nikethamide has been researched along with Seizures in 18 studies
Nikethamide: A central nervous system stimulant. It was formerly used in the treatment of barbiturate overdose but is now considered to be of no value for such purposes and may be dangerous. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1229)
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mice pretreated with procaine, lidocaine, and tetracaine had a lower incidence of seizures when convulsive doses of either nikethamide or doxapram hydrochloride were given intraperitoneally." | 3.65 | Interaction between local anesthetics and analeptic drugs. ( Aldrete, JA; Thompson, RG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (94.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, XY | 1 |
| Zhao, JL | 1 |
| Zhang, M | 1 |
| Li, F | 1 |
| Zhao, T | 1 |
| Yang, LQ | 1 |
| PLOTNIKOFF, N | 1 |
| KEITH, J | 1 |
| HEIMANN, M | 1 |
| KEITH, W | 1 |
| PERRY, C | 1 |
| FROMMEL, E | 2 |
| SEYDOUX, J | 2 |
| NAKAJIMA, S | 1 |
| SETNIKAR, I | 1 |
| MAGISTRETTI, MJ | 1 |
| DRIESEN, W | 1 |
| HAHN, F | 2 |
| RUMMEL, W | 1 |
| GARAT, BR | 1 |
| ROSSI RICHERI, OF | 1 |
| TRACCHIA, RO | 1 |
| Sinitskiĭ, VN | 1 |
| Longo, VG | 1 |
| Massotti, M | 1 |
| Sagratella, S | 1 |
| Thompson, RG | 1 |
| Aldrete, JA | 1 |
| Taylor, WJ | 1 |
| Lüdtke, AH | 1 |
| Scharrer, P | 1 |
| Schmidt, L | 1 |
| Frank, GB | 2 |
| Jhamandas, K | 2 |
| Kita, T | 1 |
| Hata, T | 1 |
| Murakami, T | 1 |
| Udall, ND | 1 |
| May, HU | 1 |
18 other studies available for nikethamide and Seizures
| Article | Year |
|---|---|
Sedative, hypnotic and anticonvulsant activities of the ethanol fraction from Rhizoma Pinelliae Praeparatum.
Topics: Animals; Anticonvulsants; Ethanol; Hypnotics and Sedatives; Locomotion; Mice; Mice, Inbred ICR; Nike | 2011 |
STIMULANT EFFECTS OF TETRAHYDROCYCLOHEPTAQUINOLINE DERIVATIVES.
Topics: Acridines; Amphetamine; Amphetamines; Barbiturates; Behavior, Animal; Blood Pressure; Blood Pressure | 1963 |
[ON THE EFFECT OF ETHANOL ON THE BRAIN. RESULTS OF SO-CALLED NEUROPHARMACOLOGIC TESTS IN ANIMALS].
Topics: Alcoholic Intoxication; Amphetamine; Amphetamines; Body Temperature Regulation; Brain; Electroconvul | 1964 |
EFFECTS OF CHEMICAL INJECTION INTO THE RETICULAR FORMATION OF RATS.
Topics: Chlorides; Citrates; Coma; Fear; Injections; Nikethamide; Pentobarbital; Potassium; Procaine; Rats; | 1964 |
CARDIAC EFFECTS OF DIMEFLINE COMPARED WITH THOSE OF OTHER CENTRAL NERVOUS SYSTEM STIMULANTS.
Topics: Aminobutyrates; Bemegride; Benzene; Calcium; Central Nervous System Stimulants; Chlorides; Coronary | 1964 |
STUDY OF THE EFFECTS OF MORPHINE AND NALORPHINE.
Topics: Animals; Body Temperature Regulation; Chlordiazepoxide; Chlorpromazine; Electroshock; Ether; Guinea | 1964 |
[Effect of cardiazol, coramine and pyramidon on the electroencephalogram and electromyelogram in cats and rabbits].
Topics: Aminopyrine; Animals; Cats; Electroencephalography; Lagomorpha; Nikethamide; Pentylenetetrazole; Rab | 1950 |
[Treatment of asthmatic seizures with nebulized 10% coramin suspension].
Topics: Asthma; Humans; Nikethamide; Seizures | 1951 |
[On the mechanism of a disposition to convulsions].
Topics: Animals; Camphor; Injections, Intravenous; Nikethamide; Rabbits; Reflex; Seizures | 1966 |
Convulsant drugs and changes in the electrical activity of the brain: an investigation of the effects of opioids on chemoconvulsions.
Topics: Animals; Brain; Convulsants; Electroencephalography; Electrophysiology; GABA Antagonists; Morphine; | 1983 |
Interaction between local anesthetics and analeptic drugs.
Topics: Anesthetics, Local; Animals; Central Nervous System Stimulants; Doxapram; Drug Interactions; Lidocai | 1975 |
Inhibition of nikethamide by nicotinamide.
Topics: Animals; Mice; Niacinamide; Nikethamide; Seizures; Tachyphylaxis | 1969 |
[The effects of Bemegride, Pentetrazole and Nikethamide on blood pressure, heart rate and respiration in alcohol-intoxicated rats].
Topics: Alcoholic Intoxication; Animals; Bemegride; Blood Pressure; Central Nervous System Stimulants; Heart | 1970 |
Effects of drugs acting alone and in combination on the motor activity of intact mice.
Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central | 1970 |
Effects of general stimulant drugs on the electrical responses of isolated slabs of cat's cerebral cortex.
Topics: Action Potentials; Animals; Bemegride; Caffeine; Cats; Central Nervous System Stimulants; Cerebral C | 1970 |
[Introduction of mass psychology in animals to pharmacology. 6. Mutural relation in simultaneity convulsion and non-convulsin in E1-mice].
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Camphor; Central Nervous Sy | 1970 |
The toxicity of the molluscicides metaldehyde and methiocarb to dogs.
Topics: Acetaldehyde; Animals; Atropine; Carbamates; Dog Diseases; Dogs; Gluconates; Glucose; Hyperemia; Kid | 1973 |
Concerning the depressant activity of analeptics (pentylenetetrazol, bemegride, nikethamide, picrotoxin).
Topics: Anesthesia; Animals; Barbiturates; Bemegride; Depression, Chemical; Guinea Pigs; Nikethamide; Nitrou | 1970 |