beta-carboline-3-carboxylic acid methyl ester has been researched along with Seizures in 28 studies
*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (39.29) | 18.7374 |
| 1990's | 12 (42.86) | 18.2507 |
| 2000's | 5 (17.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eigyo, M; Kawasaki, K; Matsushita, A; Murata, S; Sasatani, T; Shindo, H; Takada, S | 1 |
| Da Settimo, A; Da Settimo, F; Gesi, M; Giannaccini, G; Greco, G; Lucacchini, A; Marini, AM; Martini, C; Novellino, E; Primofiore, G | 1 |
| Chapouthier, G; Dodd, RH; Grecksch, G; Krug, M; Rössler, AS; Rüthrich, H | 1 |
| Chaix, Y; Ferraro, TN; Lapouble, E; Martin, B | 1 |
| Cavalheiro, E; Chapouthier, G; Dodd, RH; Kaijima, M; Potier, P; Prado de Carvalho, L; Rossier, J; Valin, A; Venault, P | 1 |
| Paul, SM; Schweri, MM; Skolnick, P | 1 |
| Cain, M; Cook, J; Paul, S; Schweri, M; Skolnick, P | 1 |
| Martin, JV; Mendelson, WB; Paul, SM; Schweri, MM; Skolnick, P; Wagner, RL | 1 |
| Morel, E; Perrault, G; Sanger, DJ; Zivkovic, B | 1 |
| Crawley, JN; Mathis, C; Paul, SM | 1 |
| Chiu, TH; Rosenberg, HC; Zhao, TJ | 1 |
| Bondoux, D; Chapouthier, G; Clément, Y; Launay, JM; Martin, B; Robel, P; Venault, P; Young, J | 1 |
| Chapouthier, G; Clément, Y; Martin, B; Venault, P | 1 |
| Chimirri, A; De Sarro, A; De Sarro, G; Guisti, P; Lipartiti, M; Zappala, M | 1 |
| Bondoux, D; Chapouthier, G; Clément, Y; Launay, JM | 1 |
| Chimirri, A; De Sarro, A; De Sarro, G; Giusti, P; McKernan, R; Quirk, K | 1 |
| Gershenfeld, HK; Li, X; Neumann, PE; Paul, SM; St Jean, PL | 1 |
| Chapouthier, G; Dodd, RH; Launay, JM; Rössler, AS; Venault, P | 1 |
| Bondoux, D; Chapouthier, G; Clément, Y; Launay, JM; Martin, B; Venault, P | 1 |
| Adrien, J; Boutre, B; Boutrel, B; Chapouthier, G; Rinaldi, D; Venault, P | 1 |
| Bondoux, D; Chapouthier, G; Desforges, C; Launay, JM; Martin, B | 1 |
| Bottlaender, M; Brouillet, E; Chavoix, C; Dodd, RH; Fournier, D; Hantraye, P; Khalili-Varasteh, M; Mazière, M | 1 |
| Chapman, AG; Cheetham, SC; Hart, GP; Meldrum, BS; Westerberg, E | 1 |
| Belzung, C; Misslin, R; Vogel, E | 1 |
| Little, H; Nutt, DJ | 1 |
| Costello, MJ; Nutt, DJ | 1 |
| Conti-Tronconi, B; Costa, E; Ferrero, P; Guidotti, A; Santi, MR | 1 |
| Bortolotto, ZA; Cavalheiro, EA; Ikonomidou, C; Mello, LE; Turski, L; Turski, WA | 1 |
1 review(s) available for beta-carboline-3-carboxylic acid methyl ester and Seizures
| Article | Year |
|---|---|
Chemoconvulsant-induced seizure susceptibility: toward a common genetic basis?
Topics: Animals; Carbolines; Chromosome Mapping; Chromosomes; Convulsants; GABA Agonists; Genetic Predisposition to Disease; Humans; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Pentylenetetrazole; Potassium Channels; Quantitative Trait Loci; Seizures | 2007 |
27 other study(ies) available for beta-carboline-3-carboxylic acid methyl ester and Seizures
| Article | Year |
|---|---|
A new thienylpyrazoloquinoline: a potent and orally active inverse agonist to benzodiazepine receptors.
Topics: Administration, Oral; Animals; Anticonvulsants; Indicators and Reagents; Male; Mice; Pentylenetetrazole; Pyrazoles; Quinolines; Receptors, GABA-A; Seizures; Thiophenes | 1987 |
N'-Phenylindol-3-ylglyoxylohydrazide derivatives: synthesis, structure-activity relationships, molecular modeling studies, and pharmacological action on brain benzodiazepine receptors.
Topics: Animals; Anticonvulsants; Binding, Competitive; Brain; Cattle; Cerebral Cortex; Convulsants; Diazepam; Flumazenil; GABA Modulators; Glyoxylates; Hydrazines; In Vitro Techniques; Indoles; Ligands; Mice; Models, Molecular; Molecular Conformation; Receptors, GABA-A; Seizures; Structure-Activity Relationship | 1998 |
Long-lasting potentiation effects induced in rats by kindling with an inverse agonist of the benzodiazepine receptor.
Topics: Animals; Behavior, Animal; Carbolines; Convulsants; Dentate Gyrus; Electric Stimulation; Electrodes, Implanted; Evoked Potentials; GABA Agonists; GABA-A Receptor Agonists; Kindling, Neurologic; Long-Term Potentiation; Male; Pentylenetetrazole; Perforant Pathway; Rats; Rats, Wistar; Seizures; Synapses | 2002 |
Distinct behavioral and pharmacological effects of two benzodiazepine antagonists: Ro 15-1788 and methyl beta-carboline.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepinones; Carbolines; Cats; Drug Synergism; Electroencephalography; Electrophysiology; Flumazenil; Indoles; Mice; Papio; Pentylenetetrazole; Seizures; Species Specificity | 1983 |
Strain differences in susceptibility to the convulsant actions of 3-carbomethoxy-beta-carboline.
Topics: Animals; Brain; Carbolines; Convulsants; Diazepam; Disease Susceptibility; Indoles; Male; Mice; Mice, Inbred Strains; Seizures; Species Specificity | 1983 |
Blockade of 3-carbomethoxy-beta-carboline induced seizures by diazepam and the benzodiazepine antagonists, Ro 15-1788 and CGS 8216.
Topics: Animals; Benzodiazepinones; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Harmaline; Indoles; Male; Mice; Pyrazoles; Seizures; Tremor | 1982 |
3-carboethoxy-beta-carboline (beta-CCE) elicits electroencephalographic seizures in rats: reversal by the benzodiazepine antagonist CGS 8216.
Topics: Animals; Benzodiazepines; Brain; Carbolines; Electroencephalography; Indoles; Male; Pyrazoles; Rats; Rats, Inbred Strains; Seizures | 1983 |
Repeated treatment with alpidem, a new anxiolytic, does not induce tolerance or physical dependence.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Drug Tolerance; Flumazenil; Imidazoles; Isoniazid; Male; Mice; Pentylenetetrazole; Pyridines; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1993 |
Characterization of benzodiazepine-sensitive behaviors in the A/J and C57BL/6J inbred strains of mice.
Topics: Animals; Arousal; Avoidance Learning; Carbolines; Convulsants; Diazepam; Exploratory Behavior; Female; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Models, Genetic; Receptors, GABA-A; Seizures | 1994 |
Treatment with an antisense oligodeoxynucleotide to the GABAA receptor gamma 2 subunit increases convulsive threshold for beta-CCM, a benzodiazepine "inverse agonist', in rats.
Topics: Analysis of Variance; Animals; Body Weight; Carbolines; Convulsants; Injections, Intraventricular; Male; Oligonucleotides, Antisense; Picrotoxin; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Seizures; Strychnine | 1996 |
A mouse mutant strain highly resistant to methyl beta-carboline-3-carboxylate-induced seizures.
Topics: Animals; Brain Chemistry; Carbolines; Convulsants; Drug Resistance; Evaluation Studies as Topic; Female; Male; Mice; Mice, Mutant Strains; Pentylenetetrazole; Pregnanolone; Pregnenolone; Radioligand Assay; Receptors, GABA-A; Seizures | 1996 |
Mouse chromosome 9 involvement in beta-CCM-induced seizures.
Topics: Animals; Carbolines; Chromosome Mapping; Convulsants; Crosses, Genetic; Disease Susceptibility; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Seizures | 1996 |
Azirino[1, 2-d][1, 4]benzodiazepine derivatives and related 1,4-benzodiazepines as anticonvulsant agents in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzodiazepines; Binding, Competitive; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; Convulsants; Flumazenil; GABA Modulators; Male; Mice; Mice, Inbred DBA; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1996 |
Convulsive effects of a benzodiazepine receptor inverse agonist: are they related to anxiogenic processes?
Topics: Animals; Anxiety; Behavior, Animal; Carbolines; Convulsants; Female; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Receptors, GABA-A; Seizures | 1997 |
Anticonvulsant activity of azirino[1,2-d][1,4]benzodiazepines and related 1,4-benzodiazepines in mice.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbolines; Cell Line; Convulsants; Flumazenil; GABA Modulators; Male; Membranes; Mice; Mice, Inbred DBA; Movement; Pentylenetetrazole; Radioligand Assay; Receptors, GABA-A; Seizures | 1997 |
Mapping quantitative trait loci for seizure response to a GABAA receptor inverse agonist in mice.
Topics: Animals; Behavior, Animal; Carbolines; Chromosome Mapping; Chromosome Segregation; Convulsants; Female; GABA Agonists; Genetic Linkage; Genetic Predisposition to Disease; Humans; Lod Score; Male; Mice; Mice, Inbred Strains; Phenotype; Quantitative Trait, Heritable; Seizures | 1999 |
Changes in benzodiazepine binding in a subkindling situation.
Topics: Animals; Carbolines; Convulsants; Disease Models, Animal; Epilepsy; Flumazenil; GABA Antagonists; Kindling, Neurologic; Male; Mice; Receptors, GABA-A; Seizures; Tritium | 2000 |
Chromosomes 4 and 13 in beta-carboline-induced seizures in mice: benzodiazepine binding.
Topics: Animals; Brain; Carbolines; Chromosome Mapping; Convulsants; Flumazenil; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Radioligand Assay; Receptors, GABA-A; Seizures; Species Specificity; Tritium | 2000 |
Two mouse lines selected for differential sensitivities to beta-carboline-induced seizures are also differentially sensitive to various pharmacological effects of other GABA(A) receptor ligands.
Topics: Animals; Brain; Carbolines; Convulsants; Female; GABA Agonists; Male; Mice; Mice, Inbred Strains; Receptors, GABA-A; Seizures; Selection, Genetic | 2000 |
Genetic difference in sensitivity to beta-carboline: evidence for the involvement of brain benzodiazepine receptors.
Topics: Animals; Brain; Carbolines; Clonazepam; Convulsants; Flunitrazepam; Kinetics; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, GABA-A; Seizures; Species Specificity; Strychnine | 1991 |
In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cerebral Cortex; Diazepam; Electroencephalography; Flumazenil; gamma-Aminobutyric Acid; Ligands; Male; Papio; Pentylenetetrazole; Receptors, GABA-A; Seizures; Synaptic Transmission; Tomography, Emission-Computed | 1991 |
Effects of two convulsant beta-carboline derivatives, DMCM and beta-CCM, on regional neurotransmitter amino acid levels and on in vitro D-[3H]aspartate release in rodents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Carbolines; Cerebellum; Cerebral Cortex; Convulsants; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamine; Hippocampus; Indoles; Male; Mice; Mice, Inbred DBA; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Seizures | 1985 |
The benzodiazepine receptor inverse agonists beta-CCM and RO 15-3505 both reverse the anxiolytic effects of ethanol in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Carbolines; Ethanol; Male; Mice; Pentylenetetrazole; Seizures | 1988 |
Benzodiazepine-receptor mediated convulsions in infant rats: effects of beta-carbolines.
Topics: Animals; Bicuculline; Carbolines; Convulsants; Flurazepam; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1986 |
Rapid induction of lorazepam dependence and reversal with flumazenil.
Topics: Animals; Carbolines; Flumazenil; Lorazepam; Male; Mice; Mice, Inbred Strains; Seizures; Substance-Related Disorders | 1988 |
Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; Benzodiazepinones; Brain Chemistry; Carbolines; Chromatography, High Pressure Liquid; Diazepam Binding Inhibitor; Enzyme-Linked Immunosorbent Assay; Flumazenil; Flunitrazepam; Male; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Rats; Rats, Inbred Strains; Seizures; Synaptic Membranes | 1986 |
Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Animals; Benzodiazepinones; Bicuculline; Brain; Carbolines; Convulsants; Electroencephalography; Flumazenil; Male; Motor Activity; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1985 |