pyrrolidine-2,4-dicarboxylic acid has been researched along with Seizures in 1 studies
pyrrolidine-2,4-dicarboxylic acid: a glutamate uptake inhibitor
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings indicate that seizures are not necessarily accompanied by an increased extracellular glutamate level and that increased glutamatergic excitation in epilepsy may result from other abnormalities such as increased density of glutamate receptors, enhanced activation subsequent to reduced modulation, or sprouting of glutamatergic synapses." | 1.29 | Evidence disputing the link between seizure activity and high extracellular glutamate. ( Obrenovitch, TP; Urenjak, J; Zilkha, E, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Obrenovitch, TP | 1 |
| Urenjak, J | 1 |
| Zilkha, E | 1 |
1 other study available for pyrrolidine-2,4-dicarboxylic acid and Seizures
| Article | Year |
|---|---|
Evidence disputing the link between seizure activity and high extracellular glutamate.
Topics: Animals; Dicarboxylic Acids; Electroencephalography; Electrophysiology; Excitatory Amino Acid Antago | 1996 |