creatine has been researched along with Seizures in 58 studies
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present work, synchrotron radiation Fourier-transform infrared (SRFTIR) and Raman microspectroscopies were used to evaluate a possible role of creatine in the pathogenesis and progress of pilocarpine-evoked seizures and seizure-induced neurodegenerative changes in the rat hippocampal tissue." | 7.78 | Synchrotron radiation Fourier-transform infrared and Raman microspectroscopy study showing an increased frequency of creatine inclusions in the rat hippocampal formation following pilocarpine-induced seizures. ( Chwiej, J; Dulinska, J; Dumas, P; Gzielo-Jurek, K; Janeczko, K; Sandt, C; Setkowicz, Z; Uram, L, 2012) |
| "Epilepsy is often considered to be a progressive neurological disease, and the nature of this progression remains unclear." | 5.72 | Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes. ( Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X, 2022) |
| "The intensity of convulsion was scored according to a seven-point scale ranging from stage 0-7." | 5.62 | Creatine attenuates seizure severity, anxiety and depressive-like behaviors in pentylenetetrazole kindled mice. ( Abiola, AL; Akhigbemen, AM; Chinazamoku, O; Igbe, I; Ogundepo, GE; Okwuofu, EO; Ozolua, RI, 2021) |
| "The incidence of clinical seizures is highest in the newborn period." | 5.30 | Creatine increases survival and suppresses seizures in the hypoxic immature rat. ( Holtzman, D; Jensen, F; Khait, I; Togliatti, A, 1998) |
| "Sustained, generalized seizure activity was induced in anaesthetized (70% N2O), paralyzed and artifically ventilated rats by i." | 5.26 | Cerebral metabolic and circulatory changes in the rat during sustained seizures induced by DL-homocysteine. ( Blennow, G; Folbergrova, J; Nilsson, B; Siesjö, BK, 1979) |
| "Cerebral creatine deficiency syndrome (CCDS) is an inborn error of metabolism characterized by intellectual delays, seizures, and autistic-like behavior." | 4.31 | Cerebral Creatine Deficiency Affects the Timing of Oligodendrocyte Myelination. ( Albanese, C; Gentile, T; Hu, J; Huang, JK; Lee, Y; Manavi, Z; Melchor, GS; Rodriguez, O; Rosko, LM; Shults, NV; Smith, VN, 2023) |
| "Creatine Transporter Deficiency (CTD) is an inborn error of metabolism presenting with intellectual disability, behavioral disturbances and epilepsy." | 3.96 | Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency. ( Alessandrì, MG; Baroncelli, L; Battini, R; Butt, M; Cacciante, F; Cerri, E; Cioni, G; Do, MT; Gennaro, M; Lupori, L; Mazziotti, R; McKew, JC; Pizzorusso, T; Putignano, E; Sagona, G, 2020) |
| "Compared to nonpregnant women, women with normal pregnancy and preeclampsia had lower levels of the cerebral osmolytes, myo-inositol, choline and creatine (P = 0." | 3.88 | Cerebral Osmolytes and Plasma Osmolality in Pregnancy and Preeclampsia: A Proton Magnetic Resonance Spectroscopy Study. ( Bergman, L; Larsson, A; Nelander, M; Sundström-Poromaa, I; Weis, J; Wikström, AK; Wikström, J, 2018) |
| " Brain creatine depletion and guanidinoacetate accumulation cause developmental delay, seizures and movement disorder." | 3.88 | Treatment outcome of twenty-two patients with guanidinoacetate methyltransferase deficiency: An international retrospective cohort study. ( Abdenur, J; Anastasi, A; Ballhausen, D; Billette de Villemeur, T; Buoni, S; Chan, A; Cheillan, D; Dorison, N; Goldenberg, A; Goldstein, J; Hofstede, FC; Jacquemont, ML; Khaikin, Y; Koeberl, DD; Lion-Francois, L; Lund, AM; Mention, K; Mercimek-Andrews, S; Mundy, H; O'Rourke, D; Pitelet, G; Raspall-Chaure, M; Salomons, GS; Sidky, S; Tassini, M; Williams, M, 2018) |
| "X-linked creatine transporter deficiency (OMIM#300036,CRTR-D) is characterized by cerebral creatine deficiency, intellectual disabilities, severe speech impairment, seizures and behavioral problems." | 3.88 | A novel SLC6A8 mutation associated with intellectual disabilities in a Chinese family exhibiting creatine transporter deficiency: case report. ( Li, X; Liu, Y; Luo, F; Wang, Q; Xie, J; Yang, J, 2018) |
| "In the present work, synchrotron radiation Fourier-transform infrared (SRFTIR) and Raman microspectroscopies were used to evaluate a possible role of creatine in the pathogenesis and progress of pilocarpine-evoked seizures and seizure-induced neurodegenerative changes in the rat hippocampal tissue." | 3.78 | Synchrotron radiation Fourier-transform infrared and Raman microspectroscopy study showing an increased frequency of creatine inclusions in the rat hippocampal formation following pilocarpine-induced seizures. ( Chwiej, J; Dulinska, J; Dumas, P; Gzielo-Jurek, K; Janeczko, K; Sandt, C; Setkowicz, Z; Uram, L, 2012) |
| "Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by striatal degeneration, seizures, and accumulation of glutaric acid (GA)." | 3.74 | Creatine decreases convulsions and neurochemical alterations induced by glutaric acid in rats. ( Ferreira, J; Fighera, MR; Fiorenza, NG; Furian, AF; Magni, DV; Mello, CF; Oliveira, MS; Royes, LF, 2007) |
| "Rats in experiment 1 received 1% creatine or cyclocreatine chow from age (P) 21-65 days, underwent kainate induced status epilepticus on P35 and were compared, as adults, to kainate alone rats and to normal controls." | 3.72 | Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats. ( Abu Rialy, S; Farhat, F; Francis, E; Geha, G; Kurdit, RM; Lteif, L; Maraashli, W; Mikati, MA; Rahmeh, AA, 2004) |
| "To study the effects of creatine (Cr) on brain energy metabolism and on hypoxia-induced seizures, 5- to 30-day-old rabbit pups were given subcutaneous Cr (3 g/kg) for 3 days before exposure to 4% O2 for 8 min." | 3.70 | In vivo development of brain phosphocreatine in normal and creatine-treated rabbit pups. ( Allred, E; Holtzman, D; Jensen, F; Khait, I; Kraft, R; Mulkern, R; Rand, T, 1999) |
| " After 6 h of recovery following transient forebrain ischemia 15 min in duration, bicuculline seizures were induced, and brains were frozen in situ after 0." | 3.69 | Functional, metabolic, and circulatory changes associated with seizure activity in the postischemic brain. ( Folbergrová, J; Gidö, G; Katsura, K; Siesjö, BK, 1994) |
| "Linear regression analyses between seizure duration and NAA/Cr decrease was not significant." | 2.69 | Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy. ( Andermann, F; Arnold, DL; Cendes, F; Dubeau, F; Li, LM; Miller, SP; Tasch, E, 2000) |
| "Lack of CRE in the brain can cause intellectual disability, autistic-like behavior, seizures, and movement disorders." | 1.72 | Method modification to reduce false positives for newborn screening of guanidinoacetate methyltransferase deficiency. ( Borden, K; Caggana, M; Morrissey, M; Showers, A; Sicko, R; Sunny, S; Teta, B; Wojcik, M, 2022) |
| "Epilepsy is often considered to be a progressive neurological disease, and the nature of this progression remains unclear." | 1.72 | Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes. ( Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X, 2022) |
| "The intensity of convulsion was scored according to a seven-point scale ranging from stage 0-7." | 1.62 | Creatine attenuates seizure severity, anxiety and depressive-like behaviors in pentylenetetrazole kindled mice. ( Abiola, AL; Akhigbemen, AM; Chinazamoku, O; Igbe, I; Ogundepo, GE; Okwuofu, EO; Ozolua, RI, 2021) |
| " When dosed at 300 mg/kg/day for 3 months, cyclocreatine-related mortality, convulsions, and multi-organ pathology were observed in wild-type mice whereas there were no adverse findings in creatine transporter-deficient mice." | 1.62 | Use of an animal model of disease for toxicology enables identification of a juvenile no observed adverse effect level for cyclocreatine in creatine transporter deficiency. ( Butt, M; Cavagnaro, J; Do, MT; McKew, JC; Terse, PS, 2021) |
| "These 2 patients presented with seizures." | 1.46 | Magnetic Resonance Spectroscopy Findings in Patients with Dural Arteriovenous Fistulas: Three Case Reports. ( Fujita, A; Hosoda, K; Kohmura, E; Kohta, M; Nagashima, H; Sasayama, T; Tanaka, J; Tanaka, K, 2017) |
| "Semiology, seizure frequency, and therapy were assessed for all patients." | 1.46 | Proton MR Spectroscopy in Patients With Sleep-Related Hypermotor Epilepsy (SHE): Evidence of Altered Cingulate Cortex Metabolism. ( Bisulli, F; Ferri, L; Gramegna, LL; Licchetta, L; Lodi, R; Naldi, I; Rizzo, G; Testa, C; Tinuper, P; Tonon, C, 2017) |
| "The ketogenic diet did not modify the seizure induced anomalies in the unsaturation level of lipids or the number of creatine deposits." | 1.42 | The biochemical changes in hippocampal formation occurring in normal and seizure experiencing rats as a result of a ketogenic diet. ( Chwiej, J; Dumas, P; Figiel, H; Janeczko, K; Kutorasinska, J; Matusiak, K; Sandt, C; Setkowicz, Z; Skoczen, A, 2015) |
| "Pilomotor seizure (PS) is a rare subtype of simple and complex partial seizures, often related to temporal lobe epilepsy and occasionally linked to alterations of amygdala." | 1.36 | Dissociation between neurovegetative signs and subjective symptoms in a case of idiopathic pilomotor seizures. ( Balestrieri, A; Barberini, L; Bortolato, M; Genugu, F; Gioi, G; Marrosu, F; Puligheddu, M, 2010) |
| "The age of onset of seizures usually ranges from infancy to 3 years." | 1.35 | Expanded clinical and molecular spectrum of guanidinoacetate methyltransferase (GAMT) deficiency. ( Abdenur, JE; Barshop, BA; Chen, E; Dhar, SU; Eng, CM; Haas, RH; Hunter, JV; Li, FY; Lotze, T; Maranda, B; O'Brien, W; Scaglia, F; Smith, L; Willis, M; Wong, LJ, 2009) |
| "These data argue that within the seizure onset zone, the tight correlation between total power and NAA/Cr suggests that total electrical output is powered by available mitochondrial function." | 1.35 | Intracranial EEG power and metabolism in human epilepsy. ( Hetherington, HP; Pan, JW; Spencer, DD; Spencer, SS; Zaveri, HP, 2009) |
| "Seizures were analyzed by: number of clinical seizures in 24 h, exact duration of clinical symptoms in 24 h, frequency of interictal epileptiform discharges (IEDs) and ictal activity, duration of ictal activity, and IEDs occurring within 24 h in intensive EEG monitoring." | 1.34 | 1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG. ( Doelken, M; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Kerling, F; Nimsky, C; Schwarz, M; Stadlbauer, A; Stefan, H, 2007) |
| "Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging." | 1.31 | Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome. ( Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ, 2002) |
| "During seizures, CK-catalyzed fluxes increased only in GPA-fed mice." | 1.30 | In vivo brain phosphocreatine and ATP regulation in mice fed a creatine analog. ( Allred, E; Holtzman, D; Jensen, F; Khait, I; Meyers, R; O'Gorman, E; Wallimann, T, 1997) |
| "Kainic acid (KA)-induced seizures lead to histopathologic changes in rat brain." | 1.30 | MRS metabolic markers of seizures and seizure-induced neuronal damage. ( Comair, YG; Lüders, HO; Najm, IM; Ng, TC; Shedid, D; Wang, Y, 1998) |
| "The incidence of clinical seizures is highest in the newborn period." | 1.30 | Creatine increases survival and suppresses seizures in the hypoxic immature rat. ( Holtzman, D; Jensen, F; Khait, I; Togliatti, A, 1998) |
| "Sustained, generalized seizure activity was induced in anaesthetized (70% N2O), paralyzed and artifically ventilated rats by i." | 1.26 | Cerebral metabolic and circulatory changes in the rat during sustained seizures induced by DL-homocysteine. ( Blennow, G; Folbergrova, J; Nilsson, B; Siesjö, BK, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (17.24) | 18.7374 |
| 1990's | 5 (8.62) | 18.2507 |
| 2000's | 17 (29.31) | 29.6817 |
| 2010's | 16 (27.59) | 24.3611 |
| 2020's | 10 (17.24) | 2.80 |
| Authors | Studies |
|---|---|
| Wan, X | 1 |
| Liu, L | 1 |
| Wang, W | 1 |
| Tan, Q | 1 |
| Su, X | 1 |
| Zhang, S | 1 |
| Yang, X | 1 |
| Yue, Q | 1 |
| Gong, Q | 1 |
| Wojcik, M | 1 |
| Morrissey, M | 1 |
| Borden, K | 1 |
| Teta, B | 1 |
| Sicko, R | 1 |
| Showers, A | 1 |
| Sunny, S | 1 |
| Caggana, M | 1 |
| Zhao, X | 1 |
| Cheng, P | 1 |
| Xu, R | 1 |
| Meng, K | 1 |
| Liao, S | 1 |
| Jia, P | 1 |
| Zheng, X | 1 |
| Xiao, C | 1 |
| Moravej, H | 1 |
| Inaloo, S | 1 |
| Nahid, S | 1 |
| Mazloumi, S | 1 |
| Nemati, H | 1 |
| Moosavian, T | 1 |
| Nasiri, J | 1 |
| Ghasemi, F | 1 |
| Alaei, MR | 1 |
| Dalili, S | 1 |
| Aminzadeh, M | 1 |
| Katibeh, P | 1 |
| Amirhakimi, A | 1 |
| Yazdani, N | 1 |
| Ilkhanipoor, H | 1 |
| Afshar, Z | 1 |
| Hadipour, F | 1 |
| Hadipour, Z | 1 |
| Rosko, LM | 1 |
| Gentile, T | 1 |
| Smith, VN | 1 |
| Manavi, Z | 1 |
| Melchor, GS | 1 |
| Hu, J | 1 |
| Shults, NV | 1 |
| Albanese, C | 1 |
| Lee, Y | 1 |
| Rodriguez, O | 1 |
| Huang, JK | 1 |
| Cacciante, F | 1 |
| Gennaro, M | 1 |
| Sagona, G | 1 |
| Mazziotti, R | 1 |
| Lupori, L | 1 |
| Cerri, E | 1 |
| Putignano, E | 1 |
| Butt, M | 2 |
| Do, MT | 2 |
| McKew, JC | 2 |
| Alessandrì, MG | 1 |
| Battini, R | 1 |
| Cioni, G | 1 |
| Pizzorusso, T | 1 |
| Baroncelli, L | 1 |
| Simani, L | 1 |
| Raminfard, S | 1 |
| Asadollahi, M | 1 |
| Roozbeh, M | 1 |
| Ryan, F | 1 |
| Rostami, M | 1 |
| Okwuofu, EO | 1 |
| Ogundepo, GE | 1 |
| Akhigbemen, AM | 1 |
| Abiola, AL | 1 |
| Ozolua, RI | 1 |
| Igbe, I | 1 |
| Chinazamoku, O | 1 |
| Cavagnaro, J | 1 |
| Terse, PS | 1 |
| Lopez-Marin, L | 1 |
| Nagashima, H | 1 |
| Fujita, A | 1 |
| Tanaka, J | 1 |
| Kohta, M | 1 |
| Sasayama, T | 1 |
| Tanaka, K | 1 |
| Hosoda, K | 1 |
| Kohmura, E | 1 |
| Naldi, I | 1 |
| Bisulli, F | 1 |
| Testa, C | 1 |
| Rizzo, G | 1 |
| Ferri, L | 1 |
| Gramegna, LL | 1 |
| Licchetta, L | 1 |
| Lodi, R | 1 |
| Tonon, C | 1 |
| Tinuper, P | 1 |
| Nelander, M | 1 |
| Wikström, AK | 1 |
| Weis, J | 1 |
| Bergman, L | 1 |
| Larsson, A | 1 |
| Sundström-Poromaa, I | 1 |
| Wikström, J | 1 |
| Bruun, TUJ | 1 |
| Sidky, S | 2 |
| Bandeira, AO | 1 |
| Debray, FG | 1 |
| Ficicioglu, C | 1 |
| Goldstein, J | 2 |
| Joost, K | 1 |
| Koeberl, DD | 2 |
| Luísa, D | 1 |
| Nassogne, MC | 1 |
| O'Sullivan, S | 1 |
| Õunap, K | 1 |
| Schulze, A | 1 |
| van Maldergem, L | 1 |
| Salomons, GS | 2 |
| Mercimek-Andrews, S | 2 |
| Khaikin, Y | 1 |
| Abdenur, J | 1 |
| Anastasi, A | 1 |
| Ballhausen, D | 1 |
| Buoni, S | 1 |
| Chan, A | 1 |
| Cheillan, D | 1 |
| Dorison, N | 1 |
| Goldenberg, A | 1 |
| Hofstede, FC | 1 |
| Jacquemont, ML | 1 |
| Lion-Francois, L | 1 |
| Lund, AM | 1 |
| Mention, K | 1 |
| Mundy, H | 1 |
| O'Rourke, D | 1 |
| Pitelet, G | 1 |
| Raspall-Chaure, M | 1 |
| Tassini, M | 1 |
| Billette de Villemeur, T | 1 |
| Williams, M | 1 |
| Lee, DH | 1 |
| Lee, DW | 1 |
| Kwon, JI | 1 |
| Woo, CW | 1 |
| Kim, ST | 1 |
| Lee, JS | 1 |
| Choi, CG | 1 |
| Kim, KW | 1 |
| Kim, JK | 1 |
| Woo, DC | 1 |
| Hall, J | 1 |
| Frenguelli, BG | 1 |
| Chwiej, JG | 1 |
| Ciesielka, SW | 1 |
| Skoczen, AK | 1 |
| Janeczko, KJ | 1 |
| Sandt, C | 3 |
| Planeta, KL | 1 |
| Setkowicz, ZK | 1 |
| Wang, Q | 1 |
| Yang, J | 1 |
| Liu, Y | 1 |
| Li, X | 1 |
| Luo, F | 1 |
| Xie, J | 1 |
| Gerbatin, RR | 1 |
| Silva, LFA | 1 |
| Hoffmann, MS | 1 |
| Della-Pace, ID | 2 |
| do Nascimento, PS | 1 |
| Kegler, A | 1 |
| de Zorzi, VN | 1 |
| Cunha, JM | 1 |
| Botelho, P | 1 |
| Neto, JBT | 1 |
| Furian, AF | 6 |
| Oliveira, MS | 6 |
| Fighera, MR | 6 |
| Royes, LFF | 1 |
| Rostami, P | 1 |
| Hosseinpour, S | 1 |
| Ashrafi, MR | 1 |
| Alizadeh, H | 1 |
| Garshasbi, M | 1 |
| Tavasoli, AR | 1 |
| Chwiej, J | 2 |
| Skoczen, A | 1 |
| Janeczko, K | 2 |
| Kutorasinska, J | 1 |
| Matusiak, K | 1 |
| Figiel, H | 1 |
| Dumas, P | 2 |
| Setkowicz, Z | 2 |
| Pacheva, I | 1 |
| Ivanov, I | 1 |
| Penkov, M | 1 |
| Kancheva, D | 1 |
| Jordanova, A | 1 |
| Ivanova, M | 1 |
| Simister, RJ | 1 |
| McLean, MA | 1 |
| Salmenpera, TM | 1 |
| Barker, GJ | 1 |
| Duncan, JS | 1 |
| Dericioglu, N | 1 |
| Garganta, CL | 1 |
| Petroff, OA | 1 |
| Mendelsohn, D | 1 |
| Williamson, A | 1 |
| Dhar, SU | 1 |
| Scaglia, F | 1 |
| Li, FY | 1 |
| Smith, L | 1 |
| Barshop, BA | 1 |
| Eng, CM | 1 |
| Haas, RH | 1 |
| Hunter, JV | 1 |
| Lotze, T | 1 |
| Maranda, B | 1 |
| Willis, M | 1 |
| Abdenur, JE | 1 |
| Chen, E | 1 |
| O'Brien, W | 1 |
| Wong, LJ | 1 |
| Rambo, LM | 2 |
| Ribeiro, LR | 2 |
| Lima, FD | 1 |
| Souza, MA | 1 |
| Silva, LF | 1 |
| Retamoso, LT | 1 |
| Corte, CL | 1 |
| Puntel, GO | 1 |
| de Avila, DS | 1 |
| Soares, FA | 1 |
| Mello, CF | 4 |
| Royes, LF | 5 |
| Pan, JW | 1 |
| Zaveri, HP | 1 |
| Spencer, DD | 1 |
| Hetherington, HP | 1 |
| Spencer, SS | 1 |
| Puligheddu, M | 1 |
| Bortolato, M | 1 |
| Barberini, L | 1 |
| Genugu, F | 1 |
| Gioi, G | 1 |
| Balestrieri, A | 1 |
| Marrosu, F | 1 |
| Dulinska, J | 1 |
| Uram, L | 1 |
| Gzielo-Jurek, K | 1 |
| Stamm, DN | 1 |
| da Rosa Gerbatin, R | 1 |
| Prigol, M | 1 |
| Pinton, S | 1 |
| Nogueira, CW | 1 |
| Hájek, M | 1 |
| Dezortová, M | 1 |
| Liscák, R | 1 |
| Vymazal, J | 1 |
| Vladyka, V | 1 |
| da Silva, LG | 1 |
| Malfatti, CR | 1 |
| Schneider, PH | 1 |
| Braga, AL | 1 |
| Wajner, M | 1 |
| SALISBURY, PF | 1 |
| POMERANZ, AA | 1 |
| CORNISH, HH | 1 |
| BARTH, ML | 1 |
| REINS, DA | 1 |
| HOLMES, DD | 1 |
| HINSHAW, LB | 1 |
| Bassuk, AG | 1 |
| Joshi, A | 1 |
| Burton, BK | 1 |
| Larsen, MB | 1 |
| Burrowes, DM | 1 |
| Stack, C | 1 |
| CHEYMOL, J | 1 |
| GAY, Y | 1 |
| Mikati, MA | 1 |
| Kurdit, RM | 1 |
| Rahmeh, AA | 1 |
| Farhat, F | 1 |
| Abu Rialy, S | 1 |
| Lteif, L | 1 |
| Francis, E | 1 |
| Geha, G | 1 |
| Maraashli, W | 1 |
| Brissaud, O | 1 |
| Chateil, JF | 1 |
| Bordessoules, M | 1 |
| Brun, M | 1 |
| Myskiw, Jde C | 1 |
| Fiorenza, NG | 2 |
| Petry, JC | 1 |
| Coelho, RC | 1 |
| Hammen, T | 1 |
| Schwarz, M | 1 |
| Doelken, M | 1 |
| Kerling, F | 1 |
| Engelhorn, T | 1 |
| Stadlbauer, A | 1 |
| Ganslandt, O | 1 |
| Nimsky, C | 1 |
| Doerfler, A | 1 |
| Stefan, H | 1 |
| Riederer, F | 1 |
| Bittsanský, M | 1 |
| Lehner-Baumgartner, E | 1 |
| Baumgartner, C | 1 |
| Mlynárik, V | 1 |
| Gruber, S | 1 |
| Moser, E | 1 |
| Kaya, M | 1 |
| Serles, W | 1 |
| Magni, DV | 1 |
| Ferreira, J | 1 |
| Katsura, K | 1 |
| Folbergrová, J | 2 |
| Gidö, G | 1 |
| Siesjö, BK | 4 |
| Holtzman, D | 3 |
| Meyers, R | 1 |
| O'Gorman, E | 1 |
| Khait, I | 3 |
| Wallimann, T | 1 |
| Allred, E | 2 |
| Jensen, F | 3 |
| Najm, IM | 1 |
| Wang, Y | 1 |
| Shedid, D | 1 |
| Lüders, HO | 1 |
| Ng, TC | 1 |
| Comair, YG | 1 |
| Togliatti, A | 1 |
| Mulkern, R | 1 |
| Rand, T | 1 |
| Kraft, R | 1 |
| Miller, SP | 1 |
| Li, LM | 1 |
| Cendes, F | 1 |
| Tasch, E | 1 |
| Andermann, F | 1 |
| Dubeau, F | 1 |
| Arnold, DL | 1 |
| Hiramatsu, M | 1 |
| Eichler, FS | 1 |
| Wang, P | 1 |
| Wityk, RJ | 1 |
| Beauchamp, NJ | 1 |
| Barker, PB | 1 |
| Chapman, AG | 1 |
| Meldrum, BS | 1 |
| Blennow, G | 1 |
| Nilsson, B | 1 |
| Lewis, LD | 1 |
| Ljunggren, B | 1 |
| Ratcheson, RA | 1 |
| Howse, DC | 1 |
| Caronna, JJ | 1 |
| Duffy, TE | 1 |
| Plum, F | 1 |
| Love, DW | 1 |
| Salter, FJ | 1 |
| Ferendelli, JA | 1 |
| McDougal, DB | 1 |
3 reviews available for creatine and Seizures
| Article | Year |
|---|---|
[Metabolic approach in epileptic encephalopathies in infants].
Topics: Age of Onset; Biotin; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Child, Preschool | 2017 |
Primary creatine deficiency syndrome as a potential missed diagnosis in children with psychomotor delay and seizure: case presentation with two novel variants and literature review.
Topics: Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Creatine; Delayed Diagnosis; Development | 2020 |
[Functions of guanidino compounds in brain].
Topics: Amino Acids; Animals; Brain; Creatine; Free Radicals; Guanidines; Humans; Neurotransmitter Agents; O | 2001 |
1 trial available for creatine and Seizures
| Article | Year |
|---|---|
Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy.
Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Aspartic Acid; Brain Neoplasms; Child; C | 2000 |
54 other studies available for creatine and Seizures
| Article | Year |
|---|---|
1H-MRS reveals metabolic alterations in generalized tonic-clonic seizures before and after treatment.
Topics: Aspartic Acid; Creatine; Dorsolateral Prefrontal Cortex; Humans; Magnetic Resonance Spectroscopy; Pr | 2022 |
Method modification to reduce false positives for newborn screening of guanidinoacetate methyltransferase deficiency.
Topics: Creatine; Guanidinoacetate N-Methyltransferase; Humans; Infant, Newborn; Intellectual Disability; La | 2022 |
Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes.
Topics: Alanine; Animals; Anticonvulsants; Asparagine; Citrates; Creatine; Creatinine; Disease Models, Anima | 2022 |
Inborn Errors of Metabolism Associated With Autism Among Children: A Multicenter Study from Iran.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Autism Spectrum Disorder; Autistic Di | 2023 |
Cerebral Creatine Deficiency Affects the Timing of Oligodendrocyte Myelination.
Topics: Animals; Creatine; Demyelinating Diseases; Female; Homozygote; Intellectual Disability; Male; Mice; | 2023 |
Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency.
Topics: Animals; Autistic Disorder; Blood-Brain Barrier; Brain Diseases, Metabolic, Inborn; Cerebrovascular | 2020 |
Neurochemicals of limbic system and thalamofrontal cortical network: Are they different between patients with idiopathic generalized epilepsy and psychogenic nonepileptic seizure?
Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Generalized; Humans; Magnetic Resonance Spectrosc | 2020 |
Creatine attenuates seizure severity, anxiety and depressive-like behaviors in pentylenetetrazole kindled mice.
Topics: Animals; Anxiety; Convulsants; Creatine; Depression; Dose-Response Relationship, Drug; Glutathione; | 2021 |
Use of an animal model of disease for toxicology enables identification of a juvenile no observed adverse effect level for cyclocreatine in creatine transporter deficiency.
Topics: Animals; Antineoplastic Agents; Brain; Brain Diseases, Metabolic, Inborn; Creatine; Creatinine; Dise | 2021 |
Magnetic Resonance Spectroscopy Findings in Patients with Dural Arteriovenous Fistulas: Three Case Reports.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Central Nervous System Vascular Malformations; Cerebral Angi | 2017 |
Proton MR Spectroscopy in Patients With Sleep-Related Hypermotor Epilepsy (SHE): Evidence of Altered Cingulate Cortex Metabolism.
Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Epilepsy; Female; Gyrus Cinguli; Humans; Magne | 2017 |
Cerebral Osmolytes and Plasma Osmolality in Pregnancy and Preeclampsia: A Proton Magnetic Resonance Spectroscopy Study.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Cerebrovascular Circulation; Choline; Creatine; | 2018 |
Treatment outcome of creatine transporter deficiency: international retrospective cohort study.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Creatine; Creatinine; Female; Genotype; Glycin | 2018 |
Treatment outcome of twenty-two patients with guanidinoacetate methyltransferase deficiency: An international retrospective cohort study.
Topics: Cohort Studies; Creatine; Diet, Protein-Restricted; Female; Guanidinoacetate N-Methyltransferase; Hu | 2018 |
In Vivo Mapping and Quantification of Creatine Using Chemical Exchange Saturation Transfer Imaging in Rat Models of Epileptic Seizure.
Topics: Animals; Creatine; Disease Models, Animal; Image Processing, Computer-Assisted; Magnetic Resonance S | 2019 |
The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Creatine; Electrophysiological Phenomena; Epile | 2018 |
Biochemical Changes Indicate Developmental Stage in the Hippocampal Formation.
Topics: Age Factors; Animals; Brain; Creatine; Disease Models, Animal; Hippocampus; Male; Pilocarpine; Rats, | 2019 |
A novel SLC6A8 mutation associated with intellectual disabilities in a Chinese family exhibiting creatine transporter deficiency: case report.
Topics: Asian People; Base Sequence; Brain Diseases, Metabolic, Inborn; Child, Preschool; Chromosomes, Human | 2018 |
Delayed creatine supplementation counteracts reduction of GABAergic function and protects against seizures susceptibility after traumatic brain injury in rats.
Topics: Animals; Brain Injuries, Traumatic; Brain Waves; CA3 Region, Hippocampal; Cell Death; Creatine; Epil | 2019 |
The biochemical changes in hippocampal formation occurring in normal and seizure experiencing rats as a result of a ketogenic diet.
Topics: Animals; Creatine; Diet, Ketogenic; Hippocampus; Lipid Metabolism; Male; Phosphates; Proteins; Rats; | 2015 |
Creatine Deficiency Syndrome could be Missed Easily: A Case Report of Guanidinoacetate Methyltransferase Deficiency Presented with Neurodevelopmental Delay, Seizures, and Behavioral Changes, but Normal Structural MRI.
Topics: Child; Child Behavior; Child, Preschool; Creatine; Developmental Disabilities; Guanidinoacetate N-Me | 2016 |
The effect of epileptic seizures on proton MRS visible neurochemical concentrations.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Data Interpretation, Statistical; Dipeptid | 2008 |
Blockade of GABA synthesis only affects neural excitability under activated conditions in rat hippocampal slices.
Topics: 3-Mercaptopropionic Acid; Animals; Chromatography, High Pressure Liquid; Creatine; Electrophysiology | 2008 |
Expanded clinical and molecular spectrum of guanidinoacetate methyltransferase (GAMT) deficiency.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Female; Guanidi | 2009 |
Additive anticonvulsant effects of creatine supplementation and physical exercise against pentylenetetrazol-induced seizures.
Topics: Animals; Anticonvulsants; Convulsants; Creatine; Male; Oxidative Stress; Pentylenetetrazole; Physica | 2009 |
Intracranial EEG power and metabolism in human epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Creatine; Electrodes, Implanted; Electroencephalography; En | 2009 |
Dissociation between neurovegetative signs and subjective symptoms in a case of idiopathic pilomotor seizures.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Electroencephalography; Epilepsy, Complex | 2010 |
Synchrotron radiation Fourier-transform infrared and Raman microspectroscopy study showing an increased frequency of creatine inclusions in the rat hippocampal formation following pilocarpine-induced seizures.
Topics: Animals; Creatine; Fourier Analysis; Hippocampus; Pilocarpine; Rats; Seizures; Spectrum Analysis, Ra | 2012 |
Acute creatine administration improves mitochondrial membrane potential and protects against pentylenetetrazol-induced seizures.
Topics: Animals; Creatine; Humans; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; | 2013 |
1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Fo | 2003 |
Creatine protects against the convulsive behavior and lactate production elicited by the intrastriatal injection of methylmalonate.
Topics: Animals; Behavior, Animal; Corpus Striatum; Creatine; Disease Models, Animal; Dizocilpine Maleate; D | 2003 |
UREMIC TOXICITY CORRELATED WITH UNIDENTIFIED ANIONS.
Topics: Anions; Blood Chemical Analysis; Creatine; Creatinine; Edema; Glomerulonephritis; Ileostomy; Kidney; | 1963 |
BIOCHEMICAL RESPONSE TO 1,1-DIMETHYLHYDRAZINE (UDMH).
Topics: 1,2-Dimethylhydrazine; Amino Acids; Aspartate Aminotransferases; Blood; Brain Chemistry; Creatine; C | 1964 |
ACUTE AND CHRONIC EFFECTS OF THE INSECTICIDE ENDRIN ON RENAL FUNCTION AND RENAL HEMODYNAMICS.
Topics: Adrenalectomy; Animals; Blood Circulation; Bradycardia; Creatine; Creatinine; Dogs; Endrin; Glomerul | 1964 |
Alexander disease with serial MRS and a new mutation in the glial fibrillary acidic protein gene.
Topics: Acidosis, Respiratory; Alexander Disease; Basal Ganglia; Choline; Creatine; Disease Progression; DNA | 2003 |
[Creatinine; creatine and pentetrazol convulsions].
Topics: Creatine; Creatinine; Humans; Seizures | 1950 |
Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats.
Topics: Acute Disease; Aggression; Animals; Anticonvulsants; Creatine; Creatinine; Dietary Supplements; Emot | 2004 |
Chemical shift imaging and localised magnetic resonance spectroscopy in full-term asphyxiated neonates.
Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Brain; Choline; Creatine; Electroencephalography; F | 2005 |
Effectiveness of creatine monohydrate on seizures and oxidative damage induced by methylmalonate.
Topics: Animals; Behavior, Animal; Creatine; Dizocilpine Maleate; Electrodes, Implanted; Electroencephalogra | 2006 |
1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG.
Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Choline; Creatine; Dipeptides; Electroencephalograp | 2007 |
Decrease of NAA with aging outside the seizure focus in mesial temporal lobe epilepsy--a proton-MRS study at 3 Tesla.
Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Drug Resistance; Epilepsy, Temporal Lobe | 2007 |
Creatine decreases convulsions and neurochemical alterations induced by glutaric acid in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Creatine; Disease | 2007 |
Functional, metabolic, and circulatory changes associated with seizure activity in the postischemic brain.
Topics: Animals; Bicuculline; Cerebrovascular Circulation; Creatine; Energy Metabolism; Glucose; Glycogen; I | 1994 |
In vivo brain phosphocreatine and ATP regulation in mice fed a creatine analog.
Topics: Adenosine Triphosphate; Animals; Brain; Creatine; Creatine Kinase; Diet; Female; Guanidines; Hypoxia | 1997 |
MRS metabolic markers of seizures and seizure-induced neuronal damage.
Topics: Animals; Aspartic Acid; Biomarkers; Brain; Cell Count; Choline; Creatine; Cycloheximide; Hippocampus | 1998 |
Creatine increases survival and suppresses seizures in the hypoxic immature rat.
Topics: Animals; Creatine; Humans; Hypoxia; Rats; Seizures; Survival Analysis | 1998 |
In vivo development of brain phosphocreatine in normal and creatine-treated rabbit pups.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Creatine; Electroencephalography; Energy M | 1999 |
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnet | 2002 |
Cerebral metabolic changes during prolonged epileptic seizures in rats.
Topics: Adenine Nucleotides; Amino Acids; Ammonia; Animals; Bicuculline; Biological Transport; Brain; Citric | 1977 |
Cerebral metabolic and circulatory changes in the rat during sustained seizures induced by DL-homocysteine.
Topics: Amino Acids; Ammonia; Animals; Blood Glucose; Brain; Cerebrovascular Circulation; Citric Acid Cycle; | 1979 |
Cerebral energy state in insulin-induced hypoglycemia, related to blood glucose and to EEG.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Glucose; Carb | 1974 |
Cerebral energy metabolism, pH, and blood flow during seizures in the cat.
Topics: Adenosine Triphosphate; Animals; Bicarbonates; Blood Pressure; Carbon Dioxide; Cats; Cerebral Cortex | 1974 |
Suspected neurotoxicity from intravenous penicillin: a patient case.
Topics: Acute Kidney Injury; Ampicillin; Blood Urea Nitrogen; Chronic Disease; Creatine; Diazepam; Gentamici | 1972 |
Regional energy metabolism in the central nervous system of mice during seizures.
Topics: Animals; Brain Stem; Cerebellum; Creatine; Electroshock; Freezing; Mice; Seizures; Spinal Cord; Thal | 1969 |