octanoic acid has been researched along with Seizures in 5 studies
octanoic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #1764
octanoic acid : A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess neuronal mechanisms of potential importance in the pathogenesis of hepatic encephalopathy, visual evoked potentials were recorded in rabbits with acute hyperammonemic encephalopathy, postictal coma, and toxin-induced coma resulting from the administration of a combination of subcoma doses of three neurotoxins: ammonia, dimethyldisulfide, and octanoic acid." | 3.67 | Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. ( Ferenci, P; Jones, EA; Pappas, SC; Schafer, DF, 1984) |
| "Finally, using multiple in vivo seizure models, we identify potent lead candidates for the treatment of epilepsy." | 1.42 | Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency. ( Cano-Jaimez, M; Chang, P; Close, AJ; McEvoy, JP; Spencer, J; Walker, MC; Williams, RS; Williams, S; Zuckermann, AM, 2015) |
| "PTZ) seizure tests in mice." | 1.42 | Acute anticonvulsant effects of capric acid in seizure tests in mice. ( Czuczwar, SJ; Gasior, M; Nieoczym, D; Socała, K; Wlaź, P; Żarnowska, I; Żarnowski, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Augustin, K | 1 |
| Khabbush, A | 1 |
| Williams, S | 2 |
| Eaton, S | 1 |
| Orford, M | 1 |
| Cross, JH | 1 |
| Heales, SJR | 1 |
| Walker, MC | 2 |
| Williams, RSB | 1 |
| Chang, P | 1 |
| Zuckermann, AM | 1 |
| Close, AJ | 1 |
| Cano-Jaimez, M | 1 |
| McEvoy, JP | 1 |
| Spencer, J | 1 |
| Williams, RS | 1 |
| Wlaź, P | 2 |
| Socała, K | 2 |
| Nieoczym, D | 2 |
| Żarnowski, T | 1 |
| Żarnowska, I | 1 |
| Czuczwar, SJ | 1 |
| Gasior, M | 1 |
| Pieróg, M | 1 |
| Pappas, SC | 1 |
| Ferenci, P | 1 |
| Schafer, DF | 1 |
| Jones, EA | 1 |
1 review available for octanoic acid and Seizures
| Article | Year |
|---|---|
Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders.
Topics: Alzheimer Disease; Caprylates; Decanoic Acids; Diabetes Mellitus; Diet, Ketogenic; Humans; Neoplasms | 2018 |
4 other studies available for octanoic acid and Seizures
| Article | Year |
|---|---|
Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency.
Topics: Animals; Anticonvulsants; Caprylates; Diet, Ketogenic; Hippocampus; Histone Deacetylase Inhibitors; | 2015 |
Acute anticonvulsant effects of capric acid in seizure tests in mice.
Topics: 3-Hydroxybutyric Acid; Animals; Anticonvulsants; Blood Glucose; Brain; Caprylates; Decanoic Acids; D | 2015 |
Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice.
Topics: 3-Hydroxybutyric Acid; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonis | 2015 |
Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins.
Topics: Ammonia; Animals; Caprylates; Disease Models, Animal; Disulfides; Evoked Potentials, Visual; Galacto | 1984 |