| Assay ID | Title | Year | Journal | Article |
|---|
| AID433892 | Toxicity in Kunming mouse assessed as subcutaneous pentylenetetrazole-induced lethality at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433887 | Anticonvulsant activity in ip dosed Kunming mouse assessed as protection against maximal electroshock-induced seizures | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433896 | Toxicity in Kunming mouse assessed as isoniazid-induced lethality at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID117815 | Ability to produce neurological deficit in the rotarod test (10 mice were used per dose, ip) | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| Sleep-inducing N-alkyl-5-[m-(trifluoromethyl)phenyl]-5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)cinnamamides. |
| AID433898 | Toxicity in Kunming mouse assessed as 3-mercaptopropionic acid-induced lethality at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID114174 | Effective dose against Mice ataxia, ip administration | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| Sleep-inducing N-alkyl-5-[m-(trifluoromethyl)phenyl]-5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)cinnamamides. |
| AID433897 | Anticonvulsant activity against 3-mercaptopropionic acid-induced seizures in Kunming mouse assessed as tonic seizures of at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433893 | Anticonvulsant activity against isoniazid-induced seizures in Kunming mouse assessed as clonic seizures of at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID184647 | Lethal dose was obtained by 2-h post administration (ip), using four male Royal Hart Wistar rats | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| Sleep-inducing N-alkyl-5-[m-(trifluoromethyl)phenyl]-5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)cinnamamides. |
| AID113445 | Anticonvulsant activity against N-sulfamoylhexahydrozepine (10 mice were used per dose, ip) | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| Sleep-inducing N-alkyl-5-[m-(trifluoromethyl)phenyl]-5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)cinnamamides. |
| AID119063 | Ability to reinduce anesthesia (70 mg/kg, iv) following recovery of loss of righting reflex obtained with hexobarbital. | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| Sleep-inducing N-alkyl-5-[m-(trifluoromethyl)phenyl]-5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)cinnamamides. |
| AID433901 | Toxicity in Kunming mouse assessed as thiosemicarbazide-induced lethality at 50 mg/kg, ip after 2.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433885 | Anticonvulsant activity in Kunming mouse assessed as protection against maximal electroshock-induced seizures at 30 mg/kg, ip after 4 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433888 | Neurotoxicity in ip dosed Kunming mouse by rotarod test | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID114181 | Effective dose against loss of righting reflex in mice (10 mice per dose, ip) | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| Sleep-inducing N-alkyl-5-[m-(trifluoromethyl)phenyl]-5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)cinnamamides. |
| AID433900 | Anticonvulsant activity against thiosemicarbazide-induced seizures in Kunming mouse assessed as tonic seizures of at 50 mg/kg, ip after 2.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID114701 | Effective dose against Mice docility, ip administration | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| Sleep-inducing N-alkyl-5-[m-(trifluoromethyl)phenyl]-5-hydroxy-2-pyrrolidinones and N-alkyl-3-(trifluoromethyl)cinnamamides. |
| AID433895 | Anticonvulsant activity against isoniazid-induced seizures in Kunming mouse assessed as tonic seizures of at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433894 | Anticonvulsant activity against 3-mercaptopropionic acid-induced seizures in Kunming mouse assessed as clonic seizures of at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433891 | Anticonvulsant activity against subcutaneous pentylenetetrazole-induced seizures in Kunming mouse assessed as tonic seizures of at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433899 | Anticonvulsant activity against thiosemicarbazide-induced seizures in Kunming mouse assessed as clonic seizures of at 50 mg/kg, ip after 2.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433889 | Protective index, ratio of TD50 for neurotoxicity to ED50 for anticonvulsant activity in ip dosed Kunming mouse | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID433890 | Anticonvulsant activity against subcutaneous pentylenetetrazole-induced seizures in Kunming mouse assessed as clonic seizures of at 50 mg/kg, ip after 0.5 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9
| Synthesis and anticonvulsant activity of N-(2-hydroxyethyl) cinnamamide derivatives. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347407 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347425 | Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347424 | RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID504749 | qHTS profiling for inhibitors of Plasmodium falciparum proliferation | 2011 | Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
| Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |