Page last updated: 2024-08-21

1,2,4-triazole and Seizures

1,2,4-triazole has been researched along with Seizures in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Liu, D; Wang, Y1
Chen, L; Hou, Z; Huang, L; Li, X; Lian, C; Meng, Q; Wang, Y; Wu, J; Yu, H; Zhang, C1
Gryboś, A; Głuch-Lutwin, M; Jóźwiak, K; Kaproń, B; Karcz, T; Mordyl, B; Nowak, G; Pająk, K; Paneth, A; Plech, T; Siwek, A; Tomczykowski, A; Wujec, M; Łuszczki, J1
Dalkara, S; Kaynak, FB; Sari, S1
Cielecka-Piontek, J; Ciesla, LM; Gryboś, A; Kaproń, B; Karcz, T; Langner, E; Makuch-Kocka, A; Marciniak, S; Nowak, G; Paczkowska, M; Plech, T; Płazińska, A; Siwek, A; Szalast, K; Walczak, K; Łuszczki, JJ1
Dhanda, A; Kamboj, VK; Ranjan, S; Verma, PK1
Flieger, J; Luszczki, JJ; Pizoń, M; Plech, T; Wujec, M1
AINSWORTH, C; EASTON, NR; GIBSON, WR; LIVEZEY, M; MORRISON, DE1

Reviews

2 review(s) available for 1,2,4-triazole and Seizures

ArticleYear
An Important Potential Anti-Epileptic/Anticonvulsant Active Group: A Review of 1,2,4-Triazole Groups and Their Action.
    Drug research, 2022, Volume: 72, Issue:3

    Topics: Anticonvulsants; Epilepsy; Humans; Seizures; Triazoles

2022
1,2,4-triazole derivatives as potential scaffold for anticonvulsant activity.
    Central nervous system agents in medicinal chemistry, 2015, Volume: 15, Issue:1

    Topics: Animals; Anticonvulsants; Epilepsy; Humans; Seizures; Structure-Activity Relationship; Triazoles

2015

Other Studies

6 other study(ies) available for 1,2,4-triazole and Seizures

ArticleYear
Discovery of 7-alkyloxy- [1,2,4] triazolo[1,5-a] pyrimidine derivatives as selective positive modulators of GABA
    Bioorganic chemistry, 2022, Volume: 119

    Topics: Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Electroshock; Epilepsy; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neurons; Pentylenetetrazole; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Triazoles

2022
Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3
    International journal of medical sciences, 2017, Volume: 14, Issue:8

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Hep G2 Cells; Humans; Mice; Patch-Clamp Techniques; Seizures; Thiones; Triazoles; Voltage-Gated Sodium Channels

2017
Synthesis and anticonvulsant screening of 1,2,4-triazole derivatives.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:6

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Triazoles; X-Ray Diffraction

2018
Development of the 1,2,4-triazole-based anticonvulsant drug candidates acting on the voltage-gated sodium channels. Insights from in-vivo, in-vitro, and in-silico studies.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Mar-01, Volume: 129

    Topics: Animals; Anticonvulsants; Cell Line; Cell Line, Tumor; Cell Membrane Permeability; Computer Simulation; Electroshock; HEK293 Cells; Hep G2 Cells; Humans; Mice; Molecular Docking Simulation; Receptors, GABA-A; Seizures; Triazoles; Voltage-Gated Sodium Channels

2019
Synthesis, characterization and preliminary anticonvulsant evaluation of some 4-alkyl-1,2,4-triazoles.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Animals; Anticonvulsants; Electroshock; Male; Mice; Molecular Structure; Seizures; Triazoles

2013
THE ANTICONVULSANT ACTIVITY OF 1,2,4-TRIAZOLES.
    Journal of medicinal and pharmaceutical chemistry, 1962, Volume: 5

    Topics: Anticonvulsants; Central Nervous System Stimulants; Pharmacology; Rats; Research; Seizures; Triazoles

1962