Page last updated: 2024-10-23

azathioprine and Seizures

azathioprine has been researched along with Seizures in 19 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Severe side effects, specially infections, are uncommon but clinically relevant with several deaths reported."2.43Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review. ( García-López, S; Gomollón-García, F; Pérez-Gisbert, J, 2005)
"Hashimoto's encephalopathy (HE) is a rare neurological disorder."1.40Hashimoto's encephalopathy: South Korean experiences. ( Kang, K; Kim, BK; Kim, J; Kwon, O; Lee, JJ; Park, JM; Shin, H, 2014)
"Mixed connective tissue disorder (MCTD) with predominant polymyositis and neuropsychiatric manifestations was diagnosed as the patient had anti-RNP positive with significantly raised muscle enzymes."1.40Depression and seizures as the main neuropsychiatric manifestation of mixed connective tissue disorder. ( Kiani, IG; Qureshi, SH; Shah, F, 2014)
"We report a case of Susac's syndrome in which the patient improved immediately after tumour necrosis factor (TNF) inhibition with the monoclonal antibody, infliximab."1.37Tumour necrosis factor (TNF) inhibitor therapy in Susac's syndrome. ( Barnett, MH; Fulham, MJ; Garsia, RJ; Halmagyi, GM; Hardy, TA; Harrisberg, B; Lewis, SJ, 2011)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's2 (10.53)18.2507
2000's5 (26.32)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, J1
Shin, H1
Kang, K1
Kwon, O1
Park, JM1
Kim, BK1
Lee, JJ1
Kiani, IG1
Qureshi, SH1
Shah, F1
Geyer, M1
Fairchild, J1
Moore, D1
Moore, L1
Henning, P1
Tham, E1
Zamvar, V1
Sugarman, ID1
Tawfik, RF1
Macmullen-Price, J1
Puntis, JW1
Annapandian, VM1
John, GT1
Mathew, BS1
Fleming, DH1
Hardy, TA1
Garsia, RJ1
Halmagyi, GM1
Lewis, SJ1
Harrisberg, B1
Fulham, MJ1
Barnett, MH1
Al Riyami, AZ1
Jacobson, K1
Ford, J1
Dalal, BI1
Tsuji, RK1
Bittencourt, AG1
Arai, MH1
Santiago Gebrim, EM1
Taylor, I1
García-López, S1
Gomollón-García, F1
Pérez-Gisbert, J1
Everett, CM1
Graves, TD1
Lad, S1
Jäger, HR1
Thom, M1
Isenberg, DA1
Hanna, MG1
Shihab, F1
Barry, JM1
Bennett, WM1
Meyer, MM1
Norman, DJ1
Pearson, ER1
D'Souza, RJ1
Hamilton-Wood, C1
Nicholls, AJ1
Beaman, M1
Bennahum, DA1
Messner, RP1
Tejani, A1
Butt, KM1
Khawar, MR1
Hong, JH1
Fusi, M1
Pomrantz, A1
Schneck, SA1
Cho, ES1
Connolly, E1
Porro, RS1
Carlisle, H1
Spector, RG1
Brass, H1

Reviews

2 reviews available for azathioprine and Seizures

ArticleYear
Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review.
    Gastroenterologia y hepatologia, 2005, Volume: 28, Issue:10

    Topics: Administration, Oral; Adrenal Cortex Hormones; Azathioprine; Clinical Trials as Topic; Colitis, Ulce

2005
Recent observations on central nervous system lupus erythematosus.
    Seminars in arthritis and rheumatism, 1975, Volume: 4, Issue:3

    Topics: Animals; Antibodies, Viral; Autoantibodies; Azathioprine; Central Nervous System Diseases; Child; Co

1975

Other Studies

17 other studies available for azathioprine and Seizures

ArticleYear
Hashimoto's encephalopathy: South Korean experiences.
    Acta neurologica Belgica, 2014, Volume: 114, Issue:3

    Topics: Aged; Aged, 80 and over; Antimetabolites; Azathioprine; Brain; Brain Diseases; Electroencephalograph

2014
Depression and seizures as the main neuropsychiatric manifestation of mixed connective tissue disorder.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2014, Volume: 24 Suppl 2

    Topics: Adult; Antibodies, Antinuclear; Anticonvulsants; Antidepressive Agents, Second-Generation; Azathiopr

2014
Recalcitrant hypocalcaemia in autoimmune enteropathy.
    Pediatrics, 2014, Volume: 134, Issue:6

    Topics: Adolescent; Azathioprine; Biopsy; Calcitriol; Calcium Citrate; Child, Preschool; Cyclosporine; Drug

2014
Posterior reversible encephalopathy syndrome following infliximab infusion.
    Journal of pediatric gastroenterology and nutrition, 2009, Volume: 48, Issue:1

    Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Brain Di

2009
Pharmacokinetic interaction between sodium valproate and mycophenolate in renal allograft recipients.
    Transplantation, 2009, Nov-15, Volume: 88, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Azathioprine; Female; Glucocorticoids; Graft R

2009
Tumour necrosis factor (TNF) inhibitor therapy in Susac's syndrome.
    Journal of the neurological sciences, 2011, Mar-15, Volume: 302, Issue:1-2

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Brain; Cognition Disorders; Cyclopho

2011
Transient appearance of GPI-deficient population in a patient with azathioprine-associated bone marrow aplasia.
    Annals of hematology, 2012, Volume: 91, Issue:10

    Topics: Anemia, Aplastic; Azathioprine; Child; Glycosylphosphatidylinositols; Hemoglobinuria, Paroxysmal; Hu

2012
Cochleovestibular nerve involvement in multifocal fibrosclerosis.
    The Journal of laryngology and otology, 2012, Volume: 126, Issue:9

    Topics: Azathioprine; Biopsy; Diagnosis, Differential; Disease Progression; Female; Glucocorticoids; Humans;

2012
Cavernous hemangioma. Reversible posterior leukoencephalopathy syndrome.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2003, Volume: 10, Issue:6

    Topics: Adult; Azathioprine; Diabetes Mellitus, Type 1; Diffusion Magnetic Resonance Imaging; Female; Hemang

2003
Aggressive CNS lupus vasculitis in the absence of systemic disease activity.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:1

    Topics: Anticonvulsants; Autoantibodies; Azathioprine; Brain; Cyclophosphamide; Electroencephalography; Fema

2008
Cytokine-related encephalopathy induced by OKT3: incidence and predisposing factors.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 1

    Topics: Azathioprine; Brain Diseases; Coma; Confusion; Cyclosporine; Cytokines; Female; Follow-Up Studies; H

1993
Hypertensive encephalopathy and nephrotic syndrome: a possible link?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:7

    Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Azathioprine; Brain Diseases; Calcium Channel Blo

1999
Cyclosporine experience in renal transplantation in children.
    The Mount Sinai journal of medicine, New York, 1987, Volume: 54, Issue:6

    Topics: Adolescent; Anemia; Azathioprine; Child; Creatinine; Cyclosporins; Female; Gingival Hyperplasia; Gra

1987
Neurology and neuropathology of immunosuppressive therapy and acquired immunological deficiency.
    Research publications - Association for Research in Nervous and Mental Disease, 1971, Volume: 49

    Topics: Adolescent; Adult; Agammaglobulinemia; Aspergillus; Azathioprine; Brain; Brain Diseases; Candida; Ce

1971
Primary reticulum cell sarcoma of the brain in a renal transplantation recipient.
    Journal of neurosurgery, 1974, Volume: 41, Issue:2

    Topics: Abscess; Adult; Azathioprine; Brain Neoplasms; Chronic Disease; Epididymitis; Frontal Lobe; Glomerul

1974
The effect of anti-metabolites on leptazol induced fits in rats.
    Clinical science, 1971, Volume: 40, Issue:6

    Topics: Animals; Antimetabolites; Azathioprine; Brain; Cytarabine; Daunorubicin; Fluorouracil; Folic Acid; F

1971
[Therapeutic possibilities in chronic glomerulonephritis].
    Munchener medizinische Wochenschrift (1950), 1969, Aug-29, Volume: 111, Issue:35

    Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Chronic Disease; Glomerulonephritis; Humans; Immunosu

1969