Page last updated: 2024-08-08 00:24:42
Glycogen synthase kinase-3 beta
A glycogen synthase kinase-3 beta that is encoded in the genome of mouse. [OMA:Q9WV60, PRO:DNx]
Synonyms
GSK-3 beta;
EC 2.7.11.26;
Serine/threonine-protein kinase GSK3B;
2.7.11.1
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea | Mus musculus (house mouse) | IC50 | 0.1000 | 1 | 1 |
| tws 119 | Mus musculus (house mouse) | IC50 | 0.0300 | 1 | 1 |
| azd2858 | Mus musculus (house mouse) | IC50 | 0.0760 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| tws 119 | Mus musculus (house mouse) | EC50 | 1.0000 | 3 | 3 |
| tws 119 | Mus musculus (house mouse) | Kd | 0.1260 | 1 | 1 |