Page last updated: 2024-08-21

methionine sulfoximine and Seizures

methionine sulfoximine has been researched along with Seizures in 75 studies

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199056 (74.67)18.7374
1990's3 (4.00)18.2507
2000's3 (4.00)29.6817
2010's10 (13.33)24.3611
2020's3 (4.00)2.80

Authors

AuthorsStudies
Albrecht, J; Aldana, BI; Belfiori-Carrasco, LF; Czarnecka, AM; Obara-Michlewska, M; Pawlik, MJ; Popek, MP1
Albrecht, J; Czarnecka, AM; Czuczwar, SJ; Kołodziej, M; Pawlik, M; Podgajna, M; Skowrońska, K; Węgrzynowicz, M1
Acewicz, A; Albrecht, J; Czarnecka, AM; Czuczwar, SJ; Kołodziej, M; Obara-Michlewska, M; Pawlik, MJ; Popek, MP; Wierzba-Bobrowicz, T; Łuszczki, J1
Damisah, EC; Dhaher, R; Eid, T; Gruenbaum, BF; Gruenbaum, SE; Ong, C; Wang, H; Zaveri, HP1
DiNuzzo, M; Giove, F; Mangia, S; Maraviglia, B1
Dhaher, R; Eid, T; Gruenbaum, SE; Lee, TS; Tu, N; Wang, H; Zaveri, HP1
Dhaher, R; Eid, T; Gruenbaum, SE; Lee, TS; Tang, AB; Wang, H; Zaveri, HP1
Eid, T; Lee, TS; Wang, Y; Zaveri, HP1
Cloix, JF; Hévor, T; Martin, B; Tahi, Z1
Boissonnet, A; Cloix, JF; Hévor, T; Tahi, Z1
Khanam, R; Pal, SN; Pillai, KK; Vohora, D1
Boissonnet, A; Cloix, JF; Hévor, T1
Chen, Z; Fan, YY; Fang, Q; He, P; Hu, WW; Ohtsu, H; Xu, TL; Xu, ZH; Yan, HJ; Yang, Y; Zhang, CY; Zhang, XN; Zhong, K1
Boissonnet, A; Cloix, JF; Hévor, T; Landemarre, L1
Gershoff, SN1
COY, MA; HICKS, SP1
SATO, H1
FOLBERGROVA, J3
HARRIS, B1
GOLDRING, S; JOHNSON, WL; O'LEARY, JL1
TAN, M1
PETERS, EL; TOWER, DB1
Alberici, M; De Robertis, E; Sellinger, OZ; Zieher, LM1
Massieu, GH; Ortega, BG; Pasantes, H; Pérez de la Mora, M; Tapia, R1
Berry, K; Ikeda, H; Wada, JA1
Gregor, P; Schatz, RA; Sellinger, OZ; Tatter, SB; Wilens, TE1
Balkoski, V; Blizard, DA1
Balogh, I; Szegedy, L1
Folbergrova, J; Katsura, KI; Siesjo, BK1
Bot, AP; Corner, MA1
Ardourel, M; Bernard-Helary, K; Cloix, JF; Hévor, T; Lapouble, E1
Ardourel, MY; Bernard-Hélary, K; Cloix, JF; Hévor, T1
McQueen, JK; Woodbury, DM1
Hindfelt, B; Plum, F1
Chin, L; Consroe, P; Picchioni, A1
Gutierrez, JA; Norenberg, MD2
Szegedy, L1
Frye, K; Schatz, RA; Sellinger, OZ1
Javid, MJ; Stone, WE1
Balogh, I; Sótonyi, P; Szegedy, L1
Berel, A; Gayet, J; Lehr, PR1
Horton, RW; Meldrum, BS1
Hamilton, H; Iles, JF1
Engelsen, BA; Fonnum, F; Furset, K1
Alkana, RL; Finn, DA; Jones, BL; Kobayashi, LS; Syapin, PJ1
Jessy, J; Murthy, CR1
Schatz, RA; Toussi, HR; Waszczak, BL1
Goping, G; Klatzo, I; Nitsch, C1
Gill, MW; Schatz, RA1
Gonatas, NK; Rizzuto, N1
Hayashi, T; Taira, M; Takeuchi, H1
Faltin, J; Hartman, J; Lodin, Z; Malanowski, J1
Bazán, NG1
Meister, A; Rowe, WB1
Parker, CM; Smith, GG; Sprince, H1
Kojima, K; Someyama, K; Taira, M; Takeuchi, H1
Brown, DJ; Stone, WE1
Ikeda, H; Wada, J1
Swinyard, EA1
Ikeda, H; Wada, JA2
Asakura, T; Wada, JA1
De Robertis, E1
Ikeda, H; McGeer, EG; Wada, JA1
Jung, E; Terao, A; Wada, JA; White, B1
Lamar, C1
Azcurra, JM; Ohlsson, WG; Sellinger, OZ1
Barlow, CF; Cutler, RW; Lorenzo, AV1
Durbin, RD; Lamar, C; Sinden, SL; Uchytil, TF1
Folbergrová, J; Lowry, OH; Passonneau, JV; Schulz, DW1
Kellaway, P; Proler, ML1
Rucker, GD; Sellinger, OZ1

Reviews

4 review(s) available for methionine sulfoximine and Seizures

ArticleYear
Does abnormal glycogen structure contribute to increased susceptibility to seizures in epilepsy?
    Metabolic brain disease, 2015, Volume: 30, Issue:1

    Topics: Animals; Astrocytes; Convulsants; Disease Susceptibility; Epilepsy; Gliosis; Glucans; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Glycogen; Glycogen Synthase Kinase 3; Homeostasis; Humans; Membrane Potentials; Methionine Sulfoximine; Molecular Structure; Neurons; Potassium; Seizures; Sleep; Sleep Deprivation; Structure-Activity Relationship

2015
Audiogenic seizure susceptible rats.
    Federation proceedings, 1979, Volume: 38, Issue:10

    Topics: Acoustic Stimulation; Aging; Aluminum Hydroxide; Animals; Anticonvulsants; Behavior, Animal; Brain; Catecholamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Methionine Sulfoximine; Pentylenetetrazole; Rats; Reserpine; Seizures; Serotonin; Thiosemicarbazones

1979
Phenomenological and pharmacological identity of audiogenic-sensitive state in animals treated with methionine sulfoximine and in genetically audiogenic-seizure-susceptible animals.
    Recent advances in biological psychiatry, 1966, Volume: 9

    Topics: Animals; Atropine; Cats; Dihydroxyphenylalanine; Electroencephalography; Escape Reaction; Female; Iproniazid; Male; Methionine; Methionine Sulfoximine; Motor Activity; Physostigmine; Rats; Reserpine; Seizures; Serotonin; Sound

1966
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; Electroshock; Humans; Methionine Sulfoximine; Methods; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine; Thiosemicarbazones; Trimethadione; Urea

1969

Other Studies

71 other study(ies) available for methionine sulfoximine and Seizures

ArticleYear
Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose.
    International journal of molecular sciences, 2021, Oct-15, Volume: 22, Issue:20

    Topics: Animals; Brain; Disease Progression; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Lithium; Male; Methionine Sulfoximine; Pilocarpine; Rats; Rats, Sprague-Dawley; Secretory Pathway; Seizures

2021
Attenuation of initial pilocarpine-induced electrographic seizures by methionine sulfoximine pretreatment tightly correlates with the reduction of extracellular taurine in the hippocampus.
    Epilepsia, 2023, Volume: 64, Issue:5

    Topics: Animals; Hippocampus; Methionine Sulfoximine; Pilocarpine; Rats; Seizures; Taurine

2023
Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats.
    Brain research, 2021, 02-15, Volume: 1753

    Topics: Animals; Brain; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Methionine Sulfoximine; Pilocarpine; Rats, Sprague-Dawley; Seizures

2021
5-aminovaleric acid suppresses the development of severe seizures in the methionine sulfoximine model of mesial temporal lobe epilepsy.
    Neurobiology of disease, 2014, Volume: 67

    Topics: Amino Acids, Neutral; Animals; Brain; Disease Models, Animal; Epilepsy, Temporal Lobe; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley; Seizures

2014
Effects of site-specific infusions of methionine sulfoximine on the temporal progression of seizures in a rat model of mesial temporal lobe epilepsy.
    Epilepsy research, 2015, Volume: 115

    Topics: Animals; Astrocytes; Brain; Disease Models, Animal; Disease Progression; Electrocorticography; Epilepsy, Temporal Lobe; Glutamate-Ammonia Ligase; Infusions, Intraventricular; Infusions, Parenteral; Male; Methionine Sulfoximine; Rats, Sprague-Dawley; Seizures; Video Recording

2015
Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy.
    Epilepsy & behavior : E&B, 2015, Volume: 51

    Topics: Amygdala; Analysis of Variance; Anhedonia; Animals; Brain; Central Amygdaloid Nucleus; Comorbidity; Depressive Disorder; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Glutamate-Ammonia Ligase; Hippocampus; Male; Methionine Sulfoximine; Neurons; Rats; Rats, Sprague-Dawley; Seizures

2015
The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic study.
    Experimental neurology, 2009, Volume: 220, Issue:2

    Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Injections; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley; Seizures; Stereotaxic Techniques; Terminology as Topic

2009
Selection of two lines of mice based on latency to onset of methionine sulfoximine seizures.
    Epilepsia, 2010, Volume: 51, Issue:1

    Topics: Animals; Cerebral Cortex; Convulsants; Crosses, Genetic; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Female; Kainic Acid; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pentylenetetrazole; Reaction Time; Seizures; Selection, Genetic

2010
Brain glycogen and neurotransmitter levels in fast and slow methionine sulfoximine-selected mice.
    Experimental neurology, 2010, Volume: 225, Issue:2

    Topics: Analysis of Variance; Animals; Biogenic Monoamines; Brain; Glycogen; Methionine Sulfoximine; Mice; Seizures; Synaptic Transmission; Time Factors

2010
Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice.
    Indian journal of experimental biology, 2010, Volume: 48, Issue:8

    Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Male; Methionine Sulfoximine; Mice; Piperidines; Seizures; Valproic Acid

2010
Phenotypic differences between fast and slow methionine sulfoximine-inbred mice: seizures, anxiety, and glutamine synthetase.
    Epilepsy research, 2012, Volume: 98, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Brain; Female; Glutamate-Ammonia Ligase; Male; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Seizures

2012
Chronic h1-antihistamine treatment increases seizure susceptibility after withdrawal by impairing glutamine synthetase.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:8

    Topics: Animals; Astrocytes; Blotting, Western; Chromatography, High Pressure Liquid; Convulsants; Electroshock; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Histamine H1 Antagonists; Histidine Decarboxylase; Immunohistochemistry; Kindling, Neurologic; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Substance Withdrawal Syndrome

2012
Monoamines and glycogen levels in cerebral cortices of fast and slow methionine sulfoximine-inbred mice.
    Epilepsy research, 2013, Volume: 104, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Disease Models, Animal; Glycogen; Hydroxyindoleacetic Acid; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Seizures; Serotonin; Thiophenes

2013
Biological effects of methionine sulfoximine. II. Comparative sulfur metabolism studies in rats and rabbits.
    The American journal of physiology, 1956, Volume: 184, Issue:1

    Topics: Animals; Biochemical Phenomena; Methionine Sulfoximine; Rabbits; Rats; Research; Seizures; Sulfur

1956
Pathologic effects of antimetabolites. II. Convulsions and brain lesions caused by methionine sulfoximine, and their variation with genotype.
    A.M.A. archives of pathology, 1958, Volume: 65, Issue:4

    Topics: Antimetabolites; Brain; Genotype; Methionine; Methionine Sulfoximine; Seizures

1958
[RESEARCH FOR BEHAVIORAL AND ELECTROENCEPHALOGRAPHICAL CHANGES IN THE EXPERIMENTAL EPILEPSY INDUCED WITH METHIONINE SULFOXIMINE. (A STUDY OF THE EXPERIMENTAL EPILEPSY INDUCED WITH METHIONINE SULFOXIMINE. 1].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1963, Volume: 65

    Topics: Electroencephalography; Epilepsy; Injections; Injections, Intravenous; Methionine; Methionine Sulfoximine; Rabbits; Research; Seizures; Toxicology

1963
FREE GLUTAMINE LEVEL IN THE RAT BRAIN IN VIVO AFTER METHIONINE SULPHOXIMINE ADMINISTRATION.
    Physiologia bohemoslovenica, 1964, Volume: 13

    Topics: Cerebellum; Cerebral Cortex; Diencephalon; Glutamine; Mesencephalon; Methionine; Methionine Sulfoximine; Neurochemistry; Pharmacology; Rats; Research; Seizures; Succinimides; Telencephalon; Toxicology

1964
CORTICAL ALTERATIONS DUE TO METHIONINE SULFOXIMINE. ULTRASTRUCTURE DURING SEIZURE ACTIVITY.
    Archives of neurology, 1964, Volume: 11

    Topics: Animals; Antimetabolites; Cerebral Cortex; Dogs; Electrons; Methionine; Methionine Sulfoximine; Microscopy; Microscopy, Electron; Pathology; Rabbits; Research; Seizures; Toxicology

1964
BEHAVIORAL, UNIT AND SLOW POTENTIAL CHANGES IN METHIONINE SULFOXIMINE SEIZURES.
    Electroencephalography and clinical neurophysiology, 1965, Volume: 18

    Topics: Behavior, Animal; Brain; Cerebral Cortex; Electroencephalography; Electrophysiology; Methionine; Methionine Sulfoximine; Occipital Lobe; Pharmacology; Rabbits; Research; Seizures; Temporal Lobe; Toxicology

1965
[A STUDY OF FREE AMINO ACID METABOLISM IN THE BRAIN TISSUE UNDERLYING METHIONINE SULFOXIMINE SEIZURE--A STUDY OF THE EXPERIMENTAL EPILEPSY INDUCED WITH METHIONINE SULFOXIMINE. 2].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1964, Volume: 66

    Topics: Amino Acids; Brain; Brain Chemistry; Epilepsy; Methionine; Methionine Sulfoximine; Pharmacology; Rabbits; Rats; Research; Seizures; Toxicology

1964
Glutamic acid and glutamine metabolism in cerebral cortex after seizures induced by methionine sulphoximine.
    Journal of neurochemistry, 1959, Volume: 5

    Topics: Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Methionine; Methionine Sulfoximine; Seizures

1959
Nerve endings in methionine sulphoximine convulsant rats, a neurochemical and ultrastructural study.
    Journal of neurochemistry, 1967, Volume: 14, Issue:1

    Topics: Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Cerebral Cortex; Histocytochemistry; In Vitro Techniques; Ligases; Methionine; Methionine Sulfoximine; Microscopy, Electron; Mitochondria; Nerve Endings; Oxidoreductases; Rats; Seizures; Synapses; Transaminases

1967
Free amino acids and glutamate decarboxylase activity in brain of mice during drug-induced convulsions.
    Biochemical pharmacology, 1967, Volume: 16, Issue:3

    Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carboxy-Lyases; Glutamates; Glutamine; Hydrazines; Insulin; Methionine; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Thiosemicarbazones; Transaminases

1967
Reversible behavioral and electrographic manifestations induced by methionine sulfoximine.
    Neurology, 1967, Volume: 17, Issue:9

    Topics: Animals; Arousal; Behavior, Animal; Body Temperature; Brain; Cats; Electroencephalography; Female; Male; Methionine; Methionine Sulfoximine; Movement; Rats; Seizures

1967
Possible role of increased brain methylation in methionine sulfoximine epileptogenesis: effects of administration of adenosine and homocysteine thiolactone.
    Journal of neuroscience research, 1983, Volume: 10, Issue:4

    Topics: Adenosine; Animals; Brain; Brain Chemistry; Histamine; Homocysteine; Methionine Sulfoximine; Methylation; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phospholipids; Reaction Time; Seizures

1983
Tryptophan availability, central serotonergic function and methionine sulphoximine-induced convulsions.
    Neuropharmacology, 1982, Volume: 21, Issue:1

    Topics: Animals; Brain; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Seizures; Serotonin; Time Factors; Tryptophan

1982
Topographical patterns of ultrastructural changes in the rat brain during methionine sulphoximine convulsions.
    Acta morphologica Academiae Scientiarum Hungaricae, 1982, Volume: 30, Issue:2

    Topics: Animals; Brain; Brain Stem; Cerebellar Cortex; Cerebral Cortex; Hippocampus; Methionine Sulfoximine; Rats; Seizures

1982
Glycogen accumulated in the brain following insults is not degraded during a subsequent period of ischemia.
    Journal of the neurological sciences, 1996, Volume: 137, Issue:1

    Topics: Acidosis; Animals; Astrocytes; Brain; Brain Ischemia; Coma; Energy Metabolism; Glycogen; Hypoglycemia; Ischemic Attack, Transient; Male; Methionine Sulfoximine; Phosphorylation; Rats; Rats, Wistar; Reperfusion Injury; Seizures

1996
Cerebral seizure susceptibility and patterns of paroxysmal activity during embryonic development in the domestic chicken.
    Israel journal of medical sciences, 1973, Volume: 9 Suppl

    Topics: Animals; Anticonvulsants; Chick Embryo; Convulsants; Electroencephalography; Glutamic Acid; Methionine Sulfoximine; Ouabain; Pentylenetetrazole; Phenytoin; Seizures

1973
Correlation between brain glycogen and convulsive state in mice submitted to methionine sulfoximine.
    Life sciences, 2000, Aug-25, Volume: 67, Issue:14

    Topics: Animals; Brain; Convulsants; Crosses, Genetic; Female; Genetic Predisposition to Disease; Glucose; Glycogen; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Seizures

2000
In vivo and in vitro glycogenic effects of methionine sulfoximine are different in two inbred strains of mice.
    Brain research, 2002, Mar-08, Volume: 929, Issue:2

    Topics: Animals; Astrocytes; Cells, Cultured; Convulsants; Dose-Response Relationship, Drug; Fructose-Bisphosphatase; Gluconeogenesis; Glycogen; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Osmolar Concentration; RNA, Messenger; Seizures; Species Specificity; Time Factors

2002
Attempts to produce spike-and-wave complexes in the electrocorticogram of the rat.
    Epilepsia, 1975, Volume: 16, Issue:2

    Topics: Animals; Cerebral Cortex; Cobalt; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Estrogens, Conjugated (USP); Fluoroacetates; Male; Methionine Sulfoximine; Pentylenetetrazole; Picrotoxin; Rats; Seizures

1975
L-methionine DL-sulphoximine and acute ammonia toxicity.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:6

    Topics: Acid-Base Equilibrium; Ammonium Chloride; Animals; Blood Pressure; Body Temperature; Lethal Dose 50; Male; Methionine Sulfoximine; Rats; Seizures; Time Factors

1975
Ultrastructural study of methionine sulfoximine-induced Alzheimer type II astrocytosis.
    The American journal of pathology, 1977, Volume: 86, Issue:2

    Topics: Alzheimer Disease; Animals; Astrocytes; Cerebral Cortex; Dementia; Endoplasmic Reticulum; Humans; Male; Methionine Sulfoximine; Mitochondria; Neuroglia; Rats; Seizures; Vacuoles

1977
Enzyme histochemical studies in the rat hippocampus, cerebellar cortex and brainstem motor nuclei during methionine sulphoximine convulsions.
    Cellular and molecular biology, including cyto-enzymology, 1978, Volume: 23, Issue:1

    Topics: Animals; Brain; Brain Stem; Carbohydrate Metabolism; Cerebellar Cortex; Hippocampus; Male; Methionine Sulfoximine; Rats; Seizures

1978
Increased in vivo methylation of [3H]histamine in the methionine sulfoximine epileptogenic mouse brain.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:3

    Topics: Animals; Brain; Deamination; Histamine; Histidine; Histidine Decarboxylase; Male; Methionine Sulfoximine; Methylation; Mice; Seizures; Tranylcypromine

1978
Effects of prior administration of methionine sulfoximine on the thresholds of seizures induced in mice by 3-mercaptopropionic acid or pentylenetetrazol.
    Biochemical pharmacology, 1978, Volume: 27, Issue:24

    Topics: 3-Mercaptopropionic Acid; Animals; Drug Synergism; Glutamate Decarboxylase; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Sulfhydryl Compounds

1978
Ultrastructural changes in the rat cerebellar cortex during methionine sulphoximine convulsions.
    Acta morphologica Academiae Scientiarum Hungaricae, 1978, Volume: 26, Issue:1

    Topics: Animals; Cerebellum; Histocytochemistry; Male; Methionine Sulfoximine; Purkinje Fibers; Rats; Seizures; Succinate Dehydrogenase

1978
Inhibition by metyrapone of convulsions and storage of brain glycogen in mice induced by methionine sulfoximine (MSO).
    Brain research, 1977, Jun-03, Volume: 128, Issue:1

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Glycogen; Male; Methionine Sulfoximine; Metyrapone; Mice; Seizures

1977
Preconvulsive changes in brain glucose metabolism following drugs inhibiting glutamate decarboxylase.
    Journal of neurochemistry, 1976, Volume: 26, Issue:4

    Topics: Animals; Blood Glucose; Body Temperature; Brain; Carboxy-Lyases; Glucose; Glutamate Decarboxylase; Glycine; Glycogen; Isoniazid; Male; Methionine Sulfoximine; Mice; Pyridoxine; Seizures; Time Factors

1976
Alzheimer II astrocytosis following methionine sulfoximine.
    Archives of neurology, 1975, Volume: 32, Issue:2

    Topics: Alzheimer Disease; Animals; Astrocytes; Cell Count; Cell Nucleus; Cerebral Cortex; Dementia; Humans; Male; Methionine Sulfoximine; Neuroglia; Rats; Seizures

1975
Effects of glutamate and sulphur containing amino acids on ammonia toxicity and methionine sulphoximine convulsions in mice.
    Brain research, 1976, Jun-18, Volume: 109, Issue:3

    Topics: Amino Acids, Sulfur; Animals; Anticonvulsants; Arginine; Cystathionine; Cysteic Acid; Glutamates; Homocysteine; Male; Methionine; Methionine Sulfoximine; Mice; Quaternary Ammonium Compounds; Seizures; Taurine

1976
Changes in the levels of glutamate and related amino acids in the intact and decorticated rat neostriatum during various conditions associated with convulsions.
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: 2-Amino-5-phosphonovalerate; Acetates; Amino Acids; Animals; Anticonvulsants; Brain Mapping; Caudate Nucleus; Cerebral Cortex; Cerebral Decortication; Corpus Striatum; Electroencephalography; Epilepsy, Tonic-Clonic; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutaminase; Hypoglycemia; Insulin; Male; Methionine Sulfoximine; Penicillin G; Putamen; Rats; Rats, Wistar; Seizures; Synaptic Transmission

1992
Low-level hyperbaric heliox does not affect drug-induced seizure latency in mice.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Allylglycine; Animals; Atmospheric Pressure; Convulsants; Helium; Hyperbaric Oxygenation; Isoniazid; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Myoclonus; Picrotoxin; Seizures; Time Factors

1991
Branched chain amino acid transaminases in brain in methionine sulphoximine (MSI) toxicity.
    Biochemistry international, 1988, Volume: 16, Issue:2

    Topics: Animals; Brain; Female; Injections, Intraperitoneal; Leucine Transaminase; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Seizures; Transaminases

1988
Suppression of methionine sulfoximine seizures by intranigral gamma-vinyl GABA injection.
    European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3

    Topics: Aminocaproates; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Injections; Male; Methionine Sulfoximine; Rats; Seizures; Substantia Nigra; Vigabatrin

1987
Pathophysiological aspects of blood-brain barrier permeability in epileptic seizures.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Cerebrovascular Circulation; Endothelium; Epilepsy; Kainic Acid; Methionine Sulfoximine; Pentylenetetrazole; Pyridoxine; Rabbits; Seizures

1986
The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 50, Issue:3

    Topics: Animals; Brain Chemistry; Diazepam; Dose-Response Relationship, Drug; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Reaction Time; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures

1985
Ultrastructural study of effect of methionine sulfoximine on developing and adult rat cerebral cortex.
    Journal of neuropathology and experimental neurology, 1974, Volume: 33, Issue:2

    Topics: Animals; Brain; Brain Edema; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Male; Methionine Sulfoximine; Microscopy, Electron; Motor Cortex; Neuroglia; Rats; Seizures; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles

1974
[Comparative study of the convulsion provoking activity of actinomycin D and methionine sulfoximine injected into the cerebrospinal fluid of dogs].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1971, Volume: 165, Issue:6

    Topics: Animals; Brain; Dactinomycin; Dogs; Drug Antagonism; Drug Interactions; Injections, Spinal; Methionine; Methionine Sulfoximine; Seizures

1971
Cytological analysis of the effect of methionine-sulphoximine on cell dimensions and dry mass concentration of cells in the nervous system in vivo.
    Physiologia Bohemoslovaca, 1968, Volume: 17, Issue:5

    Topics: Animals; Cerebellar Cortex; Methionine; Methionine Sulfoximine; Microscopy, Interference; Neuroglia; Neurons; Purkinje Cells; Rabbits; Rats; Seizures; Time Factors

1968
Changes in free fatty acids of brain by drug-induced convulsions, electroshock and anaesthesia.
    Journal of neurochemistry, 1971, Volume: 18, Issue:8

    Topics: Animals; Brain; Cell Membrane; Cyclic AMP; Electroshock; Ethyl Ethers; Fatty Acids, Nonesterified; Hypoxia, Brain; Ischemic Attack, Transient; Lipid Metabolism; Male; Methionine Sulfoximine; Neurons; Pentobarbital; Pentylenetetrazole; Rats; Seizures

1971
Identification of L-methionine-S-sulfoximine as the convulsant isomer of methionine sulfoximine.
    Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 66, Issue:2

    Topics: Animals; Brain; Central Nervous System Stimulants; Ligases; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Seizures; Sheep; Stereoisomerism

1970
3-mercaptopropionic acid: convulsant and lethal properties compared with other sulfur-convulsants; protection therefrom.
    Agents and actions, 1970, Volume: 1, Issue:5

    Topics: Animals; Central Nervous System Stimulants; Glucose; Homocysteine; Lethal Dose 50; Male; Methionine Sulfoximine; Penicillamine; Phenobarbital; Propionates; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Seizures; Sulfhydryl Compounds; Thiosemicarbazones

1970
[Inhibitory effect of gamma aminobutyric acid (GABA) derivatives after intraspinal injection on epileptic convulsions caused by methionine sulfoximine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1972, Volume: 166, Issue:8

    Topics: Aminobutyrates; Animals; Dogs; Female; Male; Methionine Sulfoximine; Seizures; Time Factors

1972
Glycogen and glycogen phosphorylase in the cerebral cortex of mice under the influence of methionine sulphoximine.
    Journal of neurochemistry, 1973, Volume: 20, Issue:2

    Topics: Animals; Brain Chemistry; Cerebral Cortex; Enzyme Activation; Fluorometry; Glucose; Glycogen; In Vitro Techniques; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Phosphorylases; Seizures; Time Factors

1973
Glutamate and aspartate in cortical subarachnoid fluid in relation to convulsive activity.
    Brain research, 1973, May-17, Volume: 54

    Topics: Animals; Aspartic Acid; Azoles; Brain; Dogs; Glutamates; Methionine Sulfoximine; Picrotoxin; Seizures; Subarachnoid Space; Thiosemicarbazones

1973
The susceptibility to auditory stimuli of animals treated with methionine sulfoximine.
    Experimental neurology, 1966, Volume: 15, Issue:2

    Topics: Animals; Auditory Pathways; Behavior, Animal; Cats; Dose-Response Relationship, Drug; Female; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Seizures

1966
Susceptibility to audiogenic seizure induced by thiosemicarbazide.
    Experimental neurology, 1969, Volume: 24, Issue:1

    Topics: Amygdala; Animals; Auditory Cortex; Behavior, Animal; Body Temperature; Cats; Caudate Nucleus; Cerebellar Cortex; Electrophysiology; Haplorhini; Hippocampus; Methionine Sulfoximine; Rats; Reticular Formation; Seizures; Sound; Stimulation, Chemical; Temporal Lobe; Thalamus; Thiosemicarbazones; Visual Cortex; Vomiting

1969
Studies on neurochemical changes in experimental epilepsy.
    Triangle; the Sandoz journal of medical science, 1971, Volume: 10, Issue:3

    Topics: Allyl Compounds; Aminobutyrates; Animals; Biogenic Amines; Brain Chemistry; Carboxy-Lyases; Cerebral Cortex; Disease Models, Animal; Methionine Sulfoximine; Microscopy, Electron; Pentylenetetrazole; Rats; Seizures

1971
The susceptibility to audiogenic stimuli of rats treated with methionine sulfoximine and various psychoactive agents.
    Experimental neurology, 1967, Volume: 18, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Iproniazid; Male; Methionine; Methionine Sulfoximine; Movement; Rats; Reserpine; Seizures; Sound

1967
Inferior colliculus lesion and audiogenic seizure susceptibility.
    Experimental neurology, 1970, Volume: 28, Issue:2

    Topics: Animals; Behavior, Animal; Cats; Female; Functional Laterality; Male; Methionine Sulfoximine; Noise; Pentylenetetrazole; Rats; Seizures; Tectum Mesencephali; Thiosemicarbazones

1970
Mercaptopropionic acid: a convulsant that inhibits glutamate decarboxylase.
    Journal of neurochemistry, 1970, Volume: 17, Issue:2

    Topics: Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Centrifugation; Hydrazines; In Vitro Techniques; Injections, Intraperitoneal; Lactates; Ligases; Male; Methionine Sulfoximine; Propionates; Pseudomonas; Pyridoxal Phosphate; Rats; Seizures; Transaminases

1970
Energy metabolism in the brain during methionine-sulfoximine seizures.
    Rivista di patologia nervosa e mentale, 1970, Volume: 91, Issue:6

    Topics: Adenosine Triphosphate; Animals; Brain; Glucose; Glycogen; Lactates; Methionine; Methionine Sulfoximine; Mice; Phosphocreatine; Seizures

1970
Methionine sulfoximine seizures. 8. The dissociation of the convulsant and glutamine synthetase inhibitory effects.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 164, Issue:1

    Topics: Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Glutamine; Heart Ventricles; Hypothalamus; Injections; Injections, Intraperitoneal; Methionine; Methionine Sulfoximine; Rats; Seizures; Thalamus; Transferases

1968
Changes in blood-brain permeability during pharmacologically induced convulsions.
    Progress in brain research, 1968, Volume: 29

    Topics: Animals; Autoradiography; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; Carbon Dioxide; Cats; Hypercapnia; Methionine Sulfoximine; Oxygen; Partial Pressure; Pentylenetetrazole; Seizures; Serum Albumin, Radio-Iodinated; Strychnine; Sulfates; Sulfur Isotopes

1968
The production of convulsions by an exotoxin from Pseudomonas tabaci.
    Toxicology and applied pharmacology, 1969, Volume: 14, Issue:1

    Topics: Animals; Methionine; Methionine Sulfoximine; Mice; Nicotiana; Plants, Toxic; Pseudomonas; Rats; Seizures; Toxins, Biological

1969
Glycogen, ammonia and related metabolities in the brain during seizures evoked by methionine sulphoximine.
    Journal of neurochemistry, 1969, Volume: 16, Issue:2

    Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Cerebellum; Cerebral Cortex; Glucose; Glutamates; Glycogen; Lactates; Male; Methionine Sulfoximine; Methods; Phosphocreatine; Rats; Seizures; Time Factors

1969
Behavioral and convulsive phenomena induced in the cat by methionine sulfoximine. Ablation and electrographic studies.
    Neurology, 1965, Volume: 15, Issue:10

    Topics: Animals; Behavior, Animal; Brain Diseases; Cats; Electroencephalography; Methionine; Methionine Sulfoximine; Seizures

1965
Cerebral lysosomes. 3. Evidence for in vivo "labilization" by the convulsant DL-methionine-DL-sulfoximine.
    Life sciences, 1966, Volume: 5, Issue:2

    Topics: Acid Phosphatase; Animals; Brain; Glycoside Hydrolases; In Vitro Techniques; Lysosomes; Methionine; Methionine Sulfoximine; Rats; Seizures

1966
Effect of atropine and eserine on the episodic behavioral and electrographic manifestations induced by methionine sulfoximine.
    Experimental neurology, 1966, Volume: 16, Issue:4

    Topics: Animals; Atropine; Behavior, Animal; Cats; Electroencephalography; Fear; Methionine; Methionine Sulfoximine; Physostigmine; Rats; Seizures; Sound

1966