erythrosine has been researched along with Seizures in 45 studies
Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although caffeine supplementation has a beneficial effect on people with neurological disorders, its implications for oxidative damage related to seizures are not well documented." | 7.79 | Antioxidant activity elicited by low dose of caffeine attenuates pentylenetetrazol-induced seizures and oxidative damage in rats. ( Castro, M; Fighera, MR; Gerbatin, RR; Mota, BC; Rodrigues, FS; Royes, LF; Souza, MA, 2013) |
| "The present study has examined the anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine ((S)-3,4-DCPG), a highly selective agonist for subtype 8 of group III metabotropic glutamate receptors (mGluRs), against seizures induced in immature 12-day-old rats by bilateral icv infusion of DL-homocysteic acid (DL-HCA, 600 nmol/side)." | 7.74 | Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid. ( Druga, R; Folbergrová, J; Haugvicová, R; Mares, P; Otáhal, J, 2008) |
| "The present study has examined the anticonvulsant and neuroprotective effect of group II metabotropic glutamate receptor (mGluR) agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC) in the model of seizures induced in immature 12-day-old rats by bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA, 600 nmol/side)." | 7.73 | Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate. ( Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J, 2005) |
| " Pilocarpine-induced status epilepticus (SE) was chosen as a model to generate chronic epileptic animals." | 7.73 | Septal GABAergic neurons are selectively vulnerable to pilocarpine-induced status epilepticus and chronic spontaneous seizures. ( Banuelos, C; Castañeda, MT; Colom, LV; Garrido Sanabria, ER; Hernandez, S; Perez-Cordova, MG, 2006) |
| "The occurrence of recurrent, unprovoked seizures is the hallmark of human epilepsy." | 5.43 | Eight Flurothyl-Induced Generalized Seizures Lead to the Rapid Evolution of Spontaneous Seizures in Mice: A Model of Epileptogenesis with Seizure Remission. ( Beyer, BS; Ferland, RJ; Herron, BJ; Kadiyala, SB; Nalwalk, JW; Papandrea, D; Yannix, JQ, 2016) |
| "Control of brain seizures after exposure to nerve agents is imperative for the prevention of brain damage and death." | 5.39 | Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administration. ( Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Green, CE; Qashu, F; Swezey, R; Yang, C, 2013) |
| "Epileptic seizures cause severe and long-lasting events on the architecture of the brain, including neuronal cell death, accompanied neurogenesis, reactive gliosis, and mossy fiber sprouting." | 5.33 | Tonic-clonic seizures induce division of neuronal progenitor cells with concomitant changes in expression of neurotrophic factors in the brain of pilocarpine-treated mice. ( Hagihara, H; Hara, M; Nakagawa, Y; Nakano, K; Sawada, M; Tsunekawa, K, 2005) |
| " Using the kainic acid model of status epilepticus, we have studied the effects of repetitive neonatal episodes of status epilepticus on the expression of cation chloride cotransporter KCC2 in the neonatal hippocampus." | 4.84 | Developmental patterns in the regulation of chloride homeostasis and GABA(A) receptor signaling by seizures. ( Galanopoulou, AS, 2007) |
| " In this study, we ablated the hippocampal neurogenesis by methylazoxymethanol acetate (MAM) treatment both before and after pilocarpine induced status epilepticus (SE)." | 3.85 | Reduced abnormal integration of adult-generated granule cells does not attenuate spontaneous recurrent seizures in mice. ( Feng, GF; Hu, M; Liu, JX; Liu, Y; Yuan, B; Zhu, K, 2017) |
| "Although caffeine supplementation has a beneficial effect on people with neurological disorders, its implications for oxidative damage related to seizures are not well documented." | 3.79 | Antioxidant activity elicited by low dose of caffeine attenuates pentylenetetrazol-induced seizures and oxidative damage in rats. ( Castro, M; Fighera, MR; Gerbatin, RR; Mota, BC; Rodrigues, FS; Royes, LF; Souza, MA, 2013) |
| " Proneurotrophins, which are potent apoptosis-inducing ligands for p75(NTR), were increased in the hippocampus, particularly in astrocytes, by pilocarpine-induced seizures; and infusion of anti-pro-NGF dramatically attenuated neuronal loss after seizures." | 3.74 | Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. ( Carter, BD; Cragnolini, A; Friedman, WJ; Hempstead, BL; Kenchappa, RS; Light, M; Trotter, C; Volosin, M, 2008) |
| "The present study has examined the anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine ((S)-3,4-DCPG), a highly selective agonist for subtype 8 of group III metabotropic glutamate receptors (mGluRs), against seizures induced in immature 12-day-old rats by bilateral icv infusion of DL-homocysteic acid (DL-HCA, 600 nmol/side)." | 3.74 | Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid. ( Druga, R; Folbergrová, J; Haugvicová, R; Mares, P; Otáhal, J, 2008) |
| "The present study has examined the anticonvulsant and neuroprotective effect of group II metabotropic glutamate receptor (mGluR) agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC) in the model of seizures induced in immature 12-day-old rats by bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA, 600 nmol/side)." | 3.73 | Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate. ( Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J, 2005) |
| " Pilocarpine-induced status epilepticus (SE) was chosen as a model to generate chronic epileptic animals." | 3.73 | Septal GABAergic neurons are selectively vulnerable to pilocarpine-induced status epilepticus and chronic spontaneous seizures. ( Banuelos, C; Castañeda, MT; Colom, LV; Garrido Sanabria, ER; Hernandez, S; Perez-Cordova, MG, 2006) |
| "We assessed inbred, outbred and hybrid mouse strains for susceptibility to seizures and neurodegeneration induced by systemic administration of kainic acid (KA)." | 3.73 | Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains. ( McLin, JP; Steward, O, 2006) |
| "Tonic-clonic seizures followed intravenous fluorescein injection for fundus angiography in a 47-year-old male." | 3.67 | Convulsion following intravenous fluorescein angiography. ( Kelly, SP; Leach, FN; MacDermott, NJ; Saunders, DC, 1989) |
| "Seizures were monitored in conscious animals for 8h via chronically implanted electroencephalography (EEG) electrodes in the hippocampus and motor cortex and time-synced video." | 1.48 | Inhibition of blood-brain barrier efflux transporters promotes seizure in pregnant rats: Role of circulating factors. ( Cipolla, MJ; Hammer, ES; Holmes, GL; Johnson, AC; Sakkaki, S; Tremble, SM, 2018) |
| "Luteolin treatment reduced the KA-induced seizure score and elevations of glutamate levels in the hippocampus." | 1.43 | Luteolin protects the hippocampus against neuron impairments induced by kainic acid in rats. ( Lin, TY; Lu, CW; Wang, SJ, 2016) |
| "The occurrence of recurrent, unprovoked seizures is the hallmark of human epilepsy." | 1.43 | Eight Flurothyl-Induced Generalized Seizures Lead to the Rapid Evolution of Spontaneous Seizures in Mice: A Model of Epileptogenesis with Seizure Remission. ( Beyer, BS; Ferland, RJ; Herron, BJ; Kadiyala, SB; Nalwalk, JW; Papandrea, D; Yannix, JQ, 2016) |
| "Kainate also substantially enhances seizure-associated gamma oscillatory activity in juvenile mZnR/GPR39 KO hippocampal slices, a phenomenon that can be reproduced in WT tissue by extracellular Zn(2+) chelation." | 1.42 | Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures. ( Aizenman, E; Friedman, A; Gilad, D; Hershfinkel, M; Ketzef, M; Sekler, I; Shorer, S, 2015) |
| "Control of brain seizures after exposure to nerve agents is imperative for the prevention of brain damage and death." | 1.39 | Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administration. ( Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Green, CE; Qashu, F; Swezey, R; Yang, C, 2013) |
| "The enhanced anti-seizure and neuroprotective effect achieved by disruption of the A1R/neurabin/RGS4 complex is elicited by the on-site and on-demand release of endogenous adenosine, and does not require administration of A1R ligands." | 1.38 | Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine. ( Chen, Y; Cottingham, C; Greengard, P; Jiao, K; Liu, Y; McMahon, L; Wang, Q, 2012) |
| "Imidazenil is an imidazo-benzodiazepine derivative with high intrinsic efficacy and selectivity for α2-, α3-, and α5- but low intrinsic efficacy for α1-containing GABA(A) receptors." | 1.37 | Absence of tolerance to the anticonvulsant and neuroprotective effects of imidazenil against DFP-induced seizure and neuronal damage. ( Auta, J; Davis, JM; Gocel, J; Guidotti, A; Kadriu, B; Larson, J; Nambiar, MP, 2011) |
| "In the H1 receptor KO mice, behavioral seizures were significantly more severe and duration of seizures was significantly longer when compared to the wild type (WT) mice at the KA dose of 2mg/kg." | 1.36 | Involvement of histamine 1 receptor in seizure susceptibility and neuroprotection in immature mice. ( Holopainen, IE; Jalava, N; Kukko-Lukjanov, TK; Laurén, HB; Lintunen, M; Lopez-Picon, FR; Michelsen, KA; Panula, P, 2010) |
| "Spontaneous seizures were detected with video-electroencephalography monitoring and a lowered seizure threshold was determined based on a pentylenetetrazol (PTZ) test." | 1.36 | Association of the severity of cortical damage with the occurrence of spontaneous seizures and hyperexcitability in an animal model of posttraumatic epilepsy. ( Kharatishvili, I; Pitkänen, A, 2010) |
| "Acute kainate-induced seizures resulted in biphasic activation of the mTOR pathway, as evident by an increase in phospho-S6 (P-S6) expression." | 1.35 | The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy. ( Rensing, NR; Wong, M; Zeng, LH, 2009) |
| "Epileptic seizures cause severe and long-lasting events on the architecture of the brain, including neuronal cell death, accompanied neurogenesis, reactive gliosis, and mossy fiber sprouting." | 1.33 | Tonic-clonic seizures induce division of neuronal progenitor cells with concomitant changes in expression of neurotrophic factors in the brain of pilocarpine-treated mice. ( Hagihara, H; Hara, M; Nakagawa, Y; Nakano, K; Sawada, M; Tsunekawa, K, 2005) |
| "Studies of seizure-induced cell death in hybrid and backcross progeny revealed an association between seizure-induced cell death and genotype." | 1.32 | Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death. ( Schauwecker, PE, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 22 (48.89) | 29.6817 |
| 2010's | 18 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, K | 1 |
| Yuan, B | 1 |
| Hu, M | 1 |
| Feng, GF | 1 |
| Liu, Y | 2 |
| Liu, JX | 1 |
| Johnson, AC | 1 |
| Hammer, ES | 1 |
| Sakkaki, S | 1 |
| Tremble, SM | 1 |
| Holmes, GL | 1 |
| Cipolla, MJ | 1 |
| Apland, JP | 3 |
| Aroniadou-Anderjaska, V | 3 |
| Figueiredo, TH | 3 |
| De Araujo Furtado, M | 1 |
| Braga, MFM | 1 |
| Souza, MA | 2 |
| Mota, BC | 1 |
| Gerbatin, RR | 1 |
| Rodrigues, FS | 1 |
| Castro, M | 1 |
| Fighera, MR | 2 |
| Royes, LF | 2 |
| Petkau, TL | 1 |
| Zhu, S | 1 |
| Lu, G | 1 |
| Fernando, S | 1 |
| Cynader, M | 1 |
| Leavitt, BR | 1 |
| Neuberger, EJ | 2 |
| Wahab, RA | 2 |
| Jayakumar, A | 1 |
| Pfister, BJ | 2 |
| Santhakumar, V | 2 |
| Gilad, D | 1 |
| Shorer, S | 1 |
| Ketzef, M | 1 |
| Friedman, A | 1 |
| Sekler, I | 1 |
| Aizenman, E | 1 |
| Hershfinkel, M | 1 |
| Lyeth, BG | 1 |
| Daniel, AG | 1 |
| Laffont, P | 1 |
| Zhao, M | 1 |
| Ma, H | 1 |
| Schwartz, TH | 1 |
| Lin, TY | 1 |
| Lu, CW | 1 |
| Wang, SJ | 1 |
| Kadiyala, SB | 1 |
| Yannix, JQ | 1 |
| Nalwalk, JW | 1 |
| Papandrea, D | 1 |
| Beyer, BS | 1 |
| Herron, BJ | 1 |
| Ferland, RJ | 1 |
| Volosin, M | 1 |
| Trotter, C | 1 |
| Cragnolini, A | 1 |
| Kenchappa, RS | 1 |
| Light, M | 1 |
| Hempstead, BL | 1 |
| Carter, BD | 1 |
| Friedman, WJ | 1 |
| Toscano, CD | 1 |
| Kingsley, PJ | 1 |
| Marnett, LJ | 1 |
| Bosetti, F | 1 |
| Oliveira, MS | 1 |
| Furian, AF | 1 |
| Rambo, LM | 1 |
| Ribeiro, LR | 1 |
| Lima, FD | 1 |
| Dalla Corte, LC | 1 |
| Silva, LF | 1 |
| Retamoso, LT | 1 |
| Dalla Corte, CL | 1 |
| Puntel, GO | 1 |
| de Avila, DS | 1 |
| Soares, FA | 1 |
| de Mello, CF | 1 |
| Zeng, LH | 1 |
| Rensing, NR | 1 |
| Wong, M | 1 |
| Wine, RN | 1 |
| McPherson, CA | 1 |
| Harry, GJ | 1 |
| Jinde, S | 1 |
| Belforte, JE | 1 |
| Yamamoto, J | 1 |
| Wilson, MA | 1 |
| Tonegawa, S | 1 |
| Nakazawa, K | 1 |
| Kukko-Lukjanov, TK | 1 |
| Lintunen, M | 1 |
| Jalava, N | 1 |
| Laurén, HB | 1 |
| Lopez-Picon, FR | 1 |
| Michelsen, KA | 1 |
| Panula, P | 1 |
| Holopainen, IE | 1 |
| Kharatishvili, I | 1 |
| Pitkänen, A | 1 |
| Qashu, F | 2 |
| Souza, AP | 1 |
| Braga, MF | 2 |
| Qian, J | 1 |
| Xu, K | 1 |
| Yoo, J | 1 |
| Chen, TT | 1 |
| Andrews, G | 1 |
| Noebels, JL | 1 |
| Kadriu, B | 1 |
| Gocel, J | 1 |
| Larson, J | 1 |
| Guidotti, A | 1 |
| Davis, JM | 1 |
| Nambiar, MP | 1 |
| Auta, J | 1 |
| Chen, Y | 1 |
| Cottingham, C | 1 |
| McMahon, L | 1 |
| Jiao, K | 1 |
| Greengard, P | 1 |
| Wang, Q | 1 |
| Green, CE | 1 |
| Swezey, R | 1 |
| Yang, C | 1 |
| Schauwecker, PE | 1 |
| Condorelli, DF | 1 |
| Trovato-Salinaro, A | 1 |
| Mudò, G | 1 |
| Mirone, MB | 1 |
| Belluardo, N | 1 |
| Lin, EJ | 1 |
| Richichi, C | 1 |
| Young, D | 1 |
| Baer, K | 1 |
| Vezzani, A | 1 |
| During, MJ | 1 |
| Riba-Bosch, A | 1 |
| Pérez-Clausell, J | 1 |
| Folbergrová, J | 2 |
| Druga, R | 2 |
| Otáhal, J | 2 |
| Haugvicová, R | 2 |
| Mares, P | 2 |
| Kubová, H | 1 |
| Hagihara, H | 1 |
| Hara, M | 1 |
| Tsunekawa, K | 1 |
| Nakagawa, Y | 1 |
| Sawada, M | 1 |
| Nakano, K | 1 |
| Rao, MS | 1 |
| Hattiangady, B | 1 |
| Reddy, DS | 1 |
| Shetty, AK | 1 |
| Bonde, S | 1 |
| Ekdahl, CT | 1 |
| Lindvall, O | 1 |
| Garrido Sanabria, ER | 1 |
| Castañeda, MT | 1 |
| Banuelos, C | 1 |
| Perez-Cordova, MG | 1 |
| Hernandez, S | 1 |
| Colom, LV | 1 |
| Bowyer, JF | 1 |
| Ali, S | 1 |
| McLin, JP | 1 |
| Steward, O | 1 |
| Borges, K | 1 |
| Shaw, R | 1 |
| Dingledine, R | 1 |
| Rangel, A | 1 |
| Burgaya, F | 1 |
| Gavín, R | 1 |
| Soriano, E | 1 |
| Aguzzi, A | 1 |
| Del Río, JA | 1 |
| Galanopoulou, AS | 1 |
| Foresti, ML | 1 |
| Arisi, GM | 1 |
| Fernandes, A | 1 |
| Tilelli, CQ | 1 |
| Garcia-Cairasco, N | 1 |
| Kelly, SP | 1 |
| MacDermott, NJ | 1 |
| Saunders, DC | 1 |
| Leach, FN | 1 |
| Yannuzzi, LA | 1 |
| Rohrer, KT | 1 |
| Tindel, LJ | 1 |
| Sobel, RS | 1 |
| Costanza, MA | 1 |
| Shields, W | 1 |
| Zang, E | 1 |
| Maheshwari, PK | 1 |
| Gulati, A | 1 |
| Sharma, B | 1 |
| Misra, PK | 1 |
| Malik, GK | 1 |
| Kumar, V | 1 |
| Dhawan, BN | 1 |
| Bowen, FP | 1 |
| Brunfeldt, K | 1 |
| Hansen, BA | 1 |
| Jorgesen, KR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Macular Perfusion Changes in Proliferative Diabetic Retinopathy Following Anti-VEGF Therapy Versus Targeted and Pan-retinal Photocoagulation Using Optical Coherence Tomography Angiography[NCT04674254] | Phase 4 | 43 participants (Actual) | Interventional | 2021-03-30 | Active, not recruiting | ||
| Evaluation of the Effect of Repeated Intravitreal Injections of Anti-VEGF on Macular Perfusion in Diabetic Patients Using Optical Coherence Tomography Angiography[NCT03246152] | Phase 4 | 31 participants (Actual) | Interventional | 2017-10-23 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Correlation of BCVA change with degree of capillary non-perfusion before and after injections (NCT03246152)
Timeframe: At baseline and after 3-6 consecutive monthly injections.
| Intervention | Logmar (Mean) |
|---|---|
| Bevacizumab Group | -0.21 |
Effect of repeated intravitreal Anti-VEGF injections on Foveal Avascular Zone (FAZ) area measured using the freehand tool of ImageJ (NCT03246152)
Timeframe: At baseline and after 3-6 consecutive monthly injections.
| Intervention | mm^2 (Mean) |
|---|---|
| Bevacizumab Group | 0.03 |
Effect of repeated intravitreal Anti-VEGF injections on macular capillary density using the change in the skeletonized vascular density and fractal dimension measured by ImageJ (NCT03246152)
Timeframe: At baseline and after 3-6 consecutive monthly injections.
| Intervention | percentage of vascularity (Mean) |
|---|---|
| Bevacizumab Group | -2.5 |
2 reviews available for erythrosine and Seizures
| Article | Year |
|---|---|
Developmental patterns in the regulation of chloride homeostasis and GABA(A) receptor signaling by seizures.
Topics: Animals; Animals, Newborn; Brain; Chlorides; Disease Models, Animal; Fluoresceins; Hippocampus; Home | 2007 |
Fluorescein angiography complication survey.
Topics: Fluorescein; Fluorescein Angiography; Fluoresceins; Health Surveys; Heart Diseases; Humans; Nausea; | 1986 |
Fluorescein angiography complication survey.
Topics: Fluorescein; Fluorescein Angiography; Fluoresceins; Health Surveys; Heart Diseases; Humans; Nausea; | 1986 |
Fluorescein angiography complication survey.
Topics: Fluorescein; Fluorescein Angiography; Fluoresceins; Health Surveys; Heart Diseases; Humans; Nausea; | 1986 |
Fluorescein angiography complication survey.
Topics: Fluorescein; Fluorescein Angiography; Fluoresceins; Health Surveys; Heart Diseases; Humans; Nausea; | 1986 |
43 other studies available for erythrosine and Seizures
| Article | Year |
|---|---|
Reduced abnormal integration of adult-generated granule cells does not attenuate spontaneous recurrent seizures in mice.
Topics: Animals; Bromodeoxyuridine; Cell Count; Disease Models, Animal; Doublecortin Domain Proteins; Female | 2017 |
Inhibition of blood-brain barrier efflux transporters promotes seizure in pregnant rats: Role of circulating factors.
Topics: Animals; Blood-Brain Barrier; Electroencephalography; Estradiol; Female; Fluoresceins; Hippocampus; | 2018 |
Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.
Topics: Animals; Anticonvulsants; Body Weight; Brain Injuries; Brain Waves; Cholinesterase Inhibitors; Cyclo | 2018 |
Antioxidant activity elicited by low dose of caffeine attenuates pentylenetetrazol-induced seizures and oxidative damage in rats.
Topics: Animals; Antioxidants; Buthionine Sulfoximine; Caffeine; Central Nervous System Stimulants; Convulsa | 2013 |
Sensitivity to neurotoxic stress is not increased in progranulin-deficient mice.
Topics: Animals; Fluoresceins; Granulins; Intercellular Signaling Peptides and Proteins; Kainic Acid; Mice; | 2013 |
Distinct effect of impact rise times on immediate and early neuropathology after brain injury in juvenile rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Injuries; Brain Waves; Chi-Square Distributio | 2014 |
Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.
Topics: Action Potentials; Animals; Animals, Newborn; Disease Models, Animal; Edetic Acid; Excitatory Amino | 2015 |
Fluid percussion injury device for the precise control of injury parameters.
Topics: Aging; Animals; Brain Injuries; Disease Models, Animal; Equipment Design; Fluoresceins; Hippocampus; | 2015 |
Optical electrocorticogram (OECoG) using wide-field calcium imaging reveals the divergence of neuronal and glial activity during acute rodent seizures.
Topics: Action Potentials; Aniline Compounds; Animals; Calcium; Diagnostic Imaging; Electrocorticography; Fl | 2015 |
Luteolin protects the hippocampus against neuron impairments induced by kainic acid in rats.
Topics: Animals; CD11b Antigen; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Endopl | 2016 |
Eight Flurothyl-Induced Generalized Seizures Lead to the Rapid Evolution of Spontaneous Seizures in Mice: A Model of Epileptogenesis with Seizure Remission.
Topics: Analysis of Variance; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response R | 2016 |
Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; El | 2008 |
NMDA-induced seizure intensity is enhanced in COX-2 deficient mice.
Topics: Animals; Cyclooxygenase 2; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Fluores | 2008 |
Swimming training prevents pentylenetetrazol-induced inhibition of Na+, K+-ATPase activity, seizures, and oxidative stress.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Catalase; Disease Models, Animal; Elec | 2009 |
The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Cell Death; Disease Models, Animal; Electroencepha | 2009 |
IGF-1 and pAKT signaling promote hippocampal CA1 neuronal survival following injury to dentate granule cells.
Topics: Animals; Animals, Newborn; Brain Injuries; CA1 Region, Hippocampal; Caspase 3; Dentate Gyrus; Diseas | 2009 |
Lack of kainic acid-induced gamma oscillations predicts subsequent CA1 excitotoxic cell death.
Topics: Action Potentials; Analysis of Variance; Animals; Cell Count; Cell Death; Electrophysiology; Excitat | 2009 |
Involvement of histamine 1 receptor in seizure susceptibility and neuroprotection in immature mice.
Topics: Animals; Animals, Newborn; Brain; Cell Count; Chi-Square Distribution; Disease Models, Animal; Disea | 2010 |
Association of the severity of cortical damage with the occurrence of spontaneous seizures and hyperexcitability in an animal model of posttraumatic epilepsy.
Topics: Animals; Atrophy; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electroencephalography; E | 2010 |
Higher susceptibility of the ventral versus the dorsal hippocampus and the posteroventral versus anterodorsal amygdala to soman-induced neuropathology.
Topics: Amygdala; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Disease Susceptibility; Fluore | 2010 |
Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration.
Topics: Animals; CA1 Region, Hippocampal; Cation Transport Proteins; Cell Death; Disease Models, Animal; Ele | 2011 |
Absence of tolerance to the anticonvulsant and neuroprotective effects of imidazenil against DFP-induced seizure and neuronal damage.
Topics: Animals; Anticonvulsants; Benzodiazepines; Cholinesterase Inhibitors; Diazepam; Disease Models, Anim | 2011 |
Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Cell Death; Cells, Cultured | 2012 |
Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administration.
Topics: Animals; Anticonvulsants; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Electroencephalogra | 2013 |
Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death.
Topics: Animals; Cell Count; Cell Death; Chimera; Excitatory Amino Acid Agonists; Female; Fluoresceins; Fluo | 2003 |
Cellular expression of connexins in the rat brain: neuronal localization, effects of kainate-induced seizures and expression in apoptotic neuronal cells.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Autoradiography; Brain; Connexins; Densitometry; Excita | 2003 |
Recombinant AAV-mediated expression of galanin in rat hippocampus suppresses seizure development.
Topics: Animals; Cell Line; Dependovirus; Electroencephalography; Excitatory Amino Acid Agonists; Fluorescei | 2003 |
Response to kainic acid injections: changes in staining for zinc, FOS, cell death and glial response in the rat forebrain.
Topics: Animals; Cell Compartmentation; Cell Death; Cytoplasm; Fluoresceins; Fluorescent Dyes; Gliosis; Glut | 2004 |
Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate.
Topics: Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Brain; Brain Chemistry; B | 2005 |
Tonic-clonic seizures induce division of neuronal progenitor cells with concomitant changes in expression of neurotrophic factors in the brain of pilocarpine-treated mice.
Topics: Acoustic Stimulation; Age Factors; Animals; Blotting, Northern; Brain; Bromodeoxyuridine; CD11b Anti | 2005 |
Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy.
Topics: Animals; Behavior, Animal; Cell Death; Disease Models, Animal; Electroencephalography; Epilepsy, Tem | 2006 |
Long-term neuronal replacement in adult rat hippocampus after status epilepticus despite chronic inflammation.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Count; Disease Mode | 2006 |
Septal GABAergic neurons are selectively vulnerable to pilocarpine-induced status epilepticus and chronic spontaneous seizures.
Topics: Analysis of Variance; Animals; Cell Survival; Disease Models, Animal; Fluoresceins; gamma-Aminobutyr | 2006 |
High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus.
Topics: Amphetamine-Related Disorders; Amygdala; Animals; Blood-Brain Barrier; Body Temperature; Central Ner | 2006 |
Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains.
Topics: Animals; Cell Count; Dentate Gyrus; Drug Resistance; Excitatory Amino Acid Agonists; Fluoresceins; F | 2006 |
Gene expression changes after seizure preconditioning in the three major hippocampal cell layers.
Topics: Animals; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Gene Amplification; Gene Ex | 2007 |
Enhanced susceptibility of Prnp-deficient mice to kainate-induced seizures, neuronal apoptosis, and death: Role of AMPA/kainate receptors.
Topics: Animals; Apoptosis; Disease Susceptibility; Fluoresceins; Hippocampus; Kainic Acid; Mice; Mice, Inbr | 2007 |
Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Benzoates; Brain; Dose-Response Relati | 2008 |
Chelatable zinc modulates excitability and seizure duration in the amygdala rapid kindling model.
Topics: Amygdala; Animals; Chelating Agents; Ditiocarb; Electroencephalography; Electrophysiology; Fluoresce | 2008 |
Convulsion following intravenous fluorescein angiography.
Topics: Fluorescein; Fluorescein Angiography; Fluoresceins; Humans; Injections, Intravenous; Male; Middle Ag | 1989 |
Blood-brain barrier in non-infective convulsive disorders.
Topics: Blood-Brain Barrier; Carbohydrates; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Child; Child, | 1985 |
Immunologic reactions after cortical lesions in rabbits.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Cerebral Cortex; Corpus Callosum; Electroen | 1968 |
The immunological reactivity and biological activity of iodinated insulin.
Topics: Adipose Tissue; Animals; Antigen-Antibody Reactions; Biological Assay; Chromatography, Gel; Electrop | 1968 |