Page last updated: 2024-08-24

lubeluzole and Seizures

lubeluzole has been researched along with Seizures in 2 studies

*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amitay, O; Baxter, D; Berlove, D; Connaughton, S; Durant, GJ; Fischer, JB; Guo, JQ; Hu, LY; Maillard, MC; McBurney, RN; Nagy, PI; Perlman, ME; Subbarao, K; Yost, EA; Zhang, L1
Bechtel, WD; Carter, AJ; Grauert, M; Nar, H; Stransky, W; Weiser, T1

Other Studies

2 other study(ies) available for lubeluzole and Seizures

ArticleYear
Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.
    Journal of medicinal chemistry, 1998, Jul-30, Volume: 41, Issue:16

    Topics: Animals; Anticonvulsants; Biological Transport; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; CHO Cells; Cricetinae; Drug Design; Female; Guanidine; Imidazoles; Male; Mice; Mice, Inbred DBA; Molecular Conformation; Neurons; Pyrimidines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Synaptosomes

1998
Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Benzomorphans; Cerebral Cortex; Corpus Striatum; Crystallography, X-Ray; Electroshock; Glutamic Acid; In Vitro Techniques; Male; Mice; Neuroprotective Agents; Radioligand Assay; Rats; Seizures; Sodium Channel Blockers; Stroke; Structure-Activity Relationship; Thromboembolism; Veratridine

2002