beta-carboline-3-carboxylic acid ethyl ester has been researched along with Seizures in 21 studies
*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (90.48) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eigyo, M; Matsushita, A; Murata, S; Shindo, H; Takada, S | 1 |
| Eigyo, M; Kawasaki, K; Matsushita, A; Murata, S; Sasatani, T; Shindo, H; Takada, S | 1 |
| Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P | 1 |
| Baldino, F; Geller, HM; Krespan, B | 1 |
| Paul, SM; Skolnick, P | 1 |
| Nutt, D | 1 |
| Braestrup, C; Honoré, T; Jensen, LH; Petersen, EN | 1 |
| Hirsch, JD; Tenen, SS | 1 |
| Cowen, PJ; Green, AR; Nutt, DJ | 1 |
| Besselièvre, R; Cepeda, C; Naquet, R; Potier, P; Rossier, J; Tanaka, T | 1 |
| Cowen, PJ; Little, HJ; Nutt, DJ | 1 |
| Airaksinen, MM; Saano, V | 1 |
| Braestrup, C; Honoré, T; Jensen, LH; Nielsen, M; Petersen, EN | 1 |
| Biggio, G; Concas, A; Crisponi, G; Nurchi, V; Salis, M; Serra, M | 1 |
| Martin, JV; Mendelson, WB; Paul, SM; Schweri, MM; Skolnick, P; Wagner, RL | 1 |
| Jones, BJ; Oakley, NR | 1 |
| Andre, E; Anton, G; Aubin, HJ; Lagarde, D; Laurent, J; Milhaud, C | 1 |
| Fletcher, A; Forster, EA | 1 |
| Caporali, MG; Gatta, F; Lucantoni, D; Massotti, M; Mele, L | 1 |
| Vellucci, SV; Webster, RA | 1 |
| Biry, P; Pieri, L | 1 |
3 review(s) available for beta-carboline-3-carboxylic acid ethyl ester and Seizures
| Article | Year |
|---|---|
The mechanism(s) of action of the benzodiazepines.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Carbolines; Cats; Cattle; Diazepam; gamma-Aminobutyric Acid; Humans; Molecular Weight; Muscle Relaxation; Neurotransmitter Agents; Niacinamide; Purines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures; Sleep Wake Disorders | 1981 |
Differential pharmacological effects of benzodiazepine receptor inverse agonists.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Carbolines; Convulsants; Electroshock; Humans; Mice; Pentylenetetrazole; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
Benzodiazepine receptor ligands with positive and negative efficacy.
Topics: Acoustic Stimulation; Animals; Carbolines; Chlorides; gamma-Aminobutyric Acid; Humans; Ligands; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
18 other study(ies) available for beta-carboline-3-carboxylic acid ethyl ester and Seizures
| Article | Year |
|---|---|
Thienylpyrazoloquinolines with high affinity to benzodiazepine receptors: continuous shift from inverse agonist to agonist properties depending on the size of the alkyl substituent.
Topics: Animals; Chemical Phenomena; Chemistry; Diazepam; Drug Synergism; Male; Mice; Molecular Structure; Pentylenetetrazole; Pyrazoles; Quinolines; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thiophenes | 1989 |
A new thienylpyrazoloquinoline: a potent and orally active inverse agonist to benzodiazepine receptors.
Topics: Administration, Oral; Animals; Anticonvulsants; Indicators and Reagents; Male; Mice; Pentylenetetrazole; Pyrazoles; Quinolines; Receptors, GABA-A; Seizures; Thiophenes | 1987 |
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship | 1998 |
Anticonvulsant actions of fominoben: possible involvement of benzodiazepine receptors.
Topics: 3-Mercaptopropionic Acid; Aminophylline; Animals; Anticonvulsants; Benzodiazepinones; Binding, Competitive; Brain Chemistry; Carbolines; Flumazenil; Male; Mice; Morpholines; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Synaptosomes | 1984 |
Pharmacological and behavioural studies of benzodiazepine antagonists and contragonists.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepinones; Carbolines; Conditioning, Operant; Conflict, Psychological; Flumazenil; Ganglia, Spinal; Hippocampus; Male; Rats; Seizures; Social Behavior | 1983 |
beta-Carboline-3-carboxylic acid ethyl ester antagonizes diazepam activity.
Topics: Animals; Binding, Competitive; Brain; Carbolines; Diazepam; Drug Synergism; Indoles; Membranes; Pentylenetetrazole; Rats; Receptors, Drug; Receptors, GABA-A; Seizures | 1980 |
Ethyl beta-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats.
Topics: Animals; Bicuculline; Carbolines; Dose-Response Relationship, Drug; Flurazepam; Indoles; Rats; Receptors, Drug; Receptors, GABA-A; Seizures | 1981 |
Proconvulsant effects in baboons of beta-carboline, a putative endogenous ligand for benzodiazepine receptors.
Topics: Amygdala; Animals; Benzodiazepines; Carbolines; Indoles; Kainic Acid; Ligands; Light; Papio; Receptors, Drug; Receptors, GABA-A; Seizures | 1981 |
Unusual interactions of benzodiazepine receptor antagonists.
Topics: Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Biological Assay; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Indoles; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures | 1982 |
Binding of beta-carbolines and caffeine on benzodiazepine receptors: correlations to convulsions and tremor.
Topics: Animals; Brain; Caffeine; Carbolines; Flunitrazepam; Harmaline; Harmine; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Tremor | 1982 |
Evidence for an involvement of GABA receptors in the mediation of the proconvulsant action of ethyl-beta-carboline-3-carboxylate.
Topics: Animals; Binding Sites; Carbolines; Cerebral Cortex; Drug Synergism; gamma-Aminobutyric Acid; Hippocampus; Indoles; Injections, Intraventricular; Isoniazid; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1984 |
3-carboethoxy-beta-carboline (beta-CCE) elicits electroencephalographic seizures in rats: reversal by the benzodiazepine antagonist CGS 8216.
Topics: Animals; Benzodiazepines; Brain; Carbolines; Electroencephalography; Indoles; Male; Pyrazoles; Rats; Rats, Inbred Strains; Seizures | 1983 |
Differential pharmacological effects of beta-carboline-3-carboxylic acid esters.
Topics: Animals; Carbolines; Cerebellum; Cerebral Cortex; Electroshock; Indoles; Male; Muridae; Seizures | 1982 |
Behavioral effects induced by beta CCE in free or restrained rhesus monkeys (Macaca mulatta).
Topics: Animals; Anxiety; Behavior, Animal; Carbolines; Convulsants; Dose-Response Relationship, Drug; Injections, Intravenous; Macaca mulatta; Seizures | 1990 |
A proconvulsant action of selective alpha 2-adrenoceptor antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bicuculline; Carbolines; Convulsants; Male; Mice; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Strychnine | 1988 |
Supraspinal convulsions induced by inverse benzodiazepine agonists in rabbits.
Topics: Animals; Benzodiazepinones; Carbolines; Diazepam; Electroencephalography; Flumazenil; Male; Pyrazoles; Rabbits; Receptors, GABA-A; Seizures | 1985 |
The effects of beta-carboline carboxylic acid ethyl ester and its free acid, administered ICV, on the anticonvulsant activity of diazepam and sodium valproate in the mouse.
Topics: Animals; Benzodiazepinones; Carbolines; Diazepam; Drug Interactions; Female; Mice; Mice, Inbred C3H; Pentylenetetrazole; Receptors, GABA-A; Seizures; Valproic Acid | 1986 |
Isoniazid-induced convulsions in rats: effects of Ro 15-1788 and beta-CCE.
Topics: Animals; Benzodiazepinones; Carbolines; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Indoles; Isoniazid; Male; Rats; Rats, Inbred Strains; Seizures | 1985 |