risperidone has been researched along with Seizures in 17 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although the atypical antipsychotic medications appear to be safe in patients with epilepsy, few studies have specifically addressed the use of risperidone in children with seizures." | 9.12 | Use of risperidone in children with epilepsy. ( Baccin, CE; Guerreiro, MM; Holzhausen, SP; Montenegro, MA, 2007) |
| "The aim of this study was to study risperidone use in pediatric patients with comorbid epilepsy and psychiatric disorders." | 7.72 | No seizure exacerbation from risperidone in youth with comorbid epilepsy and psychiatric disorders: a case series. ( Biederman, J; Bourgeois, BF; Fleisher, CA; Gonzalez-Heydrich, J; Hsin, O; Pandina, GJ; Raches, D, 2004) |
| "Although the atypical antipsychotic medications appear to be safe in patients with epilepsy, few studies have specifically addressed the use of risperidone in children with seizures." | 5.12 | Use of risperidone in children with epilepsy. ( Baccin, CE; Guerreiro, MM; Holzhausen, SP; Montenegro, MA, 2007) |
| " Clozapine is the second-generation antipsychotic most frequently associated with seizures, with risperidone appearing to confer a relatively low risk." | 4.82 | Antipsychotic medication and seizures: a review. ( Hedges, D; Jeppson, K; Whitehead, P, 2003) |
| " The first describes the induction of seizures by low-dose venlafaxine in a predisposed individual, and the second describes the development of mild but significant leukopenia with sequential trials of olanzapine and risperidone." | 3.88 | Commentary on 2 Cases of Rare but Serious Side Effects of Commonly Used Medications: Dilemmas in Clinical Decision-making. ( Kahn, DA, 2018) |
| " Under medication with clozapine he had experienced a single event of seizures which were due to hypocalcemia." | 3.74 | [22q11.2 deletion and schizophrenia in childhood and adolescence]. ( Briegel, W, 2007) |
| "The aim of this study was to study risperidone use in pediatric patients with comorbid epilepsy and psychiatric disorders." | 3.72 | No seizure exacerbation from risperidone in youth with comorbid epilepsy and psychiatric disorders: a case series. ( Biederman, J; Bourgeois, BF; Fleisher, CA; Gonzalez-Heydrich, J; Hsin, O; Pandina, GJ; Raches, D, 2004) |
| " However, there are still significant adverse effects and toxicities with this class of medications." | 2.43 | Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer? ( Dubois, D, 2005) |
| " Considerable progress has been made in improving the motor side effect profile with the advent of clozapine and risperidone." | 2.39 | Side effect profiles of new antipsychotic agents. ( Casey, DE, 1996) |
| "Tardive seizure is a serious adverse reaction of electroconvulsive therapy (ECT)." | 1.35 | Tardive seizure and antibiotics: case reports and review of the literature. ( Isse, K; Nakamura, M; Saito, T; Watari, M, 2008) |
| "Psychogenic non-epileptic seizures can co-exist with epileptic seizures." | 1.34 | Development of psychogenic non-epileptic seizures in response to auditory hallucinations. ( Devine, MJ; Duncan, JS, 2007) |
| "Antipsychotic drugs can influence both seizure threshold and seizure activity in different ways." | 1.32 | The impact of neuroleptic medication on seizure threshold and duration in electroconvulsive therapy. ( Barna, I; Gazdag, G; Iványi, Z; Tolna, J, 2004) |
| "When tryptamine was preceded by an apomorphine challenge the effective doses of the 5-HT2 antagonists ritanserin and risperidone for 50% inhibition of the seizures increased by a factor of 2." | 1.28 | Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine. ( Awouters, F; Janssen, PA; Megens, AA; Niemegeers, CJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Unger, M | 1 |
| Xiong, G | 1 |
| Kahn, DA | 1 |
| Rook, JM | 1 |
| Bertron, JL | 1 |
| Cho, HP | 1 |
| Garcia-Barrantes, PM | 1 |
| Moran, SP | 1 |
| Maksymetz, JT | 1 |
| Nance, KD | 1 |
| Dickerson, JW | 1 |
| Remke, DH | 1 |
| Chang, S | 1 |
| Harp, JM | 1 |
| Blobaum, AL | 1 |
| Niswender, CM | 1 |
| Jones, CK | 1 |
| Stauffer, SR | 1 |
| Conn, PJ | 1 |
| Lindsley, CW | 1 |
| Citraro, R | 1 |
| Leo, A | 1 |
| Aiello, R | 1 |
| Pugliese, M | 1 |
| Russo, E | 1 |
| De Sarro, G | 1 |
| Saito, T | 1 |
| Nakamura, M | 1 |
| Watari, M | 1 |
| Isse, K | 1 |
| Hidaka, N | 1 |
| Suemaru, K | 1 |
| Araki, H | 1 |
| Hedges, D | 1 |
| Jeppson, K | 1 |
| Whitehead, P | 1 |
| Gonzalez-Heydrich, J | 1 |
| Pandina, GJ | 1 |
| Fleisher, CA | 1 |
| Hsin, O | 1 |
| Raches, D | 1 |
| Bourgeois, BF | 1 |
| Biederman, J | 1 |
| Gazdag, G | 1 |
| Barna, I | 1 |
| Iványi, Z | 1 |
| Tolna, J | 1 |
| Dubois, D | 1 |
| Holzhausen, SP | 1 |
| Guerreiro, MM | 1 |
| Baccin, CE | 1 |
| Montenegro, MA | 1 |
| Devine, MJ | 1 |
| Duncan, JS | 1 |
| Briegel, W | 1 |
| Casey, DE | 1 |
| Lane, HY | 2 |
| Chang, WH | 2 |
| Chou, JC | 1 |
| Su, KP | 1 |
| Awouters, F | 1 |
| Niemegeers, CJ | 1 |
| Megens, AA | 1 |
| Janssen, PA | 1 |
3 reviews available for risperidone and Seizures
| Article | Year |
|---|---|
Antipsychotic medication and seizures: a review.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothi | 2003 |
Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer?
Topics: Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazepines; Cardiomyopathies; Child | 2005 |
Side effect profiles of new antipsychotic agents.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dyskinesia, Drug-Induced; | 1996 |
1 trial available for risperidone and Seizures
| Article | Year |
|---|---|
Use of risperidone in children with epilepsy.
Topics: Adolescent; Antipsychotic Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Epileps | 2007 |
13 other studies available for risperidone and Seizures
| Article | Year |
|---|---|
Treatment of refractory psychogenic polydipsia with lithium.
Topics: Antipsychotic Agents; Enzyme Inhibitors; Humans; Hyponatremia; Lithium; Male; Polydipsia, Psychogeni | 2017 |
Commentary on 2 Cases of Rare but Serious Side Effects of Commonly Used Medications: Dilemmas in Clinical Decision-making.
Topics: Antipsychotic Agents; Clinical Decision-Making; Humans; Risperidone; Seizures; Venlafaxine Hydrochlo | 2018 |
A Novel M
Topics: Allosteric Regulation; Animals; Antipsychotic Agents; CHO Cells; Cognition; Cognitive Dysfunction; C | 2018 |
Comparative analysis of the treatment of chronic antipsychotic drugs on epileptic susceptibility in genetically epilepsy-prone rats.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Disease Models, Animal; Epi | 2015 |
Tardive seizure and antibiotics: case reports and review of the literature.
Topics: Anti-Bacterial Agents; Antipsychotic Agents; Electroconvulsive Therapy; Electroencephalography; Huma | 2008 |
Serotonin-dopamine antagonism ameliorates impairments of spontaneous alternation and locomotor hyperactivity induced by repeated electroconvulsive seizures in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Dopamine Antagonists; Electroshock; Haloperidol; Hy | 2010 |
No seizure exacerbation from risperidone in youth with comorbid epilepsy and psychiatric disorders: a case series.
Topics: Adolescent; Adult; Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; | 2004 |
The impact of neuroleptic medication on seizure threshold and duration in electroconvulsive therapy.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Brain; Clopenthixol; Clozapine; Dibenzothiazepin | 2004 |
Development of psychogenic non-epileptic seizures in response to auditory hallucinations.
Topics: Adult; Antipsychotic Agents; Epilepsy; Hallucinations; Humans; Male; Risperidone; Seizures | 2007 |
[22q11.2 deletion and schizophrenia in childhood and adolescence].
Topics: Adolescent; Antipsychotic Agents; Calcium; Child; Chromosome Deletion; Chromosomes, Human, Pair 22; | 2007 |
Seizure during risperidone treatment in an elderly woman treated with concomitant medications.
Topics: Age Factors; Aged; Antipsychotic Agents; Astemizole; Comorbidity; Dose-Response Relationship, Drug; | 1998 |
Seizures after discontinuation of low-dose lorazepam from originally seizure-free clozapine regimen: combined effects?
Topics: Adult; Anti-Anxiety Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedul | 1999 |
Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Drug Interac | 1990 |