succinic acid has been researched along with Seizures in 5 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study explored the role of succinate accumulation in the oxidative stress and iron accumulation in both pentylenetetrazol (PTZ)-induced epileptogenesis and kainic acid (KA)-induced status epilepticus (SE)." | 4.02 | Succinate accumulation contributes to oxidative stress and iron accumulation in pentylenetetrazol-induced epileptogenesis and kainic acid-induced seizure. ( Cheng, Y; Cui, Y; Huang, W; Li, S; Liu, W; Sun, H; Xin, W; Zhang, M; Zhang, Y; Zhu, W, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Cui, Y | 1 |
| Cheng, Y | 1 |
| Zhu, W | 1 |
| Zhang, M | 1 |
| Li, S | 1 |
| Liu, W | 1 |
| Xin, W | 1 |
| Huang, W | 1 |
| Sun, H | 1 |
| Zhang, J | 1 |
| Chen, J | 1 |
| Tan, XL | 1 |
| Ren, YG | 1 |
| Du, YP | 1 |
| Zhang, YP | 1 |
| Royes, LF | 1 |
| Fighera, MR | 1 |
| Furian, AF | 1 |
| Oliveira, MS | 1 |
| da Silva, LG | 1 |
| Malfatti, CR | 1 |
| Schneider, PH | 1 |
| Braga, AL | 1 |
| Wajner, M | 1 |
| Mello, CF | 2 |
| KOHAN, AB | 1 |
| Roehrs, C | 1 |
| Garrido-Sanabria, ER | 1 |
| Da Silva, AC | 1 |
| Faria, LC | 1 |
| Sinhorin, VD | 1 |
| Marques, RH | 1 |
| Priel, MR | 1 |
| Rubin, MA | 1 |
| Cavalheiro, EA | 1 |
5 other studies available for succinic acid and Seizures
| Article | Year |
|---|---|
Succinate accumulation contributes to oxidative stress and iron accumulation in pentylenetetrazol-induced epileptogenesis and kainic acid-induced seizure.
Topics: Animals; Cerebral Cortex; Hippocampus; Iron; Kainic Acid; Male; Malonates; Oxidative Stress; Pentyle | 2021 |
[Protective effect of succinic acid on cerebellar Purkinje cells of neonatal rats with convulsion].
Topics: Action Potentials; Animals; Animals, Newborn; Cytoprotection; Excitatory Postsynaptic Potentials; Pu | 2016 |
Creatine protects against the convulsive behavior and lactate production elicited by the intrastriatal injection of methylmalonate.
Topics: Animals; Behavior, Animal; Corpus Striatum; Creatine; Disease Models, Animal; Dizocilpine Maleate; D | 2003 |
[New results obtained in the succinic acid therapy of convulsive cough].
Topics: Cough; Seizures; Succinates; Succinic Acid; Whooping Cough | 1954 |
Succinate increases neuronal post-synaptic excitatory potentials in vitro and induces convulsive behavior through N-methyl-d-aspartate-mediated mechanisms.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; E | 2004 |