beta-hydroxy-beta-ethyl-phenylpropionamide: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 64814 |
| CHEMBL ID | 4303634 |
| SCHEMBL ID | 5898588 |
| MeSH ID | M0185487 |
| Synonym |
|---|
| 5579-03-3 |
| beta-ethyl-beta-hydroxybenzenepropanamide |
| dl-hepp |
| beta-hydroxy-beta-ethyl-phenylpropionamide |
| benzenepropanamide, beta-ethyl-beta-hydroxy- |
| 3-hydroxy-3-ethyl-3-phenylpropionamide |
| hydrocinnamamide, beta-ethyl-beta-hydroxy- |
| 3-hydroxy-3-phenylpentanamide |
| AKOS006276539 |
| 131802-69-2 |
| 3-hppt |
| benzenepropanamide, beta-ethyl-beta-hydroxy-, (+-)- |
| 3-hydroxy-3-phenylpentamide |
| SCHEMBL5898588 |
| DTXSID50927354 |
| CHEMBL4303634 |
| EN300-254496 |
| Z1198158614 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " The sensitivity, accuracy and reproducibility of the method were shown to be satisfactory for pharmacokinetic studies of HEPP." | ( Plasma determination of the novel anticonvulsant D,L-3-hydroxy-3-ethyl-3-phenylpropionamide and preliminary pharmacokinetic studies in the rat. Gomez, LE; Lehmann, PA, 1992) | 0.28 |
| " The mean terminal half-life (t1/2 beta) was the same after the three doses (3." | ( Pharmacokinetics of the novel anticonvulsant HEPP after single intravenous administration of three different doses in dogs. Gómez, LE; Lehmann, PA, 1995) | 0.29 |
| "03 microg h mL(-1)), the elimination half-life was also significantly (P<0." | ( Pharmacokinetic interaction in rabbits between a new anticonvulsant, DL-3-hydroxy-3-ethyl-3-phenylpropionamide, and phenytoin. Fernández, A; García, L; Jung, H; Medina, L; Pérez, R, 1998) | 0.3 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " Embryotoxicity was mainly indicated by a significant dose-concentration dependency in the increase in resorptions, high percentage of fully resorbed litters, and decrease in embryo body weights during the GD6-14 dosing period." | ( Gestational age dependency in the prenatal toxicity and in the disposition kinetics of the novel anticonvulsant HEPP (D,L-3-hydroxy-3-ethyl-3-phenylpropionamide) after subcutaneous administration in pregnant rats. Gómez-Martínez, LE, ) | 0.13 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (81.82) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.64) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (7.69%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (92.31%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||