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anthranilic acid and Seizures

anthranilic acid has been researched along with Seizures in 3 studies

anthranilic acid: RN given refers to parent cpd; structure in Negwer, 5th ed, #565
anthranilic acid : An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Seizure frequency was recorded using seizure diaries."6.79The effects of vagus nerve stimulation on tryptophan metabolites in children with intractable epilepsy. ( Aalbers, MW; Aldenkamp, AP; Kessels, AG; Klinkenberg, S; Leenen, L; Majoie, HJ; Rijkers, K; van den Borne, CJ; Verschuure, P; Vles, JS, 2014)
") or gavage administration of the KYN pathway blocking drug Ro 61-8048, both of which enter the brain from the circulatory system, affect the time to first convulsion and/or coma during HBO in a manner consistent with a modulatory role for seizure activity."3.70Evidence that kynurenine pathway metabolites mediate hyperbaric oxygen-induced convulsions. ( Amiridze, N; Brown, OR; Dale, WE; Dang, Y, 2000)
"Seizure frequency was recorded using seizure diaries."2.79The effects of vagus nerve stimulation on tryptophan metabolites in children with intractable epilepsy. ( Aalbers, MW; Aldenkamp, AP; Kessels, AG; Klinkenberg, S; Leenen, L; Majoie, HJ; Rijkers, K; van den Borne, CJ; Verschuure, P; Vles, JS, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klinkenberg, S1
van den Borne, CJ1
Aalbers, MW1
Verschuure, P1
Kessels, AG1
Leenen, L1
Rijkers, K1
Aldenkamp, AP1
Vles, JS1
Majoie, HJ1
Guzeva, VI1
Mikhailov, IB1
Melnikova, NV1
Dale, WE1
Dang, Y1
Amiridze, N1
Brown, OR1

Trials

1 trial available for anthranilic acid and Seizures

ArticleYear
The effects of vagus nerve stimulation on tryptophan metabolites in children with intractable epilepsy.
    Epilepsy & behavior : E&B, 2014, Volume: 37

    Topics: Adolescent; Affect; Biotransformation; Child; Child, Preschool; Double-Blind Method; Drug Resistance

2014

Other Studies

2 other studies available for anthranilic acid and Seizures

ArticleYear
The kynurenines and the seizures.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Animals; Cerebral Ventricles; Electroencephalography; Hippocampus; Kynurenic Acid; Kynurenine; Micro

1996
Evidence that kynurenine pathway metabolites mediate hyperbaric oxygen-induced convulsions.
    Toxicology letters, 2000, Sep-30, Volume: 117, Issue:1-2

    Topics: Animals; Coma; Enzyme Inhibitors; Hyperbaric Oxygenation; Kynurenine; Kynurenine 3-Monooxygenase; Ma

2000