| Assay ID | Title | Year | Journal | Article |
|---|
| AID1476510 | Inhibition of mouse GAT2 expressed in hamster BHK cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method | 2017 | Journal of medicinal chemistry, 11-09, Volume: 60, Issue:21
| Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1). |
| AID631157 | Inhibition of mouse GAT4-mediated [3H]GABA uptake expressed in BHK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID1195451 | Inhibition of mouse mGAT4 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintillation counting analysis | 2015 | Bioorganic & medicinal chemistry, May-15, Volume: 23, Issue:10
| Structure activity relationship of selective GABA uptake inhibitors. |
| AID764975 | Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
| Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: identification of an efficient lead for potent inhibitors of GABA transports. |
| AID1188930 | Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | 2014 | ACS medicinal chemistry letters, Aug-14, Volume: 5, Issue:8
| Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor. |
| AID1195448 | Inhibition of mouse mGAT1 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintillation counting analysis | 2015 | Bioorganic & medicinal chemistry, May-15, Volume: 23, Issue:10
| Structure activity relationship of selective GABA uptake inhibitors. |
| AID631155 | Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in BHK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID1188931 | Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | 2014 | ACS medicinal chemistry letters, Aug-14, Volume: 5, Issue:8
| Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor. |
| AID1195449 | Inhibition of mouse mGAT2 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintillation counting analysis | 2015 | Bioorganic & medicinal chemistry, May-15, Volume: 23, Issue:10
| Structure activity relationship of selective GABA uptake inhibitors. |
| AID631147 | Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in human HEK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID1476509 | Inhibition of mouse GAT1 expressed in hamster BHK cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method | 2017 | Journal of medicinal chemistry, 11-09, Volume: 60, Issue:21
| Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1). |
| AID631146 | Inhibition of mouse GAT1-mediated [3H]GABA uptake expressed in human HEK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID1188933 | Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | 2014 | ACS medicinal chemistry letters, Aug-14, Volume: 5, Issue:8
| Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor. |
| AID631154 | Inhibition of mouse GAT1-mediated [3H]GABA uptake expressed in BHK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID631149 | Inhibition of mouse GAT4-mediated [3H]GABA uptake expressed in human HEK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID1195450 | Inhibition of mouse mGAT3 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintillation counting analysis | 2015 | Bioorganic & medicinal chemistry, May-15, Volume: 23, Issue:10
| Structure activity relationship of selective GABA uptake inhibitors. |
| AID1188934 | Selectivity index, ratio of IC50 for human GAT3 to IC50 for human BGT1 | 2014 | ACS medicinal chemistry letters, Aug-14, Volume: 5, Issue:8
| Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor. |
| AID1476512 | Inhibition of mouse BGT1 expressed in hamster BHK cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method | 2017 | Journal of medicinal chemistry, 11-09, Volume: 60, Issue:21
| Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1). |
| AID631156 | Inhibition of mouse GAT3-mediated [3H]GABA uptake expressed in BHK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID631148 | Inhibition of mouse GAT3-mediated [3H]GABA uptake expressed in human HEK cells | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation. |
| AID1188932 | Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | 2014 | ACS medicinal chemistry letters, Aug-14, Volume: 5, Issue:8
| Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor. |
| AID1476511 | Inhibition of mouse GAT3 expressed in hamster BHK cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method | 2017 | Journal of medicinal chemistry, 11-09, Volume: 60, Issue:21
| Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1). |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1346975 | Mouse BGT1 (GABA transporter subfamily) | 1997 | British journal of pharmacology, Mar, Volume: 120, Issue:6
| 1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |