famotidine has been researched along with Seizures in 3 studies
Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Adjusting the maintenance dosage of H(2)-histamine antagonists has been recommended in elderly patients since age-related reduction in renal plasma flow, glomerular filtration rate and renal tubular function may be present, which can in turn elevate histamine levels in plasma and cerebrospinal fluid." | 5.31 | H(2)-histamine antagonist (famotidine) induced adverse CNS reactions with long-standing secondary mania and epileptic seizures. ( Bergemann, N; Diebold, K; Mundt, C; Roesch-Ely, D; Sartor, K; von Einsiedel, RW, 2002) |
| " Adjusting the maintenance dosage of H(2)-histamine antagonists has been recommended in elderly patients since age-related reduction in renal plasma flow, glomerular filtration rate and renal tubular function may be present, which can in turn elevate histamine levels in plasma and cerebrospinal fluid." | 1.31 | H(2)-histamine antagonist (famotidine) induced adverse CNS reactions with long-standing secondary mania and epileptic seizures. ( Bergemann, N; Diebold, K; Mundt, C; Roesch-Ely, D; Sartor, K; von Einsiedel, RW, 2002) |
| "Dose dependency of clonic and/or tonic convulsion was observed, and the ED50 values of convulsive occurrence for cimetidine, ranitidine, famotidine, and nizatidine were 997, 662, 23." | 1.29 | Neurotoxic convulsions induced by histamine H2 receptor antagonists in mice. ( Iga, T; Kawakami, J; Sawada, Y; Shimokawa, M; Yamamoto, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, YI | 1 |
| Park, CK | 1 |
| Park, DJ | 1 |
| Wi, JO | 1 |
| Han, ER | 1 |
| Koh, YI | 1 |
| von Einsiedel, RW | 1 |
| Roesch-Ely, D | 1 |
| Diebold, K | 1 |
| Sartor, K | 1 |
| Mundt, C | 1 |
| Bergemann, N | 1 |
| Shimokawa, M | 1 |
| Yamamoto, K | 1 |
| Kawakami, J | 1 |
| Sawada, Y | 1 |
| Iga, T | 1 |
3 other studies available for famotidine and Seizures
| Article | Year |
|---|---|
A case of famotidine-induced anaphylaxis.
Topics: Adrenal Cortex Hormones; Anaphylaxis; Coma; Cross Reactions; Drug Hypersensitivity; Dyspnea; Epineph | 2010 |
H(2)-histamine antagonist (famotidine) induced adverse CNS reactions with long-standing secondary mania and epileptic seizures.
Topics: Aged; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Epilepsy; Famotidine; Fema | 2002 |
Neurotoxic convulsions induced by histamine H2 receptor antagonists in mice.
Topics: Animals; Anticonvulsants; Brain; Cimetidine; Convulsants; Famotidine; GABA Agonists; Histamine H2 An | 1996 |