 3.69 | Investigation of the effects of moclobemide in chronic ethanol feeding rats. ( Ayhan, IH; Celik, T; Sever, B; Uzbay, IT, 1995) |
| "The reversible MAO-A inhibitor moclobemide (5 mg/kg) was shown to prevent seizures in rats during exposure to toxic oxygen (6 ata)." | 3.67 | [Effect of benzamide derivatives on convulsions induced by the toxic action of oxygen in rats]. ( Demurov, EA; Gol'dina, OA; Koloskov, IuB; Tepliakov, VG; Zagorevskiĭ, VA, 1987) |
| " While clinical aspects will be presented in a subsequent review, this article focuses primarily on moclobemide's evolution, pharmacodynamic and pharmacokinetic properties." | 2.41 | Moclobemide: evolution, pharmacodynamic, and pharmacokinetic properties. ( Bonnet, U, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borowicz-Reutt, KK | 1 |
| Banach, M | 1 |
| Bonnet, U | 1 |
| Uzbay, IT | 1 |
| Sever, B | 1 |
| Celik, T | 1 |
| Ayhan, IH | 1 |
| Gol'dina, OA | 1 |
| Tepliakov, VG | 1 |
| Demurov, EA | 1 |
| Koloskov, IuB | 1 |
| Zagorevskiĭ, VA | 1 |
1 review available for moclobemide and Seizures
| Article | Year |
|---|---|
Moclobemide: evolution, pharmacodynamic, and pharmacokinetic properties.
Topics: Animals; Antidepressive Agents; Anxiety; Cognition Disorders; Depression; Disease Models, Animal; Dr | 2002 |
3 other studies available for moclobemide and Seizures
| Article | Year |
|---|---|
Acute and chronic treatment with moclobemide, a reversible MAO-inhibitor, potentiates the antielectroshock activity of conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, | 2021 |
Investigation of the effects of moclobemide in chronic ethanol feeding rats.
Topics: Alcohol Drinking; Animals; Benzamides; Body Weight; Central Nervous System Depressants; Ethanol; Mal | 1995 |
[Effect of benzamide derivatives on convulsions induced by the toxic action of oxygen in rats].
Topics: Animals; Anticonvulsants; Benzamides; Brain; Clorgyline; Drug Evaluation, Preclinical; Heart; Male; | 1987 |