aztreonam has been researched along with Seizures in 3 studies
Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although the main mechanism for seizure-like activity of monobactams cannot be easily determined, we believe that several mechanisms may be involved." | 1.29 | Comparative epileptogenic properties of two monobactam derivatives in C57, Swiss and DBA/2 mice. ( De Sarro, A; De Sarro, GB; Imperatore, C; Naccari, F, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Billnitzer, A | 1 |
| Kaplan, PW | 1 |
| Reck, F | 1 |
| Bermingham, A | 1 |
| Blais, J | 1 |
| Capka, V | 1 |
| Cariaga, T | 1 |
| Casarez, A | 1 |
| Colvin, R | 1 |
| Dean, CR | 1 |
| Fekete, A | 1 |
| Gong, W | 1 |
| Growcott, E | 1 |
| Guo, H | 1 |
| Jones, AK | 1 |
| Li, C | 1 |
| Li, F | 1 |
| Lin, X | 1 |
| Lindvall, M | 1 |
| Lopez, S | 1 |
| McKenney, D | 1 |
| Metzger, L | 1 |
| Moser, HE | 1 |
| Prathapam, R | 1 |
| Rasper, D | 1 |
| Rudewicz, P | 1 |
| Sethuraman, V | 1 |
| Shen, X | 1 |
| Shaul, J | 1 |
| Simmons, RL | 1 |
| Tashiro, K | 1 |
| Tang, D | 1 |
| Tjandra, M | 1 |
| Turner, N | 1 |
| Uehara, T | 1 |
| Vitt, C | 1 |
| Whitebread, S | 1 |
| Yifru, A | 1 |
| Zang, X | 1 |
| Zhu, Q | 1 |
| De Sarro, A | 1 |
| Naccari, F | 1 |
| Imperatore, C | 1 |
| De Sarro, GB | 1 |
3 other studies available for aztreonam and Seizures
| Article | Year |
|---|---|
Generalized Periodic Discharges With Triphasic Morphology in the Setting of Aztreonam Neurotoxicity.
Topics: Aged; Aztreonam; Brain; Brain Waves; Electroencephalography; Female; Humans; Patient Discharge; Seiz | 2021 |
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamas | 2018 |
Comparative epileptogenic properties of two monobactam derivatives in C57, Swiss and DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Aztreonam; Cerebral Cortex; Convulsants; Electroencephalography; Inje | 1996 |