promethazine has been researched along with Seizures in 22 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 1988), 79 patients of eclampsia were treated with lytic cocktail and in time period B (April 1992-April 1994), 104 eclamptic patients were treated with magnesium sulfate." | 3.70 | Comparison of lytic cocktail and magnesium sulphate regimens in eclampsia: a retrospective analysis. ( Rani, K; Sawhney, H; Vasishta, K, 1998) |
| "Pethidine/promethazine and fentanyl/droperidol reduced the susceptibility to seizures induced by electroshock." | 3.67 | [The effect of neuroleptics and neuroleptic/analgesic combinations on the sensitivity to seizures in mice]. ( Frey, HH; Hashem, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ROCHA, E | 1 |
| SILVA, M | 1 |
| LEHMANN, A | 1 |
| FLESS, DA | 1 |
| BLUMEL, G | 1 |
| KUCHER, R | 1 |
| Starke, PR | 1 |
| Weaver, J | 1 |
| Chowdhury, BA | 1 |
| Waterhouse, RG | 1 |
| Saunders, DM | 1 |
| Yamamoto, H | 1 |
| Karadağ, CH | 1 |
| Ulugöl, A | 1 |
| Dökmeci, D | 1 |
| Dökmeci, I | 1 |
| Sawhney, H | 1 |
| Vasishta, K | 1 |
| Rani, K | 1 |
| Vol'f, MSh | 1 |
| Goonewardene, TW | 1 |
| Sentheshanmuganathan, S | 1 |
| Kamalanathan, S | 1 |
| Kanagasunderam, R | 1 |
| Scherkl, R | 1 |
| Hashem, A | 2 |
| Frey, HH | 2 |
| El-Kadre, D | 1 |
| Fanchiotti, GL | 1 |
| Faccin, G | 1 |
| Dashputra, PG | 1 |
| Sharma, ML | 1 |
| Jagtap, MK | 1 |
| Khapre, MD | 1 |
| Rajapurkar, MV | 1 |
| Saxena, VC | 1 |
| Bapat, SK | 1 |
| Dhawan, BN | 1 |
| Frank, GB | 2 |
| Jhamandas, K | 2 |
| Bennett, CR | 1 |
| Monheim, LM | 1 |
| Ruskin, P | 1 |
| Fünfgeld, EW | 1 |
| Rosenberg, FJ | 1 |
| Cooke, WJ | 1 |
| Wessinger, GD | 1 |
22 other studies available for promethazine and Seizures
| Article | Year |
|---|---|
Central effects produced by injection of 48/80 into the cerebral ventricles of mice.
Topics: Animals; Atropine; Central Nervous System; Cerebral Ventricles; Histamine; Injections; Injections, I | 1959 |
[Study of the action of psychotropic drugs on the processes of excitation and inhibition of the C.N.S. by the audiogenic seizure test in rats].
Topics: Animals; Bromides; Epilepsy, Reflex; Hypnotics and Sedatives; Meprobamate; Promethazine; Psychopharm | 1962 |
[Contribution to the therapy of non-hemolytic blood transfusion disorders].
Topics: Blood Transfusion; Chlorpromazine; Cyanosis; Humans; Meperidine; Platelet Transfusion; Promethazine; | 1962 |
Boxed warning added to promethazine labeling for pediatric use.
Topics: Adolescent; Child; Child, Preschool; Contraindications; Drug Labeling; Dystonia; Humans; Infant; Pro | 2005 |
Epileptiform convulsions in children following premedication with Pamergan SP100.
Topics: Body Weight; Child; Female; Humans; Injections, Intramuscular; Male; Meperidine; Promethazine; Scopo | 1967 |
Classical eclampsia with acute intravascular haemolysis.
Topics: Adult; Anemia, Hemolytic; Australia; Blood Chemical Analysis; Blood Platelet Disorders; Chlorpromazi | 1967 |
Protective effect of calmodulin inhibitors against acute cyanide-induced lethality and convulsions in mice.
Topics: Animals; Anticonvulsants; Calmodulin; Chlorpromazine; Cyanides; Dose-Response Relationship, Drug; Ma | 1993 |
The role of histamine H1-receptors in the anticonvulsive effect of morphine against maximal electroconvulsive shock in mice.
Topics: Animals; Dimethindene; Dose-Response Relationship, Drug; Electroshock; Histamine H1 Antagonists; Mal | 1996 |
Comparison of lytic cocktail and magnesium sulphate regimens in eclampsia: a retrospective analysis.
Topics: Adult; Analgesics, Opioid; Anticonvulsants; Blood Pressure; Central Nervous System Agents; Chlorprom | 1998 |
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C | 1975 |
Accidental subarachnoid injection of gallamine. A case report.
Topics: Anesthesia, Spinal; Blood Pressure; Chromatography, Thin Layer; Dexamethasone; Diazepam; Gallamine T | 1975 |
Importance of histamine for seizure susceptibility.
Topics: Animals; Brain; Brocresine; Dimethindene; Histamine; Histamine Antagonists; Histamine H1 Antagonists | 1991 |
[The effect of neuroleptics and neuroleptic/analgesic combinations on the sensitivity to seizures in mice].
Topics: Analgesics; Animals; Antipsychotic Agents; Disease Susceptibility; Droperidol; Drug Interactions; Fe | 1988 |
The "lytic cocktail" induces recurrence of fits in the treatment of eclampsia.
Topics: Chlorpromazine; Delivery, Obstetric; Eclampsia; Female; Humans; Labor, Obstetric; Meperidine; Pregna | 1985 |
[On a case of resuscitation in the Zanoli-Vecchi postoperative convulsive syndrome].
Topics: Adult; Analgesics; Angiotensin II; Ergot Alkaloids; Hemorrhage; Hemostatics; Humans; Intervertebral | 1967 |
Modification of metrazol induced convulsions in rats by antihistaminics.
Topics: Animals; Diphenhydramine; Histamine H1 Antagonists; Pentylenetetrazole; Pheniramine; Piperazines; Pr | 1966 |
An experimental evaluation of the anticonvulsant activity of some antihistaminic drugs.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Female; Histamine H1 Antagoni | 1969 |
Effects of drugs acting alone and in combination on the motor activity of intact mice.
Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central | 1970 |
Effectiveness of various doses of premedicating drugs used for dental procedures in altering toxicity of procaine and lidocaine.
Topics: Dental Care; Drug Synergism; Lidocaine; Meperidine; Preanesthetic Medication; Procaine; Promethazine | 1971 |
[Cerebral convulsions in adults during piperazine treatment].
Topics: Ascariasis; Cerebral Ventriculography; Dementia; Electroencephalography; Female; Humans; Hypnotics a | 1968 |
Effects of general depressant drugs on the electrical responses of isolated slabs of cat's cerebral cortex.
Topics: Action Potentials; Aminobutyrates; Anesthesia, General; Anesthesia, Local; Animals; Cats; Cerebral C | 1970 |
The effect of central nervous system depressants on the tolerance to local anesthetic solutions.
Topics: Anesthetics, Local; Animals; Barbiturates; Chlorpromazine; Drug Synergism; Lidocaine; Male; Meperidi | 1971 |