4-hydroxycordoin and Seizures

4-hydroxycordoin has been researched along with Seizures* in 1 studies

Other Studies

1 other study(ies) available for 4-hydroxycordoin and Seizures

ArticleYear
Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents.
    Bioorganic & medicinal chemistry letters, 2009, Sep-15, Volume: 19, Issue:18

    In this study, we synthesized some natural and semi-synthetic prenyloxyphenylpropanoids (e.g., acetophenones, benzoic and cinnamic acids, chalcones, and coumarins), and we assessed their in vivo neuroprotective activity, using the mouse maximal electroshock-induced seizure model (MES test). 7-Isopentenyloxycoumarin and (2E)-3-{4-[(3-methylbut-2-enyl)oxy]phenyl}prop-2-enoic acid, administered ip at a dose of 300 mg/kg, suppressed MES-induced seizures in mice in a time- and dose-dependent manner.

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hemiterpenes; Mice; Phenyl Ethers; Seizures

2009