methionine sulfoximine has been researched along with Seizures in 75 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 56 (74.67) | 18.7374 |
1990's | 3 (4.00) | 18.2507 |
2000's | 3 (4.00) | 29.6817 |
2010's | 10 (13.33) | 24.3611 |
2020's | 3 (4.00) | 2.80 |
Authors | Studies |
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Albrecht, J; Aldana, BI; Belfiori-Carrasco, LF; Czarnecka, AM; Obara-Michlewska, M; Pawlik, MJ; Popek, MP | 1 |
Albrecht, J; Czarnecka, AM; Czuczwar, SJ; Kołodziej, M; Pawlik, M; Podgajna, M; Skowrońska, K; Węgrzynowicz, M | 1 |
Acewicz, A; Albrecht, J; Czarnecka, AM; Czuczwar, SJ; Kołodziej, M; Obara-Michlewska, M; Pawlik, MJ; Popek, MP; Wierzba-Bobrowicz, T; Łuszczki, J | 1 |
Damisah, EC; Dhaher, R; Eid, T; Gruenbaum, BF; Gruenbaum, SE; Ong, C; Wang, H; Zaveri, HP | 1 |
DiNuzzo, M; Giove, F; Mangia, S; Maraviglia, B | 1 |
Dhaher, R; Eid, T; Gruenbaum, SE; Lee, TS; Tu, N; Wang, H; Zaveri, HP | 1 |
Dhaher, R; Eid, T; Gruenbaum, SE; Lee, TS; Tang, AB; Wang, H; Zaveri, HP | 1 |
Eid, T; Lee, TS; Wang, Y; Zaveri, HP | 1 |
Cloix, JF; Hévor, T; Martin, B; Tahi, Z | 1 |
Boissonnet, A; Cloix, JF; Hévor, T; Tahi, Z | 1 |
Khanam, R; Pal, SN; Pillai, KK; Vohora, D | 1 |
Boissonnet, A; Cloix, JF; Hévor, T | 1 |
Chen, Z; Fan, YY; Fang, Q; He, P; Hu, WW; Ohtsu, H; Xu, TL; Xu, ZH; Yan, HJ; Yang, Y; Zhang, CY; Zhang, XN; Zhong, K | 1 |
Boissonnet, A; Cloix, JF; Hévor, T; Landemarre, L | 1 |
Gershoff, SN | 1 |
COY, MA; HICKS, SP | 1 |
SATO, H | 1 |
FOLBERGROVA, J | 3 |
HARRIS, B | 1 |
GOLDRING, S; JOHNSON, WL; O'LEARY, JL | 1 |
TAN, M | 1 |
PETERS, EL; TOWER, DB | 1 |
Alberici, M; De Robertis, E; Sellinger, OZ; Zieher, LM | 1 |
Massieu, GH; Ortega, BG; Pasantes, H; Pérez de la Mora, M; Tapia, R | 1 |
Berry, K; Ikeda, H; Wada, JA | 1 |
Gregor, P; Schatz, RA; Sellinger, OZ; Tatter, SB; Wilens, TE | 1 |
Balkoski, V; Blizard, DA | 1 |
Balogh, I; Szegedy, L | 1 |
Folbergrova, J; Katsura, KI; Siesjo, BK | 1 |
Bot, AP; Corner, MA | 1 |
Ardourel, M; Bernard-Helary, K; Cloix, JF; Hévor, T; Lapouble, E | 1 |
Ardourel, MY; Bernard-Hélary, K; Cloix, JF; Hévor, T | 1 |
McQueen, JK; Woodbury, DM | 1 |
Hindfelt, B; Plum, F | 1 |
Chin, L; Consroe, P; Picchioni, A | 1 |
Gutierrez, JA; Norenberg, MD | 2 |
Szegedy, L | 1 |
Frye, K; Schatz, RA; Sellinger, OZ | 1 |
Javid, MJ; Stone, WE | 1 |
Balogh, I; Sótonyi, P; Szegedy, L | 1 |
Berel, A; Gayet, J; Lehr, PR | 1 |
Horton, RW; Meldrum, BS | 1 |
Hamilton, H; Iles, JF | 1 |
Engelsen, BA; Fonnum, F; Furset, K | 1 |
Alkana, RL; Finn, DA; Jones, BL; Kobayashi, LS; Syapin, PJ | 1 |
Jessy, J; Murthy, CR | 1 |
Schatz, RA; Toussi, HR; Waszczak, BL | 1 |
Goping, G; Klatzo, I; Nitsch, C | 1 |
Gill, MW; Schatz, RA | 1 |
Gonatas, NK; Rizzuto, N | 1 |
Hayashi, T; Taira, M; Takeuchi, H | 1 |
Faltin, J; Hartman, J; Lodin, Z; Malanowski, J | 1 |
Bazán, NG | 1 |
Meister, A; Rowe, WB | 1 |
Parker, CM; Smith, GG; Sprince, H | 1 |
Kojima, K; Someyama, K; Taira, M; Takeuchi, H | 1 |
Brown, DJ; Stone, WE | 1 |
Ikeda, H; Wada, J | 1 |
Swinyard, EA | 1 |
Ikeda, H; Wada, JA | 2 |
Asakura, T; Wada, JA | 1 |
De Robertis, E | 1 |
Ikeda, H; McGeer, EG; Wada, JA | 1 |
Jung, E; Terao, A; Wada, JA; White, B | 1 |
Lamar, C | 1 |
Azcurra, JM; Ohlsson, WG; Sellinger, OZ | 1 |
Barlow, CF; Cutler, RW; Lorenzo, AV | 1 |
Durbin, RD; Lamar, C; Sinden, SL; Uchytil, TF | 1 |
Folbergrová, J; Lowry, OH; Passonneau, JV; Schulz, DW | 1 |
Kellaway, P; Proler, ML | 1 |
Rucker, GD; Sellinger, OZ | 1 |
4 review(s) available for methionine sulfoximine and Seizures
Article | Year |
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Does abnormal glycogen structure contribute to increased susceptibility to seizures in epilepsy?
Topics: Animals; Astrocytes; Convulsants; Disease Susceptibility; Epilepsy; Gliosis; Glucans; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Glycogen; Glycogen Synthase Kinase 3; Homeostasis; Humans; Membrane Potentials; Methionine Sulfoximine; Molecular Structure; Neurons; Potassium; Seizures; Sleep; Sleep Deprivation; Structure-Activity Relationship | 2015 |
Audiogenic seizure susceptible rats.
Topics: Acoustic Stimulation; Aging; Aluminum Hydroxide; Animals; Anticonvulsants; Behavior, Animal; Brain; Catecholamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Methionine Sulfoximine; Pentylenetetrazole; Rats; Reserpine; Seizures; Serotonin; Thiosemicarbazones | 1979 |
Phenomenological and pharmacological identity of audiogenic-sensitive state in animals treated with methionine sulfoximine and in genetically audiogenic-seizure-susceptible animals.
Topics: Animals; Atropine; Cats; Dihydroxyphenylalanine; Electroencephalography; Escape Reaction; Female; Iproniazid; Male; Methionine; Methionine Sulfoximine; Motor Activity; Physostigmine; Rats; Reserpine; Seizures; Serotonin; Sound | 1966 |
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods.
Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; Electroshock; Humans; Methionine Sulfoximine; Methods; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine; Thiosemicarbazones; Trimethadione; Urea | 1969 |
71 other study(ies) available for methionine sulfoximine and Seizures
Article | Year |
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Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose.
Topics: Animals; Brain; Disease Progression; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Lithium; Male; Methionine Sulfoximine; Pilocarpine; Rats; Rats, Sprague-Dawley; Secretory Pathway; Seizures | 2021 |
Attenuation of initial pilocarpine-induced electrographic seizures by methionine sulfoximine pretreatment tightly correlates with the reduction of extracellular taurine in the hippocampus.
Topics: Animals; Hippocampus; Methionine Sulfoximine; Pilocarpine; Rats; Seizures; Taurine | 2023 |
Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats.
Topics: Animals; Brain; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Methionine Sulfoximine; Pilocarpine; Rats, Sprague-Dawley; Seizures | 2021 |
5-aminovaleric acid suppresses the development of severe seizures in the methionine sulfoximine model of mesial temporal lobe epilepsy.
Topics: Amino Acids, Neutral; Animals; Brain; Disease Models, Animal; Epilepsy, Temporal Lobe; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley; Seizures | 2014 |
Effects of site-specific infusions of methionine sulfoximine on the temporal progression of seizures in a rat model of mesial temporal lobe epilepsy.
Topics: Animals; Astrocytes; Brain; Disease Models, Animal; Disease Progression; Electrocorticography; Epilepsy, Temporal Lobe; Glutamate-Ammonia Ligase; Infusions, Intraventricular; Infusions, Parenteral; Male; Methionine Sulfoximine; Rats, Sprague-Dawley; Seizures; Video Recording | 2015 |
Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy.
Topics: Amygdala; Analysis of Variance; Anhedonia; Animals; Brain; Central Amygdaloid Nucleus; Comorbidity; Depressive Disorder; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Glutamate-Ammonia Ligase; Hippocampus; Male; Methionine Sulfoximine; Neurons; Rats; Rats, Sprague-Dawley; Seizures | 2015 |
The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic study.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Injections; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley; Seizures; Stereotaxic Techniques; Terminology as Topic | 2009 |
Selection of two lines of mice based on latency to onset of methionine sulfoximine seizures.
Topics: Animals; Cerebral Cortex; Convulsants; Crosses, Genetic; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Female; Kainic Acid; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pentylenetetrazole; Reaction Time; Seizures; Selection, Genetic | 2010 |
Brain glycogen and neurotransmitter levels in fast and slow methionine sulfoximine-selected mice.
Topics: Analysis of Variance; Animals; Biogenic Monoamines; Brain; Glycogen; Methionine Sulfoximine; Mice; Seizures; Synaptic Transmission; Time Factors | 2010 |
Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice.
Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Male; Methionine Sulfoximine; Mice; Piperidines; Seizures; Valproic Acid | 2010 |
Phenotypic differences between fast and slow methionine sulfoximine-inbred mice: seizures, anxiety, and glutamine synthetase.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Female; Glutamate-Ammonia Ligase; Male; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Seizures | 2012 |
Chronic h1-antihistamine treatment increases seizure susceptibility after withdrawal by impairing glutamine synthetase.
Topics: Animals; Astrocytes; Blotting, Western; Chromatography, High Pressure Liquid; Convulsants; Electroshock; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Histamine H1 Antagonists; Histidine Decarboxylase; Immunohistochemistry; Kindling, Neurologic; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Substance Withdrawal Syndrome | 2012 |
Monoamines and glycogen levels in cerebral cortices of fast and slow methionine sulfoximine-inbred mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Disease Models, Animal; Glycogen; Hydroxyindoleacetic Acid; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Seizures; Serotonin; Thiophenes | 2013 |
Biological effects of methionine sulfoximine. II. Comparative sulfur metabolism studies in rats and rabbits.
Topics: Animals; Biochemical Phenomena; Methionine Sulfoximine; Rabbits; Rats; Research; Seizures; Sulfur | 1956 |
Pathologic effects of antimetabolites. II. Convulsions and brain lesions caused by methionine sulfoximine, and their variation with genotype.
Topics: Antimetabolites; Brain; Genotype; Methionine; Methionine Sulfoximine; Seizures | 1958 |
[RESEARCH FOR BEHAVIORAL AND ELECTROENCEPHALOGRAPHICAL CHANGES IN THE EXPERIMENTAL EPILEPSY INDUCED WITH METHIONINE SULFOXIMINE. (A STUDY OF THE EXPERIMENTAL EPILEPSY INDUCED WITH METHIONINE SULFOXIMINE. 1].
Topics: Electroencephalography; Epilepsy; Injections; Injections, Intravenous; Methionine; Methionine Sulfoximine; Rabbits; Research; Seizures; Toxicology | 1963 |
FREE GLUTAMINE LEVEL IN THE RAT BRAIN IN VIVO AFTER METHIONINE SULPHOXIMINE ADMINISTRATION.
Topics: Cerebellum; Cerebral Cortex; Diencephalon; Glutamine; Mesencephalon; Methionine; Methionine Sulfoximine; Neurochemistry; Pharmacology; Rats; Research; Seizures; Succinimides; Telencephalon; Toxicology | 1964 |
CORTICAL ALTERATIONS DUE TO METHIONINE SULFOXIMINE. ULTRASTRUCTURE DURING SEIZURE ACTIVITY.
Topics: Animals; Antimetabolites; Cerebral Cortex; Dogs; Electrons; Methionine; Methionine Sulfoximine; Microscopy; Microscopy, Electron; Pathology; Rabbits; Research; Seizures; Toxicology | 1964 |
BEHAVIORAL, UNIT AND SLOW POTENTIAL CHANGES IN METHIONINE SULFOXIMINE SEIZURES.
Topics: Behavior, Animal; Brain; Cerebral Cortex; Electroencephalography; Electrophysiology; Methionine; Methionine Sulfoximine; Occipital Lobe; Pharmacology; Rabbits; Research; Seizures; Temporal Lobe; Toxicology | 1965 |
[A STUDY OF FREE AMINO ACID METABOLISM IN THE BRAIN TISSUE UNDERLYING METHIONINE SULFOXIMINE SEIZURE--A STUDY OF THE EXPERIMENTAL EPILEPSY INDUCED WITH METHIONINE SULFOXIMINE. 2].
Topics: Amino Acids; Brain; Brain Chemistry; Epilepsy; Methionine; Methionine Sulfoximine; Pharmacology; Rabbits; Rats; Research; Seizures; Toxicology | 1964 |
Glutamic acid and glutamine metabolism in cerebral cortex after seizures induced by methionine sulphoximine.
Topics: Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Methionine; Methionine Sulfoximine; Seizures | 1959 |
Nerve endings in methionine sulphoximine convulsant rats, a neurochemical and ultrastructural study.
Topics: Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Cerebral Cortex; Histocytochemistry; In Vitro Techniques; Ligases; Methionine; Methionine Sulfoximine; Microscopy, Electron; Mitochondria; Nerve Endings; Oxidoreductases; Rats; Seizures; Synapses; Transaminases | 1967 |
Free amino acids and glutamate decarboxylase activity in brain of mice during drug-induced convulsions.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carboxy-Lyases; Glutamates; Glutamine; Hydrazines; Insulin; Methionine; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Thiosemicarbazones; Transaminases | 1967 |
Reversible behavioral and electrographic manifestations induced by methionine sulfoximine.
Topics: Animals; Arousal; Behavior, Animal; Body Temperature; Brain; Cats; Electroencephalography; Female; Male; Methionine; Methionine Sulfoximine; Movement; Rats; Seizures | 1967 |
Possible role of increased brain methylation in methionine sulfoximine epileptogenesis: effects of administration of adenosine and homocysteine thiolactone.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Histamine; Homocysteine; Methionine Sulfoximine; Methylation; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phospholipids; Reaction Time; Seizures | 1983 |
Tryptophan availability, central serotonergic function and methionine sulphoximine-induced convulsions.
Topics: Animals; Brain; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Seizures; Serotonin; Time Factors; Tryptophan | 1982 |
Topographical patterns of ultrastructural changes in the rat brain during methionine sulphoximine convulsions.
Topics: Animals; Brain; Brain Stem; Cerebellar Cortex; Cerebral Cortex; Hippocampus; Methionine Sulfoximine; Rats; Seizures | 1982 |
Glycogen accumulated in the brain following insults is not degraded during a subsequent period of ischemia.
Topics: Acidosis; Animals; Astrocytes; Brain; Brain Ischemia; Coma; Energy Metabolism; Glycogen; Hypoglycemia; Ischemic Attack, Transient; Male; Methionine Sulfoximine; Phosphorylation; Rats; Rats, Wistar; Reperfusion Injury; Seizures | 1996 |
Cerebral seizure susceptibility and patterns of paroxysmal activity during embryonic development in the domestic chicken.
Topics: Animals; Anticonvulsants; Chick Embryo; Convulsants; Electroencephalography; Glutamic Acid; Methionine Sulfoximine; Ouabain; Pentylenetetrazole; Phenytoin; Seizures | 1973 |
Correlation between brain glycogen and convulsive state in mice submitted to methionine sulfoximine.
Topics: Animals; Brain; Convulsants; Crosses, Genetic; Female; Genetic Predisposition to Disease; Glucose; Glycogen; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Seizures | 2000 |
In vivo and in vitro glycogenic effects of methionine sulfoximine are different in two inbred strains of mice.
Topics: Animals; Astrocytes; Cells, Cultured; Convulsants; Dose-Response Relationship, Drug; Fructose-Bisphosphatase; Gluconeogenesis; Glycogen; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Osmolar Concentration; RNA, Messenger; Seizures; Species Specificity; Time Factors | 2002 |
Attempts to produce spike-and-wave complexes in the electrocorticogram of the rat.
Topics: Animals; Cerebral Cortex; Cobalt; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Estrogens, Conjugated (USP); Fluoroacetates; Male; Methionine Sulfoximine; Pentylenetetrazole; Picrotoxin; Rats; Seizures | 1975 |
L-methionine DL-sulphoximine and acute ammonia toxicity.
Topics: Acid-Base Equilibrium; Ammonium Chloride; Animals; Blood Pressure; Body Temperature; Lethal Dose 50; Male; Methionine Sulfoximine; Rats; Seizures; Time Factors | 1975 |
Ultrastructural study of methionine sulfoximine-induced Alzheimer type II astrocytosis.
Topics: Alzheimer Disease; Animals; Astrocytes; Cerebral Cortex; Dementia; Endoplasmic Reticulum; Humans; Male; Methionine Sulfoximine; Mitochondria; Neuroglia; Rats; Seizures; Vacuoles | 1977 |
Enzyme histochemical studies in the rat hippocampus, cerebellar cortex and brainstem motor nuclei during methionine sulphoximine convulsions.
Topics: Animals; Brain; Brain Stem; Carbohydrate Metabolism; Cerebellar Cortex; Hippocampus; Male; Methionine Sulfoximine; Rats; Seizures | 1978 |
Increased in vivo methylation of [3H]histamine in the methionine sulfoximine epileptogenic mouse brain.
Topics: Animals; Brain; Deamination; Histamine; Histidine; Histidine Decarboxylase; Male; Methionine Sulfoximine; Methylation; Mice; Seizures; Tranylcypromine | 1978 |
Effects of prior administration of methionine sulfoximine on the thresholds of seizures induced in mice by 3-mercaptopropionic acid or pentylenetetrazol.
Topics: 3-Mercaptopropionic Acid; Animals; Drug Synergism; Glutamate Decarboxylase; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Sulfhydryl Compounds | 1978 |
Ultrastructural changes in the rat cerebellar cortex during methionine sulphoximine convulsions.
Topics: Animals; Cerebellum; Histocytochemistry; Male; Methionine Sulfoximine; Purkinje Fibers; Rats; Seizures; Succinate Dehydrogenase | 1978 |
Inhibition by metyrapone of convulsions and storage of brain glycogen in mice induced by methionine sulfoximine (MSO).
Topics: Animals; Brain; Dose-Response Relationship, Drug; Glycogen; Male; Methionine Sulfoximine; Metyrapone; Mice; Seizures | 1977 |
Preconvulsive changes in brain glucose metabolism following drugs inhibiting glutamate decarboxylase.
Topics: Animals; Blood Glucose; Body Temperature; Brain; Carboxy-Lyases; Glucose; Glutamate Decarboxylase; Glycine; Glycogen; Isoniazid; Male; Methionine Sulfoximine; Mice; Pyridoxine; Seizures; Time Factors | 1976 |
Alzheimer II astrocytosis following methionine sulfoximine.
Topics: Alzheimer Disease; Animals; Astrocytes; Cell Count; Cell Nucleus; Cerebral Cortex; Dementia; Humans; Male; Methionine Sulfoximine; Neuroglia; Rats; Seizures | 1975 |
Effects of glutamate and sulphur containing amino acids on ammonia toxicity and methionine sulphoximine convulsions in mice.
Topics: Amino Acids, Sulfur; Animals; Anticonvulsants; Arginine; Cystathionine; Cysteic Acid; Glutamates; Homocysteine; Male; Methionine; Methionine Sulfoximine; Mice; Quaternary Ammonium Compounds; Seizures; Taurine | 1976 |
Changes in the levels of glutamate and related amino acids in the intact and decorticated rat neostriatum during various conditions associated with convulsions.
Topics: 2-Amino-5-phosphonovalerate; Acetates; Amino Acids; Animals; Anticonvulsants; Brain Mapping; Caudate Nucleus; Cerebral Cortex; Cerebral Decortication; Corpus Striatum; Electroencephalography; Epilepsy, Tonic-Clonic; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutaminase; Hypoglycemia; Insulin; Male; Methionine Sulfoximine; Penicillin G; Putamen; Rats; Rats, Wistar; Seizures; Synaptic Transmission | 1992 |
Low-level hyperbaric heliox does not affect drug-induced seizure latency in mice.
Topics: Allylglycine; Animals; Atmospheric Pressure; Convulsants; Helium; Hyperbaric Oxygenation; Isoniazid; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Myoclonus; Picrotoxin; Seizures; Time Factors | 1991 |
Branched chain amino acid transaminases in brain in methionine sulphoximine (MSI) toxicity.
Topics: Animals; Brain; Female; Injections, Intraperitoneal; Leucine Transaminase; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Seizures; Transaminases | 1988 |
Suppression of methionine sulfoximine seizures by intranigral gamma-vinyl GABA injection.
Topics: Aminocaproates; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Injections; Male; Methionine Sulfoximine; Rats; Seizures; Substantia Nigra; Vigabatrin | 1987 |
Pathophysiological aspects of blood-brain barrier permeability in epileptic seizures.
Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Cerebrovascular Circulation; Endothelium; Epilepsy; Kainic Acid; Methionine Sulfoximine; Pentylenetetrazole; Pyridoxine; Rabbits; Seizures | 1986 |
The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
Topics: Animals; Brain Chemistry; Diazepam; Dose-Response Relationship, Drug; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Reaction Time; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures | 1985 |
Ultrastructural study of effect of methionine sulfoximine on developing and adult rat cerebral cortex.
Topics: Animals; Brain; Brain Edema; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Male; Methionine Sulfoximine; Microscopy, Electron; Motor Cortex; Neuroglia; Rats; Seizures; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles | 1974 |
[Comparative study of the convulsion provoking activity of actinomycin D and methionine sulfoximine injected into the cerebrospinal fluid of dogs].
Topics: Animals; Brain; Dactinomycin; Dogs; Drug Antagonism; Drug Interactions; Injections, Spinal; Methionine; Methionine Sulfoximine; Seizures | 1971 |
Cytological analysis of the effect of methionine-sulphoximine on cell dimensions and dry mass concentration of cells in the nervous system in vivo.
Topics: Animals; Cerebellar Cortex; Methionine; Methionine Sulfoximine; Microscopy, Interference; Neuroglia; Neurons; Purkinje Cells; Rabbits; Rats; Seizures; Time Factors | 1968 |
Changes in free fatty acids of brain by drug-induced convulsions, electroshock and anaesthesia.
Topics: Animals; Brain; Cell Membrane; Cyclic AMP; Electroshock; Ethyl Ethers; Fatty Acids, Nonesterified; Hypoxia, Brain; Ischemic Attack, Transient; Lipid Metabolism; Male; Methionine Sulfoximine; Neurons; Pentobarbital; Pentylenetetrazole; Rats; Seizures | 1971 |
Identification of L-methionine-S-sulfoximine as the convulsant isomer of methionine sulfoximine.
Topics: Animals; Brain; Central Nervous System Stimulants; Ligases; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Seizures; Sheep; Stereoisomerism | 1970 |
3-mercaptopropionic acid: convulsant and lethal properties compared with other sulfur-convulsants; protection therefrom.
Topics: Animals; Central Nervous System Stimulants; Glucose; Homocysteine; Lethal Dose 50; Male; Methionine Sulfoximine; Penicillamine; Phenobarbital; Propionates; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Seizures; Sulfhydryl Compounds; Thiosemicarbazones | 1970 |
[Inhibitory effect of gamma aminobutyric acid (GABA) derivatives after intraspinal injection on epileptic convulsions caused by methionine sulfoximine].
Topics: Aminobutyrates; Animals; Dogs; Female; Male; Methionine Sulfoximine; Seizures; Time Factors | 1972 |
Glycogen and glycogen phosphorylase in the cerebral cortex of mice under the influence of methionine sulphoximine.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Enzyme Activation; Fluorometry; Glucose; Glycogen; In Vitro Techniques; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Phosphorylases; Seizures; Time Factors | 1973 |
Glutamate and aspartate in cortical subarachnoid fluid in relation to convulsive activity.
Topics: Animals; Aspartic Acid; Azoles; Brain; Dogs; Glutamates; Methionine Sulfoximine; Picrotoxin; Seizures; Subarachnoid Space; Thiosemicarbazones | 1973 |
The susceptibility to auditory stimuli of animals treated with methionine sulfoximine.
Topics: Animals; Auditory Pathways; Behavior, Animal; Cats; Dose-Response Relationship, Drug; Female; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Seizures | 1966 |
Susceptibility to audiogenic seizure induced by thiosemicarbazide.
Topics: Amygdala; Animals; Auditory Cortex; Behavior, Animal; Body Temperature; Cats; Caudate Nucleus; Cerebellar Cortex; Electrophysiology; Haplorhini; Hippocampus; Methionine Sulfoximine; Rats; Reticular Formation; Seizures; Sound; Stimulation, Chemical; Temporal Lobe; Thalamus; Thiosemicarbazones; Visual Cortex; Vomiting | 1969 |
Studies on neurochemical changes in experimental epilepsy.
Topics: Allyl Compounds; Aminobutyrates; Animals; Biogenic Amines; Brain Chemistry; Carboxy-Lyases; Cerebral Cortex; Disease Models, Animal; Methionine Sulfoximine; Microscopy, Electron; Pentylenetetrazole; Rats; Seizures | 1971 |
The susceptibility to audiogenic stimuli of rats treated with methionine sulfoximine and various psychoactive agents.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Iproniazid; Male; Methionine; Methionine Sulfoximine; Movement; Rats; Reserpine; Seizures; Sound | 1967 |
Inferior colliculus lesion and audiogenic seizure susceptibility.
Topics: Animals; Behavior, Animal; Cats; Female; Functional Laterality; Male; Methionine Sulfoximine; Noise; Pentylenetetrazole; Rats; Seizures; Tectum Mesencephali; Thiosemicarbazones | 1970 |
Mercaptopropionic acid: a convulsant that inhibits glutamate decarboxylase.
Topics: Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Centrifugation; Hydrazines; In Vitro Techniques; Injections, Intraperitoneal; Lactates; Ligases; Male; Methionine Sulfoximine; Propionates; Pseudomonas; Pyridoxal Phosphate; Rats; Seizures; Transaminases | 1970 |
Energy metabolism in the brain during methionine-sulfoximine seizures.
Topics: Adenosine Triphosphate; Animals; Brain; Glucose; Glycogen; Lactates; Methionine; Methionine Sulfoximine; Mice; Phosphocreatine; Seizures | 1970 |
Methionine sulfoximine seizures. 8. The dissociation of the convulsant and glutamine synthetase inhibitory effects.
Topics: Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Glutamine; Heart Ventricles; Hypothalamus; Injections; Injections, Intraperitoneal; Methionine; Methionine Sulfoximine; Rats; Seizures; Thalamus; Transferases | 1968 |
Changes in blood-brain permeability during pharmacologically induced convulsions.
Topics: Animals; Autoradiography; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; Carbon Dioxide; Cats; Hypercapnia; Methionine Sulfoximine; Oxygen; Partial Pressure; Pentylenetetrazole; Seizures; Serum Albumin, Radio-Iodinated; Strychnine; Sulfates; Sulfur Isotopes | 1968 |
The production of convulsions by an exotoxin from Pseudomonas tabaci.
Topics: Animals; Methionine; Methionine Sulfoximine; Mice; Nicotiana; Plants, Toxic; Pseudomonas; Rats; Seizures; Toxins, Biological | 1969 |
Glycogen, ammonia and related metabolities in the brain during seizures evoked by methionine sulphoximine.
Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Cerebellum; Cerebral Cortex; Glucose; Glutamates; Glycogen; Lactates; Male; Methionine Sulfoximine; Methods; Phosphocreatine; Rats; Seizures; Time Factors | 1969 |
Behavioral and convulsive phenomena induced in the cat by methionine sulfoximine. Ablation and electrographic studies.
Topics: Animals; Behavior, Animal; Brain Diseases; Cats; Electroencephalography; Methionine; Methionine Sulfoximine; Seizures | 1965 |
Cerebral lysosomes. 3. Evidence for in vivo "labilization" by the convulsant DL-methionine-DL-sulfoximine.
Topics: Acid Phosphatase; Animals; Brain; Glycoside Hydrolases; In Vitro Techniques; Lysosomes; Methionine; Methionine Sulfoximine; Rats; Seizures | 1966 |
Effect of atropine and eserine on the episodic behavioral and electrographic manifestations induced by methionine sulfoximine.
Topics: Animals; Atropine; Behavior, Animal; Cats; Electroencephalography; Fear; Methionine; Methionine Sulfoximine; Physostigmine; Rats; Seizures; Sound | 1966 |